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Other brands with the same active ingredient
These brands contain the same active ingredient (Sulindac). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Sudac 100 is indicated for:
Pharmacology
Sulindac is a non-steroidal anti-inflammatory drug that relieves pain, reduces inflammation, and brings down fever, likely by blocking prostaglandin synthetase, the mechanism thought to underlie NSAIDs generally. Once absorbed, sulindac is first oxidised to a sulphone and then reversibly reduced to a sulphide, and it is this sulphide form that is biologically active, working by inhibiting prostaglandin synthesis.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Sulindac is taken by mouth twice a day with food. The maximum dose is 400 mg per day; doses above 400 mg per day are not recommended. For osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, the recommended starting dose is 150 mg. For acute painful shoulder and acute gouty arthritis, the recommended dose is 200 mg twice a day. The dose may be lowered or raised depending on the response. Once a satisfactory response has been achieved, the dose may be reduced according to the response. Or, as directed by a registered physician.
Side Effects
Stomach and bowel problems are the most common side effects of sulindac. These include abdominal pain, nausea and constipation. Ulcers and bleeding in the stomach or gut can also occur. The side effects most often reported on the nervous system are drowsiness, dizziness, headache and nervousness. Other side effects that may occur include depression, ringing in the ears (tinnitus), confusion, light-headedness, difficulty sleeping, psychiatric disturbances, fainting, convulsions, coma, nerve damage in the hands or feet (peripheral neuropathy), blurred vision and other eye problems, fluid retention and weight gain, high blood pressure, blood in the urine, skin rashes, itching, hives, mouth sores, hair loss and allergic (hypersensitivity) reactions. A hypersensitivity syndrome has also been reported. It may involve fever and chills, skin rashes or other skin changes, liver damage, kidney damage (including kidney failure), low white blood cell count (leukopenia), low platelet count (thrombocytopenia), raised eosinophil count, swollen glands or lymph nodes, and joint pain. Further reported effects include low white blood cell count, purpura (purple spots from bleeding under the skin), low platelet count, aplastic anaemia, haemolytic anaemia, agranulocytosis (a severe drop in certain white blood cells), nosebleeds, high blood sugar, high blood potassium and vaginal bleeding. There have also been reports of hepatitis, jaundice and kidney failure.
Cautions & Contraindications
Warnings & Precautions
Sulinzen should be used with caution in patients with impaired kidney function, bleeding disorders, epilepsy, parkinsonism or psychiatric disorders. In patients with liver impairment, the half-life of Sulinzen is prolonged and a reduction in the daily dose may be needed. Anaemia is sometimes seen in patients receiving NSAIDs together with Sulinzen.
Contraindications
Sulindac should not be used by people who are allergic to it, or by those who have had an acute asthma attack, hives (urticaria) or a runny nose (rhinitis) triggered by aspirin or other non-steroidal anti-inflammatory drugs. It is also not suitable for people with a history of active gastrointestinal bleeding or peptic ulcers. Sulindac should not be given to children, or to women who are pregnant or breastfeeding.
Pregnancy & Breastfeeding
Pregnancy: During the first two trimesters, Sulindac should be used only if the potential benefit justifies the potential risk to the foetus. It is not recommended during the third trimester.
Breastfeeding: It is not known whether Sulindac passes into human milk. The decision to stop breastfeeding or stop the medicine should be made after weighing how important the medicine is to the mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Patients with renal impairment: Sulin should be given with caution to people whose kidney function is impaired. The same care applies to those with bleeding disorders, epilepsy, parkinsonism or psychiatric disorders.
Patients with hepatic impairment: When liver function is impaired, the half life of Sulin is prolonged, so a lower daily dose may be needed.
Overdose
Symptoms reported after an overdose of Sulin have mostly pointed to toxicity in the gastro-intestinal tract, the kidneys and the central nervous system. Treatment is symptomatic and supportive.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Sulindac below 25°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Sudac 100 100 mg
What is Sudac 100 100 mg Tablet?
Sudac 100 100 mg Tablet is a medicine that contains Sulindac. It is made by Drug International Unani Ltd. It belongs to the Drugs for Osteoarthritis group of medicines.
What is Sudac 100 used for?
Sudac 100 is used for: Neuropathic Pain, Osteoarthritis, Rheumatoid Arthritis.
What are the side effects of Sudac 100?
Stomach and bowel problems are the most common side effects of sulindac. These include abdominal pain, nausea and constipation.
Can I take Sudac 100 during pregnancy or while breastfeeding?
Pregnancy: During the first two trimesters, Sulindac should be used only if the potential benefit justifies the potential risk to the foetus. It is not recommended during the third trimester. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Sudac 100?
Symptoms reported after an overdose of Sulin have mostly pointed to toxicity in the gastro-intestinal tract, the kidneys and the central nervous system. Treatment is symptomatic and supportive. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Sudac 100?
Store Sulindac below 25°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Sudac 100?
Some medicines can interact with Sulindac, for example: Aspirin, Paracetamol. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Sudac 100?
Sudac 100 is a prescription (Rx) medicine. Take it as your doctor advises.