P

Parkin

Rx

10 mg • Injection

Procyclidine Hydrochloride • Popular Pharmaceuticals PLC

Therapeutic class: Antiparkinson drugs

🌐 বাংলায় দেখুন

Available as: 10 mg

More from Parkin

Other strengths and forms by Popular Pharmaceuticals PLC

Parkin 5 mg Tablet

Indications & Uses

Kdrin is used as an adjunctive treatment for all forms of parkinsonian syndrome. It is mainly used for the symptomatic treatment of idiopathic (paralysis agitans), postencephalitic and arteriosclerotic parkinsonism. It is also used to control troublesome extrapyramidal symptoms, including pseudoparkinsonism, acute dystonic reactions, and akathisia induced by neuroleptic drugs such as phenothiazine derivatives.

Pharmacology

Procyclidine hydrochloride is an antimuscarinic medicine used to treat Parkinson's disease, and it carries relatively low toxicity. It is a synthetic tertiary amine. The drug works by correcting the relative excess of cholinergic activity that is thought to occur in Parkinson's disease as a result of reduced dopamine levels. It is absorbed from the gastrointestinal tract and clears from body tissues fairly quickly. When given intravenously, it starts working within 5 to 20 minutes, and its effects last for up to 4 hours.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

For Injection

5 to 10 mg, which may be repeated after 20 minutes if necessary, up to a maximum of 20 mg a day.

Dosage for other forms (1)

Tablet

Give by mouth, preferably after meals. For parkinsonism, start with 2.5 mg three times a day, then increase to 5 mg three times a day, with an occasional 5 mg dose at bedtime. Adjust the dose as tolerated until the total daily amount reaches 20 to 30 mg, split into 3 to 4 doses. For drug induced extrapyramidal symptoms, start with 2.5 mg three times a day, then raise the dose by 2.5 mg increments per day as needed and tolerated.

Side Effects

Dryness of the mouth is the effect most patients notice, and at normal doses it's usually all they'll experience. Some people also get blurred vision or wider pupils, or digestive troubles such as nausea, vomiting, constipation, or discomfort in the upper abdomen. An allergic reaction like a skin rash, or a feeling of muscle weakness, is possible but not common. At higher doses, dizziness can occur, and in some cases confusion or hallucinations. Taking the medicine after meals and having the dose adjusted as needed can help keep these effects to a minimum.

Cautions & Contraindications

Warnings & Precautions

Precaution should be taken in cases of hepatic and renal impairment, and in children, the elderly, and pregnant or breastfeeding women. Patients with mental disorders occasionally experience a precipitation of a psychotic episode when Kdrin is administered for the treatment of extrapyramidal side effects caused by neuroleptics. Kdrin should not be withdrawn abruptly, as rebound Parkinsonism symptoms may occur.

Contraindications

Caution is advised when giving Procyclidine to children and elderly patients. It should also be used carefully in patients with diarrhoea, cardiovascular disease, glaucoma, urinary retention, or impaired liver or kidney function. Its safety during pregnancy has not been established, and it is not known whether it passes into breast milk.

Pregnancy & Breastfeeding

Because procyclidine may be used during pregnancy or while breastfeeding, and in women who could become pregnant, the doctor and patient should weigh the potential benefits against the possible risks to both mother and child before it is used.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Use in Special Populations

Use in children: Safety and efficacy of Procyclidine Hydrochloride haven't been established in children. So if a doctor considers it for a child, the possible benefits have to be weighed against the possible hazards to that child.

Storage

Keep Procyclidine Hydrochloride away from light and moisture, and store it below 25°C. Keep it out of the reach of children.

Drug Interactions

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Moderate Ketoconazole

Moderate Amantadine Hydrochloride

Common questions about Parkin 10 mg

What is Parkin 10 mg Injection?

Parkin 10 mg Injection is a medicine that contains Procyclidine Hydrochloride. It is made by Popular Pharmaceuticals PLC. It belongs to the Antiparkinson drugs group of medicines.

What is Parkin used for?

Kdrin is used as an adjunctive treatment for all forms of parkinsonian syndrome. It is mainly used for the symptomatic treatment of idiopathic (paralysis agitans), postencephalitic and arteriosclerotic parkinsonism.

What are the side effects of Parkin?

Dryness of the mouth is the effect most patients notice, and at normal doses it's usually all they'll experience. Some people also get blurred vision or wider pupils, or digestive troubles such as nausea, vomiting, constipation, or discomfort in the upper abdomen.

Can I take Parkin during pregnancy or while breastfeeding?

Because procyclidine may be used during pregnancy or while breastfeeding, and in women who could become pregnant, the doctor and patient should weigh the potential benefits against the possible risks to both mother and child before it is used. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

How should I store Parkin?