Indications & Uses
Rosen Plus is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Take one tablet of Drospirenone + Ethinyl Estradiol + Levomefolate by mouth at the same time every day. The failure rate may go up when pills are missed or taken the wrong way. To get the full contraceptive and PMDD effect, take the pills as directed, in the order shown on the blister pack. A single missed pill should be taken as soon as it is remembered.
There are two ways to start. The patient can begin on the first day of her menstrual period (Day 1 Start) or on the first Sunday after her period begins (Sunday Start).
Day 1 Start: In the first cycle, tell the patient to take one pink pill daily, beginning on Day 1 of her menstrual cycle (the first day of menstruation is Day 1). She takes one pink pill daily for 24 consecutive days, then one light orange tablet daily on Days 25 through 28. The pills should be taken in the order shown on the pack, at the same time each day, preferably after the evening meal or at bedtime with some liquid, as needed. They can be taken without regard to meals. If the first pill is taken later than the first day of the menstrual cycle, it should not be counted as effective contraception until after the first 7 consecutive days of use. Tell the patient to use a non-hormonal contraceptive as backup during those first 7 days. The possibility of ovulation and conception before starting the medicine should be considered.
Sunday Start: In the first cycle, tell the patient to take one pink pill daily, beginning on the first Sunday after her period starts. She takes one pink pill daily for 24 consecutive days, then one light orange tablet daily on Days 25 through 28. The pills should be taken in the order shown on the pack, at the same time each day, preferably after the evening meal or at bedtime with some liquid, as needed. They can be taken without regard to meals. The pill should not be counted as effective contraception until after the first 7 consecutive days of use. Tell the patient to use a non-hormonal contraceptive as backup during those first 7 days. The possibility of ovulation and conception before starting the medicine should be considered.
The patient should start her next 28-day pack, and every pack after that, on the same day of the week she started the first one, following the same schedule. She begins the pink tablets on the day after the last light orange folate tablet, whether or not a menstrual period has occurred or is still going on. If any later cycle is started more than one day after the last light orange tablet, she should use another method of contraception until she has taken a pink pill daily for seven consecutive days.
When switching from a different birth control pill, start this pill on the same day a new pack of the previous oral contraceptive would have been started.
Side Effects
With Drospirenone + Ethinyl Estradiol + Levomefolate, the reactions seen most often (in 2% or more of users) in the contraception, acne and folate clinical trials were headache or migraine (5.9%), menstrual irregularities (4.1%), nausea or vomiting (3.5%) and breast pain or tenderness (3.2%). In the PMDD clinical trials, the most frequent reactions, also at 2% or more, were menstrual irregularities (24.9%), nausea (15.8%), headache (13.0%), breast tenderness (10.5%), fatigue (4.2%), irritability (2.8%), decreased libido (2.8%), increased weight (2.5%) and affect lability (2.1%).
Cautions & Contraindications
Warnings & Precautions
Vascular risks: Stop this contraceptive pill if a thrombotic event occurs. Stop it at least 4 weeks before major surgery and keep it stopped through 2 weeks after. In women who are not breastfeeding, start no earlier than 4 weeks after delivery. COCs containing DRSP may carry a higher risk of venous thromboembolism (VTE) than COCs containing levonorgestrel or some other progestins. Before starting this pill in a new COC user, or in a woman switching from a contraceptive that does not contain DRSP, weigh the risks and benefits of a DRSP-containing COC against her own risk of a VTE. Hyperkalemia: DRSP has antimineralocorticoid activity, so don't use this pill in patients predisposed to hyperkalemia. In women on long-term treatment with medicines that may raise serum potassium concentration, check serum potassium during the first treatment cycle. Liver disease: Discontinue this contraceptive pill if jaundice occurs. High blood pressure: Do not prescribe this pill for women with uncontrolled hypertension, or hypertension with vascular disease. Carbohydrate and lipid metabolic effects: Monitor prediabetic and diabetic women who take this pill. For women with uncontrolled dyslipidemia, consider an alternate contraceptive method. Headache: If there is a significant change in headaches, evaluate it and discontinue this pill if indicated. Uterine bleeding: Evaluate irregular bleeding or amenorrhea.
Contraindications
Drospirenone + Ethinyl Estradiol + Levomefolate should not be used in people with renal impairment, adrenal insufficiency, a high risk of arterial or venous thrombotic diseases, undiagnosed abnormal uterine bleeding, breast cancer or other estrogen- or progestin-sensitive cancer, liver tumors or liver disease, or pregnancy.
Pregnancy & Breastfeeding
Nursing mothers shouldn't use this medicine, as it can reduce milk production.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store this medicine below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Common questions about Rosen Plus 0.03 mg+3 mg+0.415 mg
What is Rosen Plus 0.03 mg+3 mg+0.415 mg Tablet?
Rosen Plus 0.03 mg+3 mg+0.415 mg Tablet is a medicine that contains Drospirenone + Ethinyl Estradiol + Levomefolate. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Oral Contraceptive preparations group of medicines.
What is Rosen Plus used for?
Rosen Plus is used for: Headache, Pain, Acne Vulgaris, Anxiety, Contraception.
What are the side effects of Rosen Plus?
With Drospirenone + Ethinyl Estradiol + Levomefolate, the reactions seen most often (in 2% or more of users) in the contraception, acne and folate clinical trials were headache or migraine (5.9%), menstrual irregularities (4.1%), nausea or vomiting (3.5%) and breast pain or tenderness (3.2%). In the PMDD clinical trials, the most frequent reactions, also at 2% or more, were menstrual irregularities (24.9%), nausea (15.8%), headache (13.0%), breast tenderness (10.5%), fatigue (4.2%), irritability (2.8%), decreased libido (2.8%), increased weight (2.5%) and affect lability (2.1%).
Can I take Rosen Plus during pregnancy or while breastfeeding?
Nursing mothers shouldn't use this medicine, as it can reduce milk production. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Rosen Plus?
Store this medicine below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Do I need a prescription for Rosen Plus?
Rosen Plus is a prescription (Rx) medicine. Take it as your doctor advises.