Pricing
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Phosphoprep is indicated for:
Pharmacology
Sodium phosphate is used to treat hypophosphataemia. It also works as a mild osmotic laxative, either taken by mouth as a dilute solution or given by the rectal route. For bowel cleansing before surgery or endoscopy procedures, phosphate enemas or concentrated oral solutions are used.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dose for bowel preparation, adults and children 5 years of age and over: the recommended dose of Sodium Dihydrogen Phosphate + Disodium Hydrogen Phosphate is 45 ml, repeated 10 to 12 hours later. Clear liquids are an essential part of this regimen. On the day before the procedure, the patient should take only clear liquids for breakfast, lunch and dinner and between doses. No solid food, milk or milk products should be taken that day, and the patient should not drink anything coloured red or purple. The procedure may be done in the early morning, mid-morning or later, so there are two alternative dosage regimens. For an early morning procedure, the first dose is taken at 7 a.m. on the morning before the procedure and the second dose at 7 p.m. on the evening before the procedure. For a mid-morning (or later) procedure, the first dose is taken at 7 p.m. on the evening before the procedure and the second dose at 7 a.m. (or at least 3 hours before leaving for the appointment) on the morning before the procedure. First dose: mix 15 ml (one third of the bottle) of Sodium Dihydrogen Phosphate + Disodium Hydrogen Phosphate into a full glass (approximately 250 ml) of clear liquids and drink it. Repeat this two more times within the next 20 minutes. Between doses: between the first and second doses, the patient should drink at least three more glasses (approximately 250 ml each) of clear liquids, or more if desired, to prevent dehydration and to ensure that the bowel remains easily examinable for the procedure. Second dose: mix 15 ml into a full glass of clear liquid and drink it. Repeat this two more times within the next 20 minutes. Please refer to the clear liquids list below. Beverages, water, tea or coffee (no milk or non dairy creamer) and sweeteners are acceptable. Carbonated or non carbonated soft drinks (not coloured red or purple), fruit flavoured cordials (not coloured red or purple) and strained fruit juices without pulp are also acceptable. Do not drink any alcoholic beverage. Dose for occasional constipation: 12 years old, 20 to 45 ml. 10 to 11 years old child, 10 to 20 ml. 5 to 9 years old child, 5 to 10 ml.
Side Effects
With Sodium Dihydrogen Phosphate + Disodium Hydrogen Phosphate (also called sodium biphosphate and sodium phosphate), the common effects are in the stomach and gut. Bloating has been reported in 31% to 41% of people, nausea in 26% to 30%, abdominal pain in 23% to 25%, and vomiting in 4% to 9%. Effects on the nervous system have included dizziness, headache and seizures. Kidney problems have included renal impairment, increased blood urea nitrogen (BUN), increased creatinine, acute renal failure, acute phosphate nephropathy, nephrocalcinosis and renal tubular necrosis. Hypersensitivity reactions have also been reported. These include anaphylaxis, rash, pruritus, urticaria, throat tightness, bronchospasm and dyspnea.
Cautions & Contraindications
Warnings & Precautions
Use this solution with extreme caution in the elderly, in frail or weak patients, in patients with a colostomy, and in patients on a low salt diet, because these people are particularly at risk. They should drink extra fluids both before and after the solution is given, so that dehydration does not happen. Some patients are having major bowel procedures and are kept nil by mouth for long periods. Their electrolytes should be monitored, and before surgery they should receive intravenous fluids containing potassium and calcium. Be careful too in patients who take diuretics, and in patients who use medicines known to prolong the QT interval. Polyethylene glycol bowel cleansing preparations should not be given together with this solution, as the combination may be dangerous. Patients should also be told not to use the solution when nausea, vomiting or abdominal pain is present, unless a physician directs them to.
Contraindications
Don't use this enema if you have CHF, renal failure or clinically significant impaired renal function, congenital or acquired megacolon, bowel or GI obstruction, ascites, perforation of ileus, or active inflammatory bowel disease.
Pregnancy & Breastfeeding
Use in pregnancy: Sodium Dihydrogen Phosphate + Disodium Hydrogen Phosphate is not recommended for pregnant women, because the phosphate can be absorbed and cross the placenta, which could harm the baby. It should be used only if the likely benefit to the mother is greater than the possible risk.
Use in lactation: Phosphate can pass into breast milk and may harm the breastfed infant, so this product is not recommended for nursing mothers. The same rule applies here, and it should be used only if the likely benefit outweighs the possible risk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Use in children: Sodium Dihydrogen Phosphate + Disodium Hydrogen Phosphate should not be given to children under 5 years of age.
Use in diabetics:
The liquid diet taken during the period of administration, and before bowel surgery, X-ray of the colon or colonoscopy, may affect the blood glucose levels of diabetic patients. So their insulin or oral anti-diabetic medicine may need to be adjusted.
Storage
Keep this medicine in a cool, dry place, away from light. Keep it out of children's reach.
Drug Interactions
Common questions about Phosphoprep 2.711 gm+1.2 gm
What is Phosphoprep 2.711 gm+1.2 gm Oral Solution?
Phosphoprep 2.711 gm+1.2 gm Oral Solution is a medicine that contains Sodium Dihydrogen Phosphate + Disodium Hydrogen Phosphate. It is made by Unimed Unihealth Pharmaceuticals Ltd. It belongs to the Enema & bowel cleansing solution group of medicines.
What is Phosphoprep used for?
Phosphoprep is used for: Constipation.
What are the side effects of Phosphoprep?
With Sodium Dihydrogen Phosphate + Disodium Hydrogen Phosphate (also called sodium biphosphate and sodium phosphate), the common effects are in the stomach and gut. Bloating has been reported in 31% to 41% of people, nausea in 26% to 30%, abdominal pain in 23% to 25%, and vomiting in 4% to 9%.
Can I take Phosphoprep during pregnancy or while breastfeeding?
Use in pregnancy: Sodium Dihydrogen Phosphate + Disodium Hydrogen Phosphate is not recommended for pregnant women, because the phosphate can be absorbed and cross the placenta, which could harm the baby. It should be used only if the likely benefit to the mother is greater than the possible risk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Phosphoprep?
Keep this medicine in a cool, dry place, away from light. Keep it out of children's reach.
Can I take other medicines with Phosphoprep?
Some medicines can interact with Sodium Dihydrogen Phosphate + Disodium Hydrogen Phosphate, for example: Polyethylene Glycol. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Phosphoprep?
Phosphoprep is a prescription (Rx) medicine. Take it as your doctor advises.