More from Supraphen
Other strengths and forms by G. A. Company Ltd.
Indications & Uses
Treats acute bacterial ear infections.
Pharmacology
Chloramphenicol inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome, blocking peptide bond formation by peptidyl transferase. It acts both bacteriostatically and bactericidally against H. influenzae, N. meningitidis, and S. pneumoniae.
Lidocaine is an amide-type local anaesthetic. It stabilises the neuronal membrane and blocks sodium ion movement, which is needed for impulse conduction. In the heart, lidocaine reduces ventricular depolarisation during diastole and lowers automaticity in the His-Purkinje system. It also shortens the duration of the action potential and the effective refractory period.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Otic (aural) use for otitis externa: Instill 2 to 3 drops into the ear two to three times daily.
Side Effects
Side-effect information is not available for this brand yet.
Cautions & Contraindications
Warnings & Precautions
Avoid using this medicine for extended periods. If any signs of a local allergic reaction appear, stop use right away.
Contraindications
Contraindicated in patients with a history of hypersensitivity or toxic reaction to the drug, or with a perforated eardrum. Also avoid use in herpes simplex and other viral infections of the eye or ear, and in fungal (mycotic) conditions.
Pregnancy & Breastfeeding
Pregnancy Category C & B. In animal studies, the drug has been shown to harm the fetus, and there are no adequate, well-controlled studies in pregnant women, but its potential benefits may justify use in pregnant women despite the possible risks. Alternatively, animal studies have not shown a risk to the fetus, though human data remain limited, or animal studies did show harm while adequate, well-controlled studies in pregnant women found no risk to the fetus in any trimester.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Drug Interactions
Common questions about Supraphen 500 mg
What is Supraphen 500 mg Ear Drop?
Supraphen 500 mg Ear Drop is a medicine that contains Chloramphenicol + Lidocaine Hydrochloride. It is made by G. A. Company Ltd. It belongs to the Anti-infectives & antiseptics group of medicines.
What is Supraphen used for?
Treats acute bacterial ear infections.
Can I take Supraphen during pregnancy or while breastfeeding?
Pregnancy Category C & B. In animal studies, the drug has been shown to harm the fetus, and there are no adequate, well-controlled studies in pregnant women, but its potential benefits may justify use in pregnant women despite the possible risks. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Can I take other medicines with Supraphen?
Some medicines can interact with Chloramphenicol + Lidocaine Hydrochloride, for example: Phenytoin, Chloramphenicol, Phenobarbitone, Iron, Rifampicin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Supraphen?
Supraphen is a prescription (Rx) medicine. Take it as your doctor advises.