Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Other brands with the same active ingredient

These brands contain the same active ingredient (Doxepin). Same strength and form. Confirm the switch with your doctor or pharmacist.

Indications & Uses

Somopin 3 is indicated for:

Pharmacology

Doxepin hydrochloride belongs to a class of medicines called dibenzoxepin tricyclic antidepressants. Although doxepin HCl does block H1 and H2 histamine receptors, exactly how this helps relieve itching (its antipruritic effect) is not fully understood. It can make many patients drowsy, and this sedation may lessen awareness generally, including awareness of itching.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Adults and children over 12 years: apply a thin layer 3 to 4 times daily. The usual maximum is 3 g per application and 12 g in total per day. The area covered should be less than 10% of the body surface area.

Use in children: Doxiderm cream is not recommended for pediatric patients, as safe conditions for its use in children have not been established.

Use in elderly patients: Dose selection for elderly patients should be cautious, usually starting at the low end of the dosing range. This reflects the greater frequency of reduced liver, kidney or heart function, as well as other illnesses or concurrent drug therapy, in this age group.

Side Effects

Doxepin may cause drowsiness. When applied to the skin, it can cause local burning, stinging, irritation, tingling or a rash. Systemic side effects have also been reported, including antimuscarinic effects, headache, fever, dizziness and gastrointestinal disturbances.

Cautions & Contraindications

Warnings & Precautions

Care is needed in people who are prone to angle-closure glaucoma, urinary retention, severe liver impairment, or mania, and also during pregnancy and breast-feeding. Because doxepin can cause drowsiness, it may impair the ability to perform skilled tasks such as driving, so patients should take care.

Contraindications

Doxepin should not be used in people with untreated narrow-angle glaucoma or a tendency to urinary retention, because it has an anticholinergic effect. It is also not suitable for anyone who has previously shown sensitivity to any of its components.

Pregnancy & Breastfeeding

Pregnancy category B. No adequate, well-controlled studies have been done in pregnant women, so doxepin should be used during pregnancy only if the need is clear. Doxepin passes into human breast milk after it is taken by mouth, and it may also pass into breast milk when doxepin cream is applied to the skin.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Overdose

If too much Doxepin cream is applied to the skin, the person may develop cardiac dysrhythmias, severe hypotension, convulsions and CNS depression, which can go as far as coma. Changes in the electrocardiogram, particularly in the QRS axis or width, are clinically significant signs of tricyclic antidepressant toxicity.

Other signs of overdose may include confusion, disturbed concentration, transient visual hallucinations, dilated pupils, agitation, hyperactive reflexes, stupor, drowsiness, muscle rigidity, vomiting, hypothermia and hyperpyrexia.

⚠️ In an emergency call 999 or go to the nearest hospital emergency department.

Storage

Store Doxepin below 30°C, away from light and moisture. Keep it out of the reach of children.

Drug Interactions

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Moderate Cimetidine
Moderate Ramelteon

Common questions about Somopin 3 3 mg

What is Somopin 3 3 mg Tablet?

Somopin 3 3 mg Tablet is a medicine that contains Doxepin. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Tricyclic & related anti-depressant drugs group of medicines.

What is Somopin 3 used for?

Somopin 3 is used for: Eczema, Urticaria.

What are the side effects of Somopin 3?

Doxepin may cause drowsiness. When applied to the skin, it can cause local burning, stinging, irritation, tingling or a rash.

Can I take Somopin 3 during pregnancy or while breastfeeding?

Pregnancy category B. No adequate, well-controlled studies have been done in pregnant women, so doxepin should be used during pregnancy only if the need is clear. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

What happens if I take too much Somopin 3?

If too much Doxepin cream is applied to the skin, the person may develop cardiac dysrhythmias, severe hypotension, convulsions and CNS depression, which can go as far as coma. Changes in the electrocardiogram, particularly in the QRS axis or width, are clinically significant signs of tricyclic antidepressant toxicity. In an emergency call 999 or go to the nearest hospital emergency department.

How should I store Somopin 3?

Store Doxepin below 30°C, away from light and moisture. Keep it out of the reach of children.

Can I take other medicines with Somopin 3?

Some medicines can interact with Doxepin, for example: Cimetidine, Ramelteon. Tell your doctor or pharmacist about every medicine you take.

Do I need a prescription for Somopin 3?

Somopin 3 is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 15 Aug 2026