O

Ozil 5

Rx

5 mg • Tablet

Olanzapine • Goodman Pharmaceuticals Ltd

Therapeutic class: Atypical neuroleptic drugs

🌐 বাংলায় দেখুন

Available as: 5 mg

Indications & Uses

Ozil 5 is indicated for:

Pharmacology

Olanzapine is an antipsychotic medicine. It acts on a broad range of receptors in the brain, including serotonin receptors (5HT2A/2C, 5HT3, 5HT6), dopamine receptors (D1, D2, D3, D4, D5), the M1-M5 cholinergic muscarinic receptors, α1 adrenergic receptors, and histamine H1 receptors. As with other medicines used in schizophrenia, exactly how Olanzapine works is not fully understood, but its benefit is thought to come mainly from blocking dopamine and serotonin type 2 (5HT2) activity together. Taken by mouth, it is absorbed well and reaches its highest levels in the blood after 5 to 8 hours; food does not affect this absorption. Studies have not found Olanzapine to cause mutations, chromosome damage, or cancer.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Schizophrenia, combination therapy for mania, and bipolar disorder

For these uses, Olanzapine is started at 5 to 10 mg once daily. The daily dose can then be adjusted according to the person's clinical condition, anywhere between 5 and 20 mg a day. A dose above 10 mg daily should only be given after reassessment. The maximum is 20 mg daily.

Monotherapy for mania

Here the starting dose is 15 mg once daily. Later on, the daily dose can be adjusted according to the person's clinical condition, between 5 and 20 mg a day. A dose above 15 mg should only be given after reassessment. The maximum is 20 mg daily.

Side Effects

Very common side effects include drowsiness and weight gain. Other effects that may occur include increased appetite, raised blood sugar and triglyceride levels, dizziness, restlessness (akathisia), Parkinson's-like symptoms, abnormal movements (dyskinesia), a drop in blood pressure on standing up (orthostatic hypotension), mild and temporary anticholinergic effects such as constipation and dry mouth, weakness, swelling (edema), and increased sensitivity to sunlight.

Cautions & Contraindications

Warnings & Precautions

Olzap should be used cautiously in patients with a history of seizures or with conditions that predispose to seizures. It should also be used cautiously in patients with low white blood cell and/or neutrophil counts from any cause, drug induced bone marrow suppression or toxicity from radiation therapy or chemotherapy, hypereosinophilic conditions, or impaired liver function, as well as in those taking hepatotoxic medicines, centrally acting drugs, or medicines known to prolong the QT interval, particularly in elderly patients. Patients should be warned about operating hazardous machinery, including driving.

Contraindications

Olanzapine should not be used by anyone who has a known hypersensitivity to any of its ingredients, or by patients who are at risk of narrow-angle glaucoma.

Pregnancy & Breastfeeding

Olanzapine should be used during pregnancy only when the possible benefits outweigh the possible risk to the foetus. Anyone taking olanzapine who becomes pregnant, or who plans to become pregnant, should tell their doctor. There is no report showing that olanzapine causes birth defects. People taking olanzapine should not breastfeed.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Use in Special Populations

Children: Olanzapine has not been studied in people under 18 years of age.

Elderly patients (age 65 and over): the starting dose is 5 mg/day.

Patients with hepatic or renal impairment: the starting dose is 5 mg/day.

Storage

Store Olanzapine below 30°C, away from light and moisture. Keep it out of the reach of children.

Drug Interactions

Open checker →

Moderate Carbamazepine

Moderate Rifampicin

Moderate Omeprazole

Moderate Activated Charcoal

Moderate Levodopa

Moderate Insulin Degludec

Moderate Dopamine Hydrochloride

Common questions about Ozil 5 5 mg

What is Ozil 5 5 mg Tablet?

Ozil 5 5 mg Tablet is a medicine that contains Olanzapine. It is made by Goodman Pharmaceuticals Ltd. It belongs to the Atypical neuroleptic drugs group of medicines.

What is Ozil 5 used for?

Ozil 5 is used for: Schizophrenia, Bipolar Disorder.

What are the side effects of Ozil 5?

Very common side effects include drowsiness and weight gain. Other effects that may occur include increased appetite, raised blood sugar and triglyceride levels, dizziness, restlessness (akathisia), Parkinson's-like symptoms, abnormal movements (dyskinesia), a drop in blood pressure on standing up (orthostatic hypotension), mild and temporary anticholinergic effects such as constipation and dry mouth, weakness, swelling (edema), and increased sensitivity to sunlight.

Can I take Ozil 5 during pregnancy or while breastfeeding?

Olanzapine should be used during pregnancy only when the possible benefits outweigh the possible risk to the foetus. Anyone taking olanzapine who becomes pregnant, or who plans to become pregnant, should tell their doctor. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

How should I store Ozil 5?