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Raditil FC Tablet

Rx

20 mg • Tablet

Tenoxicam • Radiant Pharmaceuticals Ltd.

Therapeutic class: Drugs for Osteoarthritis

🌐 বাংলায় দেখুন

Available as: 20 mg

Indications & Uses

Raditil FC Tablet is indicated for:

Pharmacology

Tenoxicam is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties, and it also inhibits platelet aggregation. It works by inhibiting prostaglandin biosynthesis. In-vitro tests of leukocyte peroxidase suggest that Tenoxicam may act as a scavenger for active oxygen at the site of inflammation. It is also a potent in-vitro inhibitor of the human metalloproteinases stromelysin and collagenase, enzymes that drive cartilage breakdown. Together, these effects help explain the therapeutic benefit of Tenoxicam in treating painful inflammatory and degenerative disorders of the musculoskeletal system. In animal studies, Tenoxicam showed no mutagenic, carcinogenic or teratogenic effects. However, as with other prostaglandin inhibitors, animal safety studies noted renal and gastrointestinal effects, along with an increased incidence of dystocia and delayed parturition.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Dosage

Standard dosage: Except for acute gout, the usual dose is 20 mg once daily, taken at the same time each day.

Acute gout: 40 mg once daily for the first two days, then 20 mg once daily for the next five days.

Chronic conditions: Tenoxicam starts working early in treatment, with the response building gradually over time. Daily doses above 20 mg should be avoided in chronic conditions, as this raises the risk of side effects without adding meaningful benefit. For patients who need long-term treatment, the dose may later be reduced to 10 mg once daily for maintenance.

Special populations: These same dosage guidelines generally apply to elderly patients and to those with kidney or liver disease. No dosage has been established for children and adolescents, as clinical experience in these age groups is lacking.

Side Effects

Based on data from clinical trials involving large numbers of patients, Inoten has proved to be well tolerated at the recommended dose, with the undesirable effects reported usually mild and temporary. In only a small proportion of patients was it necessary to stop treatment because of side effects, and local tolerance of Inoten given by injection was good. Effects occurring in more than 1% of patients include gastric, epigastric and abdominal discomfort, dyspepsia, heartburn and nausea affecting the gastrointestinal tract, along with dizziness and headache affecting the central nervous system. Effects occurring in less than 1% of patients include, in the gastrointestinal tract, constipation, diarrhea, stomatitis, gastritis, vomiting, ulcers and gastrointestinal bleeding including hematemesis and melena; in the central nervous system, fatigue, sleep disturbances, loss of appetite, dry mouth and vertigo; in the skin, itching (also in the anal region after rectal use), redness, rash-like eruptions, rash and urticaria; in the urinary tract and kidneys, a rise in BUN or creatinine and edema; in the liver and biliary tract, raised liver enzyme activity; and in the cardiovascular system, palpitations. Isolated cases, occurring in fewer than 0.01% of patients, include gastrointestinal perforation; visual disturbances affecting the central nervous system; Stevens-Johnson syndrome, Lyell's syndrome, photosensitivity reactions and vasculitis affecting the skin; anemia, agranulocytosis, leukopenia and thrombocytopenia affecting the blood; hypersensitivity reactions such as difficulty breathing, asthma, anaphylaxis and angioedema; elevated blood pressure, seen mainly in patients also taking cardiovascular drugs; and hepatitis affecting the liver and biliary tract.

