Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Reelife DS is indicated for:
Pharmacology
Amitriptyline belongs to the tricyclic antidepressant group, while Chlordiazepoxide is an anxiolytic. Amitriptyline works by blocking the reuptake of norepinephrine and serotonin in the brain, and it is this action that accounts for its antidepressant effect. Chlordiazepoxide, on the other hand, boosts GABA-mediated chloride influx through GABA receptor channels, which hyperpolarizes the cell membrane. Together, these neuro-inhibitory actions produce the sedative and anxiolytic effects seen with this combination.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Optimum dosage varies with the severity of the symptoms and the response of the individual patient. When a satisfactory response is obtained, the dosage should be reduced to the smallest amount needed to maintain the remission. The larger portion of the total daily dose may be taken at bedtime. In some patients, a single dose at bedtime may be sufficient. An initial dosage of 3 or 4 tablets daily in divided doses is generally satisfactory, or as directed by the physician.
Side Effects
Side effects: Treatment with Limitrol has been linked to several symptoms that also occur commonly in depression itself, including loss of appetite, tiredness, weakness, restlessness and sluggishness. Adverse reactions: The most frequently reported reactions are drowsiness, dry mouth, constipation, blurred vision, dizziness and bloating. Less commonly, patients have experienced vivid dreams, impotence, tremor, confusion and a stuffy nose.
Cautions & Contraindications
Warnings & Precautions
Use with caution in patients who have had seizures in the past. If Limitrol is prescribed for someone with an overactive thyroid, or who is already on thyroid medication, they should be monitored closely. The usual care should be taken when treating patients whose kidney or liver function is impaired. Children and adolescents being treated with antidepressants, for any reason, should be watched carefully for signs of worsening symptoms, suicidal thoughts, or unusual changes in behavior.
Contraindications
This medicine is not suitable for anyone who is hypersensitive to benzodiazepines or tricyclic antidepressants. It should also not be taken together with a monoamine oxidase inhibitor.
Pregnancy & Breastfeeding
Safety during pregnancy and breastfeeding has not been established for this preparation.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Pediatric Use
Safety and effectiveness of Chlordiazepoxide and Amitriptyline Hydrochloride Tablets have not been established in the pediatric population. Anyone thinking of using these tablets in a child or adolescent must weigh the possible risks against the clinical need.
Geriatric Use
In elderly and debilitated patients, the dose should be kept to the smallest effective amount. This helps prevent ataxia, over sedation, confusion or anticholinergic effects.
Overdose
Deaths can happen with an overdose of this class of drugs. In an Amitriptyline overdose, the serious signs are cardiac dysrhythmias, severe hypotension, convulsions and CNS depression, which can go as far as coma. An overdose of the benzodiazepine part shows up as somnolence, confusion, coma and diminished reflexes.
Stopping Chlordiazepoxide suddenly has led to withdrawal symptoms, similar in character to those seen with barbiturates and alcohol. These include convulsions, tremor, abdominal and muscle cramps, vomiting and sweating. Milder withdrawal symptoms, such as dysphoria and insomnia, have generally been reported when benzodiazepines taken continuously at therapeutic levels for several months are stopped abruptly. Abrupt discontinuation of Amitriptyline has also been linked to withdrawal symptoms, for example nausea, headache and malaise.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Amitriptyline Hydrochloride + Chlordiazepoxide in a cool, dry place, away from light. And as with all medicines, keep it out of the reach of children.
Common questions about Reelife DS 25 mg+10 mg
What is Reelife DS 25 mg+10 mg Tablet?
Reelife DS 25 mg+10 mg Tablet is a medicine that contains Amitriptyline Hydrochloride + Chlordiazepoxide. It is made by Eskayef Pharmaceuticals Ltd. It belongs to the Combined anxiolytics & anti-depressant drugs group of medicines.
What is Reelife DS used for?
Reelife DS is used for: Depression, Anxiety, Insomnia.
What are the side effects of Reelife DS?
Side effects: Treatment with Limitrol has been linked to several symptoms that also occur commonly in depression itself, including loss of appetite, tiredness, weakness, restlessness and sluggishness. Adverse reactions: The most frequently reported reactions are drowsiness, dry mouth, constipation, blurred vision, dizziness and bloating.
Can I take Reelife DS during pregnancy or while breastfeeding?
Safety during pregnancy and breastfeeding has not been established for this preparation. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Reelife DS?
Deaths can happen with an overdose of this class of drugs. In an Amitriptyline overdose, the serious signs are cardiac dysrhythmias, severe hypotension, convulsions and CNS depression, which can go as far as coma. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Reelife DS?
Keep Amitriptyline Hydrochloride + Chlordiazepoxide in a cool, dry place, away from light. And as with all medicines, keep it out of the reach of children.
Is there a cheaper medicine with the same ingredient?
Reelife DS is already among the lowest-priced brands of Amitriptyline Hydrochloride + Chlordiazepoxide at this strength.
Do I need a prescription for Reelife DS?
Reelife DS is a prescription (Rx) medicine. Take it as your doctor advises.