Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Q-late is indicated for:
Pharmacology
6s-5-methyltetrahydrofolate is a water-soluble vitamin B. In the body it works as a coenzyme or co-substrate in making DNA and RNA and in the metabolism of amino acids. Deficiency is common during pregnancy, and it may lead to fetal malformations such as neural tube defects. Inadequate maternal folate status has also been linked with low infant birth weight, preterm delivery and fetal growth retardation. Spina bifida and anencephaly are the most common neural tube defects (NTDs). Folic acid supplementation before conception and during the first trimester has been shown to reduce the recurrence of NTDs in women. Supplementation is used to treat megaloblastic anemia during pregnancy. 68-5-methyltetrahydrofolate is a fourth generation folate derivative, a new generation of folic acid derivative made up of 6S-5-methyltetrahydrofolate and glucosamine salt. It is readily active and has the added advantage of higher bioavailability, safety and stability.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Take 1 to 2 capsules a day, or as your doctor directs.
Side Effects
6s-5-Methyltetrahydrofolate [Bio-Active Folate] is generally well tolerated. Stomach and bowel upsets and allergic reactions have been reported, but only rarely. High doses can cause the following effects. Gastrointestinal disorders: anorexia, diarrhea, nausea, abdominal distension and flatulence. Hypersensitivity reactions: allergic reactions, including erythema, rash, pruritus, urticaria, and anaphylactic reactions (including shock).
Cautions & Contraindications
Warnings & Precautions
Folic acid on its own is not enough to treat pernicious anemia, or other megaloblastic anemias where Vitamin B12 is deficient. In doses above 0.1 mg daily, folic acid may hide pernicious anemia, because the blood picture can go into remission (hematologic remission) while the neurological problems keep getting worse. When this nutritional supplement is prescribed for pregnant women, nursing mothers or women before conception, their medical condition should be considered, along with any drugs, herbs and/or supplements they are taking.
Contraindications
Patients who are known to be hypersensitive to 6s-5-methyltetrahydrofolate, or to any of the other ingredients in the product, should not take it.
Pregnancy & Breastfeeding
Folic acid is considered safe and acceptable to use in pregnancy. It is actively secreted into breast milk. A breastfeeding mother may need supplements if poor eating habits have left her deficient and led to megaloblastic anemia. The American Academy of Pediatrics considers folic acid compatible with breast feeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
If you take too much of this medicine by accident, call a doctor or go to a hospital straight away.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep this medicine in a dry place, below 25°C, and away from light. Keep it out of reach of children.
Drug Interactions
Common questions about Q-late 400 mcg
What is Q-late 400 mcg Capsule?
Q-late 400 mcg Capsule is a medicine that contains 6s-5-Methyltetrahydrofolate [Bio-Active Folate]. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Herbal and Nutraceuticals group of medicines.
What is Q-late used for?
Q-late is used for: Epilepsy, Alzheimer's Disease, Depression.
What are the side effects of Q-late?
6s-5-Methyltetrahydrofolate [Bio-Active Folate] is generally well tolerated. Stomach and bowel upsets and allergic reactions have been reported, but only rarely.
Can I take Q-late during pregnancy or while breastfeeding?
Folic acid is considered safe and acceptable to use in pregnancy. It is actively secreted into breast milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Q-late?
If you take too much of this medicine by accident, call a doctor or go to a hospital straight away. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Q-late?
Keep this medicine in a dry place, below 25°C, and away from light. Keep it out of reach of children.
Can I take other medicines with Q-late?
Some medicines can interact with 6s-5-Methyltetrahydrofolate [Bio-Active Folate], for example: Nitrofurantoin, Pyrimethamine, Primidone, Folate, Phenytoin, Folic Acid. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Q-late is already among the lowest-priced brands of 6s-5-Methyltetrahydrofolate [Bio-Active Folate] at this strength.
Do I need a prescription for Q-late?
Q-late is a prescription (Rx) medicine. Take it as your doctor advises.