Cautions & Contraindications

Warnings & Precautions

NSAIDs inhibit renal prostaglandin synthesis and consequently may have an undesirable effect on renal hemodynamics and on salt and water balance. It is necessary to adequately monitor the patient, with special emphasis on cardiac and renal function (BUN, creatinine, development of edema, weight gain, etc.), when giving Inoten to patients with conditions that could increase their risk of developing renal failure, such as pre-existing renal disease, impaired renal function in diabetics, hepatic cirrhosis, congestive heart failure, volume depletion, or concomitant treatment with potentially nephrotoxic drugs, diuretics, and corticosteroids. Inoten inhibits platelet aggregation and may affect hemostasis. Inoten has no significant influence on blood coagulation factors, coagulation time, prothrombin time, or activated thromboplastin time. Patients having coagulation disorders or receiving drug therapy that interferes with hemostasis should, however, be carefully observed when Inoten is administered. Any patient being treated with Inoten who presents with symptoms of gastrointestinal disease should be closely monitored. If peptic ulceration or gastrointestinal bleeding occurs, Inoten should be withdrawn immediately. If severe skin reactions, such as Lyell's syndrome or Stevens-Johnson syndrome, occur, treatment should be discontinued immediately. Adverse eye findings have been reported with Inoten, so ophthalmic evaluation is recommended for patients who develop visual disturbances. Because of the high plasma protein binding of Inoten, caution is required when plasma albumin levels are markedly reduced. As with anti-inflammatory drugs in general, Inoten may mask the usual signs of infection. Inoten tablets should not be given to patients who either dislike or do not tolerate milk products.

Contraindications

Tenoxicam should not be given to anyone who is hypersensitive to it, or who has previously developed asthma, rhinitis, or urticaria after taking aspirin or other NSAIDs. It is also unsuitable for patients with a current or past history of upper gastrointestinal disease, such as gastritis or gastric and duodenal ulcers.

Pregnancy & Breastfeeding

NSAIDs inhibit prostaglandin synthesis and, when used late in pregnancy, may cause premature closure of the fetal ductus arteriosus, prolong labor and delay delivery. Treatment during the third trimester should be avoided. Single-dose studies show that only a very small amount of tenoxicam, about 0.2 percent, passes into breast milk, and no adverse effects have been reported in breast-fed infants of mothers taking Tenoxicam. Even so, infants should be weaned or the drug discontinued.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Use in Special Populations

Use in children and adolescents

Oxicam is not recommended for patients under 16 years of age, because the dose and indications in this age group have not been established.

Effects on ability to drive and use machines

Some patients get adverse events such as vertigo, dizziness or visual disturbances. If this happens to you, don't drive a car or use machines.

Overdose

No one has reported an acute overdose of Oxicam so far. Even so, the signs and symptoms listed under Undesirable effects would be expected to be more pronounced if it happened. Overdose should be treated with the usual measures to reduce absorption (for example gastrolavage and charcoal) and to speed up elimination (for example cholestyramine).

⚠️ In an emergency call 999 or go to the nearest hospital emergency department.

Storage

Store Tenoxicam at a temperature not above 30°C. Protect it from light and moisture, and keep it out of the reach of children.

Drug Interactions

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Moderate Digoxin

Moderate Glibenclamide

Moderate Methotrexate

Moderate Cimetidine

Moderate Warfarin Sodium

Minor Atenolol

Minor Hydrochlorothiazide

Minor Furosemide

Minor Penicillamine

Minor Heparin Sodium

Common questions about Raditil FC Tablet 20 mg

What is Raditil FC Tablet 20 mg Tablet?

Raditil FC Tablet 20 mg Tablet is a medicine that contains Tenoxicam. It is made by Radiant Pharmaceuticals Ltd. It belongs to the Drugs for Osteoarthritis group of medicines.

What is Raditil FC Tablet used for?

Raditil FC Tablet is used for: Osteoarthritis, Rheumatoid Arthritis, Gout.

What are the side effects of Raditil FC Tablet?

Based on data from clinical trials involving large numbers of patients, Inoten has proved to be well tolerated at the recommended dose, with the undesirable effects reported usually mild and temporary. In only a small proportion of patients was it necessary to stop treatment because of side effects, and local tolerance of Inoten given by injection was good.

Can I take Raditil FC Tablet during pregnancy or while breastfeeding?

NSAIDs inhibit prostaglandin synthesis and, when used late in pregnancy, may cause premature closure of the fetal ductus arteriosus, prolong labor and delay delivery. Treatment during the third trimester should be avoided. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

What happens if I take too much Raditil FC Tablet?

No one has reported an acute overdose of Oxicam so far. Even so, the signs and symptoms listed under Undesirable effects would be expected to be more pronounced if it happened. In an emergency call 999 or go to the nearest hospital emergency department.

How should I store Raditil FC Tablet?