Renafor-G
Rx9 mcg+4.8 mcg • Metered-Dose Inhaler (MDI)
Indications & Uses
Renafor-G is indicated for:
Pharmacology
This preparation contains two bronchodilators. One is glycopyrronium, a long-acting muscarinic antagonist (LAMA), and the other is formoterol, a long-acting β2-adrenergic agonist (LABA) that starts working rapidly. Glycopyrronium binds with similar affinity to the muscarinic receptor subtypes M1 to M5. In the airways, its effect comes from blocking the M3 receptor at the smooth muscle, which leads to bronchodilation. Formoterol relaxes airway smooth muscle directly. It does this by activating adenylyl cyclase, which raises the level of cyclic AMP.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults should take 2 puffs twice a day, one in the morning and one in the evening (so that's 2 puffs each time). In patients with severe renal impairment, Glycopyrronium Bromide + Formoterol Fumarate should be used only if the expected benefit outweighs the risk.
Side Effects
Cough and urinary tract infection are the side effects people report most often with glycopyrronium bromide and formoterol fumarate. Other side effects can also happen. These include sudden breathing problems, headache, tremor, nervousness and rash. Some people get swelling of the face, mouth and tongue, or hives. Others may have increased blood pressure, chest pain, irregular heartbeat, muscle spasm or muscle weakness. Eye pain or discomfort and urinary retention are also possible.
Cautions & Contraindications
Warnings & Precautions
Glycopyrronium Bromide + Formoterol Fumarate should not be used together with another medicine that contains a LABA, because of the risk of overdose. It is not indicated for the relief of acute bronchospasm. Don't start it in acutely deteriorating COPD, and don't use it to treat acute symptoms. If paradoxical bronchospasm occurs, stop Glycopyrronium Bromide + Formoterol Fumarate and start alternative therapy. Use it with caution in patients with cardiovascular disorders. Use it with patients who have convulsive disorders, thyrotoxicosis, diabetes mellitus and ketoacidosis, and be alert to hypokalemia and hyperglycemia. Worsening of narrow angle glaucoma may occur, so use it with caution in patients with narrow-angle glaucoma. Worsening of urinary retention may also occur, so take care in patients with prostatic hyperplasia or bladder-neck obstruction.
Contraindications
Glycopyrronium Bromide + Formoterol Fumarate must not be given to people with asthma unless they are also using a long-term asthma control medicine. This applies to all LABAs. It is also contraindicated in anyone who is hypersensitive to glycopyrronium bromide, formoterol fumarate or any other component of the product.
Pregnancy & Breastfeeding
No data are available on the use of glycopyrronium bromide with formoterol fumarate in pregnant women.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Glycopyrronium Bromide + Formoterol Fumarate at no higher than 30°C, and don't expose it to temperatures above 50°C. The container is pressurized, so don't pierce it. Keep it out of the reach of children.
Drug Interactions
Common questions about Renafor-G 9 mcg+4.8 mcg
What is Renafor-G 9 mcg+4.8 mcg Metered-Dose Inhaler (MDI)?
Renafor-G 9 mcg+4.8 mcg Metered-Dose Inhaler (MDI) is a medicine that contains Glycopyrronium Bromide + Formoterol Fumarate. It is made by Renata PLC.
What is Renafor-G used for?
Renafor-G is used for: Chronic Obstructive Pulmonary Disease, Bronchitis.
What are the side effects of Renafor-G?
Cough and urinary tract infection are the side effects people report most often with glycopyrronium bromide and formoterol fumarate. Other side effects can also happen.
Can I take Renafor-G during pregnancy or while breastfeeding?
No data are available on the use of glycopyrronium bromide with formoterol fumarate in pregnant women. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Renafor-G?
Store Glycopyrronium Bromide + Formoterol Fumarate at no higher than 30°C, and don't expose it to temperatures above 50°C. The container is pressurized, so don't pierce it.
Can I take other medicines with Renafor-G?
Some medicines can interact with Glycopyrronium Bromide + Formoterol Fumarate, for example: Formoterol Fumarate. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Renafor-G?
Renafor-G is a prescription (Rx) medicine. Take it as your doctor advises.