Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Peptofit is indicated for:
Pharmacology
Antacid action: Bismuth Subsalicylate coats the ulcer surface and protects it from acid and pepsin. It stimulates mucus and bicarbonate secretion. It also reacts with HCl to produce bismuth oxychloride and salicylic acid, which together reduce HCl.
Anti-diarrheal action: Bismuth Subsalicylate stimulates the absorption of water and electrolytes across the intestinal wall. In infectious diarrhea, it binds with the toxin produced by E.coli and disrupts the cell, causing lysis of H.pylori. It also prevents H.pylori from adhering to the cell wall of the intestine.
Anti-inflammatory action: When it is hydrolyzed to salicylic acid, Bismuth Subsalicylate inhibits prostaglandin G/H synthase ½. This reduces inflammation. It also coats the irritated tissue to slow the expulsion of fluid.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For adults over 16, the dose is 30 ml, measured in the dosing cup that comes with the medicine, or 6 spoonfuls of 5 ml each. Children aged 10 to 14 years should take 15 mL (3 teaspoons), and children aged 5 to 9 years should take 7.5 mL (1.5 teaspoons). For children aged 3 to 4 years, the dose is 5 mL (1 teaspoon). Children under 3 years should not be given it without asking a doctor first.
Older people don't need any special precaution. If the patient has renal insufficiency, caution should be taken.
The dose can be repeated every ½ to 1 hour if needed. However, no more than 8 doses should be taken in 24 hours.
Side Effects
Black stool and a darkened (black) tongue are common with the use of Pink-Bismol. Pink-Bismol should not be used if symptoms are severe or persist for more than 2 days. Do not exceed the recommended dose, and shake the bottle well before each use. For oral use only.
Cautions & Contraindications
Warnings & Precautions
Do not take this medicine together with aspirin or other salicylates. Patients taking anticoagulant medicines (blood thinners), or medicines for diabetes or gout, should use it with caution.
Contraindications
Bismuth subsalicylate must not be taken by anyone who is allergic to aspirin, other salicylates, or any ingredient in this product. Keep all medicines out of the reach and sight of children.
Pregnancy & Breastfeeding
Pregnancy: There isn't enough reliable data on using bismuth subsalicylate during pregnancy, and animal studies haven't clearly shown how it affects pregnancy, the developing baby, delivery, or development after birth. Because of this, its risk to humans isn't known.
Breastfeeding: It's best to avoid bismuth subsalicylate while breastfeeding unless your doctor determines it's genuinely needed.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Bismuth Subsalicylate intoxication can show up as an acute encephalopathy, with confusion, myoclonic movements, tremor, dysarthria, and problems with walking and standing. It may also cause gastrointestinal disturbances, skin reactions, discoloration of the mucous membranes, and renal dysfunction from acute tubular necrosis.
Treatment includes gastric lavage, purgation and hydration. Chelating agents may work in the early stages after ingestion, and haemodialysis may be necessary.
An overdose of Bismuth Subsalicylate may also give symptoms of salicylate intoxication, such as dizziness, tinnitus, sweating, nausea and headache. If any of these symptoms occur, stop using Bismuth Subsalicylate. Management of the overdose is the same as for salicylate overdose.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Bismuth Subsalicylate below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Common questions about Peptofit 87.5 mg/5 ml
What is Peptofit 87.5 mg/5 ml Oral Suspension?
Peptofit 87.5 mg/5 ml Oral Suspension is a medicine that contains Bismuth Subsalicylate. It is made by Opsonin Pharma Limited.
What is Peptofit used for?
Peptofit is used for: Gastroesophageal Reflux Disease, Dyspepsia, Diarrhea, Nausea and Vomiting.
What are the side effects of Peptofit?
Black stool and a darkened (black) tongue are common with the use of Pink-Bismol. Pink-Bismol should not be used if symptoms are severe or persist for more than 2 days.
Can I take Peptofit during pregnancy or while breastfeeding?
Pregnancy: There isn't enough reliable data on using bismuth subsalicylate during pregnancy, and animal studies haven't clearly shown how it affects pregnancy, the developing baby, delivery, or development after birth. Because of this, its risk to humans isn't known. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Peptofit?
Bismuth Subsalicylate intoxication can show up as an acute encephalopathy, with confusion, myoclonic movements, tremor, dysarthria, and problems with walking and standing. It may also cause gastrointestinal disturbances, skin reactions, discoloration of the mucous membranes, and renal dysfunction from acute tubular necrosis. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Peptofit?
Store Bismuth Subsalicylate below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Do I need a prescription for Peptofit?
Peptofit is a prescription (Rx) medicine. Take it as your doctor advises.