Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications & Uses

Tetraderm is indicated for:

Pharmacology

Oxytetracycline slows bacterial growth by blocking protein synthesis. It attaches to the 30S ribosomal subunit, stopping amino-acyl tRNA from reaching the ribosome's A site, and this binding is reversible. Because oxytetracycline is lipophilic, it crosses the cell membrane easily and can also diffuse passively through porin channels in the bacterial membrane. This ointment's broad-spectrum action against both gram-positive and gram-negative organisms is strengthened by polymyxin B, which works particularly well against gram-negative infections, especially those caused by Pseudomonas aeruginosa, where it is considered the antibiotic of choice. Polymyxin B sulfate also shows some antifungal activity.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Oxytetracycline Hydrochloride and Polymyxin B Sulfate Ophthalmic Ointment is applied to the eye 2-4 times a day.

Side Effects

All medicines may cause side effects, but many people have no or minor side effects. No common side effects have been reported with Polytetra when used in small doses. Seek medical attention right away if any of these severe side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); eye swelling or redness.

Cautions & Contraindications

Warnings & Precautions

Serious, life-threatening hypersensitivity (anaphylactic) reactions have been reported in some cats following application of antibiotic ophthalmic preparations. If your cat's face swells, it seems itchy, appears weak, vomits, or has difficulty breathing within 4 hours of application, you should stop treatment and contact your veterinarian immediately. Using oxytetracycline and other antibiotics may lead to an overgrowth of resistant organisms such as Monilia, staphylococci, and other bacterial species. If new infections due to nonsensitive bacteria or fungi appear during therapy, appropriate measures should be taken.

Pregnancy & Breastfeeding

Pregnancy & Breastfeeding: If you become pregnant, let your doctor know right away, so you can talk through the benefits and risks of using this oxytetracycline/polymyxin B sulfate ointment during pregnancy. Whether it passes into breast milk isn't known. If you're breastfeeding or planning to while using this ointment, check with your doctor first and talk over any possible risks to your baby.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Storage

Store at a controlled room temperature of 20° to 25°C.

Common questions about Tetraderm 30 mg

What is Tetraderm 30 mg Ointment?

Tetraderm 30 mg Ointment is a medicine that contains Oxytetracycline + Polymixin B Sulphate. It is made by Rephco Pharmaceuticals Ltd. It belongs to the Anti-infectives & antiseptics group of medicines.

What is Tetraderm used for?

Tetraderm is used for: Conjunctivitis, Inflammation.

What are the side effects of Tetraderm?

All medicines may cause side effects, but many people have no or minor side effects. No common side effects have been reported with Polytetra when used in small doses.

Can I take Tetraderm during pregnancy or while breastfeeding?

Pregnancy & Breastfeeding: If you become pregnant, let your doctor know right away, so you can talk through the benefits and risks of using this oxytetracycline/polymyxin B sulfate ointment during pregnancy. Whether it passes into breast milk isn't known. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

How should I store Tetraderm?

Store at a controlled room temperature of 20° to 25°C.

Do I need a prescription for Tetraderm?

Tetraderm is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 15 Aug 2026