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These brands contain the same active ingredient (Promethazine Theoclate). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Novomit is indicated for:
Pharmacology
Promethazine Theoclate works by stopping histamine from binding to its receptors in an area of the brain known as the vomiting centre. The vomiting centre is responsible for causing feelings of sickness and for the vomiting reflex. It is activated when it receives nerve messages from the vestibular apparatus in the middle ear.
The vestibular apparatus provides constant feedback to the brain about the position of our body. When something disturbs the vestibular apparatus, such as movements of the head when travelling by boat or car, nerve signals are sent from the vestibular apparatus to the vomiting centre. This can cause the symptoms of motion sickness, such as nausea, dizziness or spinning sensations (vertigo), and vomiting.
By blocking the histamine receptors in the vomiting centre, Promethazine Theoclate prevents disturbances in the middle ear from activating the vomiting centre.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Motion sickness
Adults: For prevention on long trips, take one 25 mg tablet each evening at bedtime, starting the day before you set out. Because the drug lasts a long time, a second dose within 24 hours is not often needed.
For prevention on short trips, take one 25 mg tablet one or two hours before you travel, or as soon as possible after that.
Treatment of motion sickness: take one 25mg tablet as soon as possible, repeat it the same evening, then take a third tablet the following evening.
Nausea and vomiting due to other causes
Adults: One 25mg tablet at night is often enough, but two or three tablets are sometimes needed. Some patients may instead need 25mg two or three times a day. It is not often necessary to take more than four of the 25mg Avomine tablets in 24 hours.
Children: For the indications above, children over 10 years of age may be given the lower adult doses described above. Children between 5 and 10 years may be given half the adult dose.
Elderly: No specific dosage recommendations are available.
Side Effects
Side-effects may occur in a small number of patients, including drowsiness, dizziness, restlessness, headaches, nightmares, tiredness and disorientation. Anticholinergic effects such as blurred vision, dry mouth and difficulty passing urine occur occasionally. Elderly patients are particularly prone to these anticholinergic effects and to confusion caused by promethazine. Other possible side-effects include loss of appetite, stomach irritation, palpitations, low blood pressure, irregular heartbeat, extrapyramidal effects, muscle spasms and tic-like movements of the head and face. Rarely, anaphylaxis, jaundice and blood disorders such as haemolytic anaemia may occur. Skin reactions triggered by sunlight have also been reported, so strong sunlight should be avoided while taking this medicine.
Cautions & Contraindications
Warnings & Precautions
Avomine tablets can make some people feel drowsy, dizzy, confused or disorientated, and this may reduce your ability to drive or operate machinery safely. Do not drive or operate machinery until you know how this medicine affects you and are sure it won't affect your performance. If your child is affected in this way, they should avoid potentially hazardous activities such as riding bikes. You should not leave your child unattended after giving them this medicine. Avoid drinking alcohol while taking Avomine, because this is likely to make the above effects more likely or worse. Avomine tablets may make your skin more sensitive to sunlight than usual, so you should avoid exposing your skin to direct sunlight or sunlamps until you know how your skin reacts. If you cannot avoid strong sunlight, use a sunscreen lotion or make sure your skin is protected with clothing. This medicine may interfere with some pregnancy tests, causing false negative or false positive results. If you are due to have any skin prick tests to diagnose allergies, you should stop taking Avomine at least 72 hours before the tests. This is because antihistamines can prevent or lessen the skin reactions that indicate an allergy, so they can make the test results unreliable.
Contraindications
Do not give Promethazine Teoclate Tablets to a child under 2 years old. Do not take this medicine if you have ever had an allergic reaction to promethazine, to any phenothiazine, or to any of its ingredients; if you have taken medicines for depression known as Monoamine Oxidase Inhibitors (MAOIs) within the last 14 days; or if you have CNS depression, in which a person seems sleepy or unconscious, including coma. Take special care with Promethazine Teoclate Tablets and tell your doctor or pharmacist if you suffer from glaucoma (increased pressure in the eye), epilepsy, heart problems, liver problems, kidney or bladder problems, a chest condition such as asthma or bronchitis, severe headaches with blurred vision, severe stomach pains with vomiting, dizziness, difficulty keeping your balance, ringing in the ears or other ear problems along with feeling sick, a bad cough, or Reye's Syndrome or symptoms of it, including persistent vomiting, tiredness, or sleepiness. Do not take Promethazine Teoclate Tablets for more than 7 days without contacting your doctor.
Pregnancy & Breastfeeding
Use in pregnancy: Studies in humans have not shown promethazine to be harmful in pregnancy, and animal studies have shown no hazard either. Even so, it should only be used in pregnancy if a physician judges it to be essential. Avomine tablets are not recommended in the two weeks before delivery, because of a risk of irritability and excitement in the newborn.
Use in breastfeeding: The available evidence suggests that only an insignificant amount passes into breast milk. Even so, there is a risk of irritability and excitement in the newborn. Patients taking Avomine for the first time and going about their normal activities should not drive or operate machinery for the first few days, until it is clear that they are not unusually sensitive to its effects on the central nervous system and are not experiencing disorientation, confusion, or dizziness.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Symptoms of severe overdosage with promethazine theoclate are variable. In children they show up as various combinations of excitation, ataxia, inco-ordination, athetosis and hallucinations. Adults, on the other hand, may become drowsy and lapse into coma. Convulsion can occur in both adults and children, and coma or excitement may come before it. Cardiorespiratory depression is uncommon.
If the patient is seen soon enough after ingestion, it should be possible to induce vomiting with ipecacuanha, even though promethazine has an anti-emetic effect. Gastric lavage may be used instead. Otherwise the treatment is supportive, with attention to keeping respiratory and circulatory status adequate. Convulsions should be treated with diazepam or another suitable anticonvulsant.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Don't use Promethazine Theoclate after the expiry date. Keep all medicines out of the reach of children. It should be dispensed only on the prescription of a registered physician.
Common questions about Novomit 25 mg
What is Novomit 25 mg Tablet?
Novomit 25 mg Tablet is a medicine that contains Promethazine Theoclate. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Anti-emetic drugs group of medicines.
What is Novomit used for?
Novomit is used for: Vertigo, Nausea and Vomiting.
What are the side effects of Novomit?
Side-effects may occur in a small number of patients, including drowsiness, dizziness, restlessness, headaches, nightmares, tiredness and disorientation. Anticholinergic effects such as blurred vision, dry mouth and difficulty passing urine occur occasionally.
Can I take Novomit during pregnancy or while breastfeeding?
Use in pregnancy: Studies in humans have not shown promethazine to be harmful in pregnancy, and animal studies have shown no hazard either. Even so, it should only be used in pregnancy if a physician judges it to be essential. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Novomit?
Symptoms of severe overdosage with promethazine theoclate are variable. In children they show up as various combinations of excitation, ataxia, inco-ordination, athetosis and hallucinations. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Novomit?
Don't use Promethazine Theoclate after the expiry date. Keep all medicines out of the reach of children.
Do I need a prescription for Novomit?
Novomit is a prescription (Rx) medicine. Take it as your doctor advises.