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Other strengths and forms by Incepta Pharmaceuticals Ltd.
Indications & Uses
Tazoskin is indicated for:
Pharmacology
Topical tazarotene works by blocking ornithine decarboxylase (ODC), an enzyme linked to cell proliferation and hyperplasia. It also suppresses MRP8, a marker of inflammation found at high levels in the epidermis of people with psoriasis. In studies on human keratinocyte cultures, the drug inhibits formation of the cornified envelope, whose build-up contributes to psoriatic scale. Tazarotene further induces expression of a gene that may act as a growth suppressor in human keratinocytes, potentially helping to curb epidermal hyperproliferation within treated plaques.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Apply once daily in the evening for psoriasis, generally for up to twelve weeks; for children up to 12 years of age, use and dosage should be decided by the doctor.
For acne, gently cleanse the face first and let the skin dry. Then apply a thin layer of Tazarotene cream once a day, in the evening, over the areas affected by acne, using enough to cover the entire area.
Side Effects
Soritene cream is generally well tolerated. The most common side effects reported with treatment are skin related, including itching, redness, a burning sensation, irritation, peeling, stinging, contact dermatitis, dermatitis, eczema, worsening of psoriasis, skin pain, rash, dry skin, and skin inflammation. Elevated blood triglyceride levels and swelling of the extremities have also been reported.
Cautions & Contraindications
Warnings & Precautions
Soritene cream should be applied only to the affected areas and used for external skin application only. Contact with the eyes, eyelids, and mouth should be avoided; if the cream comes into contact with the eyes, rinse thoroughly with water. Retinoids should not be used on eczematous skin, as they may cause severe irritation. Because the skin becomes more prone to burning, exposure to sunlight (including sunlamps) should be avoided unless considered medically necessary, in which case exposure should be kept to a minimum while using Soritene cream. Soritene cream should be used with caution in patients also taking drugs known to cause photosensitivity (such as thiazides, tetracyclines, fluoroquinolones, phenothiazines, or sulfonamides), since this raises the risk of increased sensitivity to light.
Contraindications
Tazarotene cream should not be used by women who are pregnant or who may become pregnant, since retinoids as a class can harm the developing fetus. If a woman becomes pregnant while using this medicine, or if it is used during pregnancy, it should be stopped right away and she should be informed of the possible risk to her unborn child. Women who could become pregnant should be made aware of this risk and advised to use effective contraception while using Tazarotene cream.
Pregnancy & Breastfeeding
There are no adequate and well-controlled studies of Tazarotene in pregnant women. When used only on the face for acne, systemic absorption may be lower because less surface area is treated, but Tazarotene is still a teratogenic substance, and the level of exposure needed to cause harm in humans is not known. It is also not known whether this drug passes into human breast milk, so caution should be exercised when Tazarotene is given to a nursing woman.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Using too much Tazarotene cream 0.1% on the skin can cause marked redness, peeling or discomfort. The cream is not for oral use. If someone swallows it, the effects may be the same as those seen with too much vitamin A (hypervitaminosis A) or other retinoids. In that case the patient should be monitored, and supportive measures given as necessary.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Tazarotene below 30°C, away from light and moisture. Keep it out of the reach of children.
Common questions about Tazoskin 0.1%
What is Tazoskin 0.1% Cream?
Tazoskin 0.1% Cream is a medicine that contains Tazarotene. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Topical retinoid and related preparations group of medicines.
What is Tazoskin used for?
Tazoskin is used for: Acne Vulgaris, Psoriasis.
What are the side effects of Tazoskin?
Soritene cream is generally well tolerated. The most common side effects reported with treatment are skin related, including itching, redness, a burning sensation, irritation, peeling, stinging, contact dermatitis, dermatitis, eczema, worsening of psoriasis, skin pain, rash, dry skin, and skin inflammation.
Can I take Tazoskin during pregnancy or while breastfeeding?
There are no adequate and well-controlled studies of Tazarotene in pregnant women. When used only on the face for acne, systemic absorption may be lower because less surface area is treated, but Tazarotene is still a teratogenic substance, and the level of exposure needed to cause harm in humans is not known. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Tazoskin?
Using too much Tazarotene cream 0.1% on the skin can cause marked redness, peeling or discomfort. The cream is not for oral use. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Tazoskin?
Store Tazarotene below 30°C, away from light and moisture. Keep it out of the reach of children.
Do I need a prescription for Tazoskin?
Tazoskin is a prescription (Rx) medicine. Take it as your doctor advises.