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Indications & Uses
Oxiconazole Nitrate topical preparation is used on the skin to treat three fungal infections: tinea pedis, tinea cruris and tinea corporis. These are caused by Trichophyton rubrum, Trichophyton mentagrophytes or Epidermophyton floccosum. Oxiconazole Nitrate Cream is also used to treat tinea (pityriasis) versicolor, which is caused by Malassezia furfur.
Pharmacology
This preparation contains Oxiconazole Nitrate, an antifungal medicine. It is for use on the skin only.
Oxiconazole Nitrate is an imidazole derivative. Its antifungal action comes mainly from blocking the making of ergosterol, which the fungal cell membrane needs to stay intact. In laboratory tests it works against many disease-causing fungi.
Oxiconazole has been shown to work against most strains of these organisms, both in the laboratory and in clinical infections at the indicated body sites: Epidermophyton floccosum, Trichophyton mentagrophytes, Trichophyton rubrum and Malassezia furfur.
It also shows satisfactory in vitro minimum inhibitory concentrations (MICs) against most strains of Microsporum audouini, Microsporum canis, Microsporum gypseum, Trichophyton tonsurans and Trichophyton violaceum.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Apply this preparation to the affected skin and the area right around it, once or twice a day, if you have tinea pedis, tinea corporis or tinea cruris. For tinea (pityriasis) versicolor, Oxiconazole Cream is applied once a day.
Treat tinea corporis, tinea cruris and tinea (pityriasis) versicolor for 2 weeks. Tinea pedis needs 1 month. The longer course for tinea pedis is there to reduce the chance of the infection coming back.
Side Effects
Oxiconazole Nitrate can cause itching, burning, irritation, allergic contact dermatitis, folliculitis, redness, papules, fissure, maceration, rash, stinging and nodules.
Cautions & Contraindications
Warnings & Precautions
Oxiconazole Nitrate topical preparation must not be used in the eyes or inside the vagina.
Contraindications
Oxiconazole topical preparations should not be used by anyone who has previously had a hypersensitivity reaction to Oxiconazole.
Pregnancy & Breastfeeding
Oxiconazole Nitrate is in pregnancy category B. The drug is excreted in human milk, so a nursing woman should use it with caution.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Oxiconazole Nitrate in a cool, dry place and away from light. Don't freeze it.
Common questions about Oxizol 1%
What is Oxizol 1% Cream?
Oxizol 1% Cream is a medicine that contains Oxiconazole Nitrate. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Topical Antifungal preparations group of medicines.
What is Oxizol used for?
Oxiconazole Nitrate topical preparation is used on the skin to treat three fungal infections: tinea pedis, tinea cruris and tinea corporis. These are caused by Trichophyton rubrum, Trichophyton mentagrophytes or Epidermophyton floccosum.
What are the side effects of Oxizol?
Oxiconazole Nitrate can cause itching, burning, irritation, allergic contact dermatitis, folliculitis, redness, papules, fissure, maceration, rash, stinging and nodules.
Can I take Oxizol during pregnancy or while breastfeeding?
Oxiconazole Nitrate is in pregnancy category B. The drug is excreted in human milk, so a nursing woman should use it with caution. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Oxizol?
Keep Oxiconazole Nitrate in a cool, dry place and away from light. Don't freeze it.
Do I need a prescription for Oxizol?
Oxizol is a prescription (Rx) medicine. Take it as your doctor advises.