More from Reglin
Other strengths and forms by General Pharmaceuticals Ltd.
Indications & Uses
Reglin is indicated for:
Pharmacology
Repaglinide attaches to specific receptors on the cell membrane, prompting ATP-dependent K+ channels to close and the membrane to depolarise. This allows Ca++ to flow into the cell, raising intracellular Ca++ levels and triggering the release of insulin.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For patients who have not been treated before, or whose HbA1c is below 8%, the starting dose should be 0.5 mg before each meal. For patients previously treated with blood glucose-lowering drugs and whose HbA1c is above 8%, the initial dose is 1 or 2 mg before each meal. Repaglinide should be taken immediately before each meal, or up to 30 minutes beforehand. The dose should be adjusted according to response at intervals of 1 to 2 weeks. Up to 4 mg may be given as a single dose, with a maximum of 16 mg daily.
Side Effects
The most common side effects of Repanid are hypoglycaemia (low blood sugar) and its related symptoms. Other side effects include upper respiratory tract infections, diarrhoea, constipation, nausea and vomiting. Hypersensitivity (allergic) reactions may occur, including rashes and urticaria (hives).
Cautions & Contraindications
Warnings & Precautions
Insulin should be used in place of repaglinide during intercurrent illness (such as myocardial infarction, coma, infection or trauma) and around the time of surgery. All oral glucose-lowering medicines can cause hypoglycaemia. To reduce this risk, repaglinide should be taken with meals.
Contraindications
Repaglinide should not be used in patients with diabetic ketoacidosis, with or without coma, in patients with type 1 diabetes mellitus, or in anyone with a known hypersensitivity to the drug or its inactive ingredients.
Pregnancy & Breastfeeding
Safety in pregnant women has not been established. Repaglinide should be used during pregnancy only if it is clearly needed. It is not known whether Repaglinide is excreted in human milk. Because many drugs are excreted in human milk, and because nursing infants could face serious adverse reactions from Repaglinide, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
In studies, patients who took up to 80 mg of Repaglinide had few adverse effects apart from a fall in blood glucose. When meals were given along with these high doses, hypoglycemia did not occur. Severe hypoglycemic reactions, with coma, seizure or other neurological impairment, are uncommon.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Repaglinide at a temperature no higher than 30°C. Keep it away from light, and make sure children can't reach it.
Drug Interactions
Common questions about Reglin 5 mg
What is Reglin 5 mg Tablet?
Reglin 5 mg Tablet is a medicine that contains Repaglinide. It is made by General Pharmaceuticals Ltd. It belongs to the Meglitinide Analogues group of medicines.
What is Reglin used for?
Reglin is used for: Type 2 Diabetes Mellitus, Diabetes Mellitus.
What are the side effects of Reglin?
The most common side effects of Repanid are hypoglycaemia (low blood sugar) and its related symptoms. Other side effects include upper respiratory tract infections, diarrhoea, constipation, nausea and vomiting.
Can I take Reglin during pregnancy or while breastfeeding?
Safety in pregnant women has not been established. Repaglinide should be used during pregnancy only if it is clearly needed. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Reglin?
In studies, patients who took up to 80 mg of Repaglinide had few adverse effects apart from a fall in blood glucose. When meals were given along with these high doses, hypoglycemia did not occur. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Reglin?
Store Repaglinide at a temperature no higher than 30°C. Keep it away from light, and make sure children can't reach it.
Can I take other medicines with Reglin?
Some medicines can interact with Repaglinide, for example: Clopidogrel Bisulphate, Carbamazepine, Chloramphenicol, Phenobarbital, Rifampicin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Reglin?
Reglin is a prescription (Rx) medicine. Take it as your doctor advises.