Pricing
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All price changes →Indications & Uses
Revatol is indicated for:
Pharmacology
Mahadrakkharist, the grape extract, contains bioflavonoid-like ingredients called "proanthocyanidins" (PCOs or OPCs). Proanthocyanidins are believed to protect cell membranes by neutralizing a particularly harmful kind of free radical called "lipid peroxides". PCOs may strengthen the capillary walls and the skin. They have also been reported to inhibit the release of inflammatory chemicals such as histamine and prostaglandins. Because they are reported to slow histamine release from mast cells, PCOs have been used in allergies and asthma.
Resveratrol is a molecule with antioxidant and anti-inflammatory properties, and it may protect against COPD and asthma (Wood 2010). A cell culture study found that resveratrol inhibited the release of all measured inflammatory mediators (cytokines) from immune cells taken from the alveoli of smokers and non-smokers with COPD. In airway smooth muscle cells, resveratrol reduces the release of inflammatory mediators but keeps the signaling of a protein called vascular endothelial growth factor (VEGF), which may protect against emphysema. More recently, the anti-inflammatory effects of resveratrol have been linked to inhibition of the transcription factor NF-kB, possibly through inhibition of l-kB kinase.
Resveratrol has several activities that may account for its possible cardioprotective action. These include inhibition of the oxidation of low-density lipoprotein (LDL), inhibition of smooth muscle cell proliferation and inhibition of platelet aggregation. It has also been found to strongly inhibit the production of superoxide anion and hydrogen peroxide by macrophages stimulated with lipopolysaccharides or phorbol esters. It increases nitric oxide, decreases lactate dehydrogenase levels in the carotid blood, and is effective against ischemia-reperfusion induced arrythmias.
The triterpenes roxburghiadiol A and B, isolated from the plant Aglaia roxburghiana, have potent anti-inflammatory activity, and mast cell degranulation was induced by A. roxburghiana extracts and by the triterpenes.
Pharmacokinetics
Animal studies and a limited number of human studies suggest that resveratrol is absorbed from the gastrointestinal tract after it is swallowed. After it crosses the small intestine and enters the blood circulation, it is found as a glucuronide conjugate. In humans, five metabolites of resveratrol have been detected in urine: resveratrol monosulphate, two isomeric forms of resveratrol monoglucuronide, dihydroresveratrol monosulphate and dihydroresveratrol monoglucuronide. Of these sulphate and glucuronide conjugates, 56% are excreted through urine (Baur and Sinclair, 2006).
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Mahadrakkharist is partly effective because of the grape content in it. The recommended daily dose of resveratrol is 8 mg/kg body weight, and each 5 ml of the syrup contains 36 mg resveratrol as a fluid extract. So the daily dose works out like this.
Children under 12 years take 1 to 2 teaspoonfuls (5 to 10 ml) 2 times daily after meal. For those above 12 years and for adults, the dose is 3 to 4 teaspoonfuls (15 to 20 ml) 2 times daily after meal, for 4 to 8 weeks or as directed by the physician.
Side Effects
Mahadrakkharist (Drakkha) has no side effects at the therapeutic doses mentioned above. It has been used safely as an ayurvedic medicine for hundreds of years. In very rare cases, though, people have reported stomach pain, headache and an allergic reaction.
Cautions & Contraindications
Warnings & Precautions
Drakkha is generally well tolerated, but take care if you have hypertension, liver disease, alcohol dependence or diabetes. If you have any other medical condition, talk to your doctor before you take Mahadrakkharist [Grape extract]. Lactobacillus products (for example probiotics) should be taken at least 2 hours apart from it.
Pregnancy & Breastfeeding
Women who are pregnant or breastfeeding should talk to a doctor before using Mahadrakkharist. That said, the medical literature has no report of harmful effects on the development of the baby during pregnancy, or on infants who are breast-fed.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Mahadrakkharist in a cool, dry place, away from direct sunlight. Keep the medicine out of the reach of children.
Drug Interactions
Common questions about Revatol 200 ml
What is Revatol 200 ml Syrup?
Revatol 200 ml Syrup is a medicine that contains Mahadrakkharist [Grape extract]. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Herbal and Nutraceuticals group of medicines.
What is Revatol used for?
Revatol is used for: Asthma, Chronic Obstructive Pulmonary Disease, Tuberculosis.
What are the side effects of Revatol?
Mahadrakkharist (Drakkha) has no side effects at the therapeutic doses mentioned above. It has been used safely as an ayurvedic medicine for hundreds of years.
Can I take Revatol during pregnancy or while breastfeeding?
Women who are pregnant or breastfeeding should talk to a doctor before using Mahadrakkharist. That said, the medical literature has no report of harmful effects on the development of the baby during pregnancy, or on infants who are breast-fed. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Revatol?
Store Mahadrakkharist in a cool, dry place, away from direct sunlight. Keep the medicine out of the reach of children.
Can I take other medicines with Revatol?
Some medicines can interact with Mahadrakkharist [Grape extract], for example: Aspirin, Warfarin Sodium. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Revatol?
Revatol is a prescription (Rx) medicine. Take it as your doctor advises.