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Other strengths and forms by Incepta Pharmaceuticals Ltd.
Indications & Uses
Spusoft is indicated for:
Pharmacology
Erdosteine is a prodrug, which means the body has to change it before it works. It is metabolised into N-thiodiglycolyl-homocysteine, and this process forms free thiol groups. These groups open the disulphide bonds of the bronchial mucoproteins, so the mucus and purulent sputum become less viscous.
Erdosteine also works against the local formation of free radicals. It inhibits the activity of the elastase enzyme as well, and it reduces the adhesion of bacteria to epithelial cells.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and elderly patients above 18 years usually take 1 Erdosteine capsule twice daily for 10 days. In chronic cases, studies show Erdosteine can be given for up to 12 months, or for as long as the physician directs. The capsule can be taken with or without food.
Side Effects
Erdosteine most often causes epigastric pain. Other side effects people may notice are headache, cold, changes in taste, nausea, vomiting and diarrhea. Angioedema and other allergic skin reactions can also happen.
Cautions & Contraindications
Warnings & Precautions
Erdosteine should be used with caution in people who have mild liver failure. In that case, the dose should not go above 300 mg per day.
Contraindications
Erdosteine must not be given to anyone who is hypersensitive to Erdosteine. It should also not be used in patients whose creatinine clearance is below 25 ml/min, or in those with severe liver failure.
Pregnancy & Breastfeeding
Erdosteine is not recommended for women who are pregnant or breast-feeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Renal impairment: Erdosteine is contraindicated when CrCl is below 25 ml/min.
Hepatic impairment: In mild to moderate cases, the maximum is 300 mg daily. In severe cases it is contraindicated.
Storage
Store Erdosteine in a dry place, away from light and heat. Keep it out of the reach of children.
Common questions about Spusoft 175 mg/5 ml
What is Spusoft 175 mg/5 ml Syrup?
Spusoft 175 mg/5 ml Syrup is a medicine that contains Erdosteine. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Cough expectorants & mucolytics group of medicines.
What is Spusoft used for?
Spusoft is used for: Chronic Obstructive Pulmonary Disease, Bronchitis.
What are the side effects of Spusoft?
Erdosteine most often causes epigastric pain. Other side effects people may notice are headache, cold, changes in taste, nausea, vomiting and diarrhea.
Can I take Spusoft during pregnancy or while breastfeeding?
Erdosteine is not recommended for women who are pregnant or breast-feeding. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Spusoft?
Store Erdosteine in a dry place, away from light and heat. Keep it out of the reach of children.
Do I need a prescription for Spusoft?
Spusoft is a prescription (Rx) medicine. Take it as your doctor advises.