Pricing
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Pires-D is indicated for:
Pharmacology
Dextromethorphan Hydrobromide is a non-opioid antitussive. It works on the cough center in the medulla oblongata and raises the threshold for the cough reflex, so the cough is triggered less easily. Levomenthol has mild local anesthetic and decongestant properties. Diphenhydramine Hydrochloride has antitussive, antihistaminic and anticholinergic properties.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and children over 12 years can take 2 teaspoonfuls of the syrup 4 times a day, or as the physician directs. Don't take more than 8 teaspoonfuls of syrup in 24 hours.
Use in children and adolescents: the efficacy and safety of Dextromethorphan Hydrobromide have not been established in pediatric patients and adolescents.
Side Effects
This syrup may cause drowsiness, dizziness, nausea, vomiting, an upset stomach, and a dry mouth, nose and throat. Some people also have difficulty passing urine or blurred vision.
Cautions & Contraindications
Warnings & Precautions
This syrup can make you drowsy. If it does, don't drive or operate machinery. People with narrow-angle glaucoma or symptomatic prostatic hypertrophy should not take Diphenhydramine Hydrochloride. Take particular care in adolescents and young adults, and in patients with a history of drug abuse or of using psychoactive substances.
Contraindications
Don't give this syrup to anyone who is known to be hypersensitive to the product or to any of its components. It must also not be used by people who are taking a monoamine oxidase inhibitor, or who have taken one within the preceding two weeks. Dextromethorphan, like other centrally acting antitussive agents, should not be given to people who are in respiratory failure or at risk of developing it.
Pregnancy & Breastfeeding
Pregnancy: Diphenhydramine Hydrochloride and Dextromethorphan Hydrobromide have both been used widely for many years, and no clear harm has been seen. Even so, there isn't enough information about what Dextromethorphan Hydrobromide does when it is given during human pregnancy.
Lactation: Nobody knows whether dextromethorphan or its metabolites pass into breast milk. Diphenhydramine Hydrochloride is known to cross the placenta, and it has also been found in breast milk. For this reason, the syrup should only be used when the benefit of treatment to the mother is greater than any possible risk to the developing fetus or the suckling infant.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Higher doses can cause hallucinations and convulsions, and children are particularly at risk. With massive doses, the person may go into coma or cardiovascular collapse.
Treatment of overdose is symptomatic and supportive. Measures that bring about rapid gastric emptying may be useful, and so may activated charcoal in cases of acute poisoning. Naloxone has been used successfully in children as a specific antagonist to dextromethorphan toxicity. Convulsions may be controlled with diazepam and thiopental sodium.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep this medicine in a dry place, at a temperature not above 30°C. Protect it from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Pires-D 14 mg+6.5 mg+2 mg
What is Pires-D 14 mg+6.5 mg+2 mg Syrup?
Pires-D 14 mg+6.5 mg+2 mg Syrup is a medicine that contains Diphenhydramine + Dextromethorphan + Levomenthol. It is made by Navana Pharmaceuticals Ltd. It belongs to the Combined cough expectorants group of medicines.
What is Pires-D used for?
Pires-D is used for: Cough.
What are the side effects of Pires-D?
This syrup may cause drowsiness, dizziness, nausea, vomiting, an upset stomach, and a dry mouth, nose and throat. Some people also have difficulty passing urine or blurred vision.
Can I take Pires-D during pregnancy or while breastfeeding?
Pregnancy: Diphenhydramine Hydrochloride and Dextromethorphan Hydrobromide have both been used widely for many years, and no clear harm has been seen. Even so, there isn't enough information about what Dextromethorphan Hydrobromide does when it is given during human pregnancy. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Pires-D?
Higher doses can cause hallucinations and convulsions, and children are particularly at risk. With massive doses, the person may go into coma or cardiovascular collapse. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Pires-D?
Keep this medicine in a dry place, at a temperature not above 30°C. Protect it from light and moisture.
Can I take other medicines with Pires-D?
Some medicines can interact with Diphenhydramine + Dextromethorphan + Levomenthol, for example: Diphenhydramine Hydrochloride, Dextromethorphan Hydrobromide, Atropine Sulphate. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Pires-D?
Pires-D is a prescription (Rx) medicine. Take it as your doctor advises.