Informational only — Not medical advice. Always consult a licensed healthcare provider.

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5%+1%
6 ml pack
৳60.00 per pack

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From ৳60.00 6 ml pack
Available as: 5%+1% · 6 ml pack

Indications & Uses

Rhubarb Extract + Salicylic Acid oral solution is used to treat acute and chronic inflammation of the lining (mucosa) of the mouth, gums and throat. This includes aphthous ulcer, cold sore, gingivitis, periodontitis, dental hypersensitivity, dental plaque and denture irritation.

Pharmacology

Salicylic acid in this preparation works by blocking cyclo-oxygenase, a substance in the body. The rhubarb extract contains anthraquinone glycosides, and these relieve inflammation. The preparation is well absorbed through the oral mucosa.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Adults should apply Rhubarb Extract + Salicylic Acid to the inflamed lining of the mouth, 3 to 4 times a day, using the brush provided. If you wear dentures, take them out first. After applying, don't rinse your mouth or eat for 15 minutes. Close the cap straight away after every use.

For children below the age of 12 years, use is recommended only after consulting a registered physician.

Side Effects

A short-lived burning feeling where the medicine is applied is very common with Rhubarb Extract + Salicylic Acid. Some people also notice temporary discoloration of the teeth or the lining of the mouth, which is commonly reported after using the oral solution.

Cautions & Contraindications

Warnings & Precautions

One bottle of the Rhubarb Extract + Salicylic Acid oral solution should be used by one person only.

Pregnancy & Breastfeeding

Pregnancy: There are not enough animal studies to say how Rhubarb Extract + Salicylic Acid affects pregnancy or the development of the embryo and foetus. The possible risk to humans is not known. Doctors should take care when prescribing it to pregnant women.

Lactation: Anthraquinone glycosides from rhubarb may pass into breast milk. At the usual therapeutic doses of the oral solution, though, it is not known whether these glycosides or salicylic acid pass into breast milk. Whether to continue breastfeeding or to continue the oral solution should be decided by weighing two things: the benefit of breastfeeding for the child and the benefit of the oral solution for the woman.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Overdose

An overdose from applying Rhubarb Extract + Salicylic Acid to the skin is unlikely, though nobody knows how much salicylic acid and how many anthraquinone derivatives actually get absorbed into the body. If the medicine is swallowed and the overdose becomes systemic, it might cause abdominal cramping and diarrhea. Salicylism is also possible, and it shows up as hyperventilation, tinnitus, deafness, vasodilation and sweating.

⚠️ In an emergency call 999 or go to the nearest hospital emergency department.

Storage

Keep Rhubarb Extract + Salicylic Acid in a cool, dry place, away from light.

Common questions about Orofresh OS 5%+1%

What is Orofresh OS 5%+1% Oral Solution?

Orofresh OS 5%+1% Oral Solution is a medicine that contains Rhubarb Extract + Salicylic Acid. It is made by Ziska Pharmaceuticals Ltd. It belongs to the Oral preparations group of medicines.

What is Orofresh OS used for?

Rhubarb Extract + Salicylic Acid oral solution is used to treat acute and chronic inflammation of the lining (mucosa) of the mouth, gums and throat. This includes aphthous ulcer, cold sore, gingivitis, periodontitis, dental hypersensitivity, dental plaque and denture irritation.

What are the side effects of Orofresh OS?

A short-lived burning feeling where the medicine is applied is very common with Rhubarb Extract + Salicylic Acid. Some people also notice temporary discoloration of the teeth or the lining of the mouth, which is commonly reported after using the oral solution.

Can I take Orofresh OS during pregnancy or while breastfeeding?

Pregnancy: There are not enough animal studies to say how Rhubarb Extract + Salicylic Acid affects pregnancy or the development of the embryo and foetus. The possible risk to humans is not known. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

What happens if I take too much Orofresh OS?

An overdose from applying Rhubarb Extract + Salicylic Acid to the skin is unlikely, though nobody knows how much salicylic acid and how many anthraquinone derivatives actually get absorbed into the body. If the medicine is swallowed and the overdose becomes systemic, it might cause abdominal cramping and diarrhea. In an emergency call 999 or go to the nearest hospital emergency department.

How should I store Orofresh OS?

Keep Rhubarb Extract + Salicylic Acid in a cool, dry place, away from light.

Do I need a prescription for Orofresh OS?

Orofresh OS is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 20 Aug 2026