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Other brands with the same active ingredient
These brands contain the same active ingredient (Sumatriptan). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Pharmacology
Sumatriptan acts as an agonist at a vascular 5-hydroxytryptamine receptor subtype (probably belonging to the 5-HT family). It has only weak affinity for 5-HT, 5-HT, and 5-HT receptors, and shows no significant affinity (measured with standard radioligand binding assays) or pharmacological activity at 5-HT, 5-HT, or 5-HT receptor subtypes, nor at alpha-adrenergic, beta-adrenergic, dopamine, muscarinic, or benzodiazepine receptors. The vascular 5-HT receptor subtype activated by sumatriptan is found on cranial arteries in both dogs and primates, on the human basilar artery, and in the vasculature of human dura mater, where it mediates vasoconstriction. In humans, this action correlates with relief from migraine headache. Besides causing vasoconstriction, experimental data from animal studies show that sumatriptan also activates 5-HT receptors on the peripheral terminals of the trigeminal nerve that innervate cranial blood vessels. This action may also contribute to sumatriptan's antimigrainous effect in humans.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
In controlled clinical trials, single doses of 25 mg, 50 mg or 100 mg were effective for the acute treatment of migraine in adults. Evidence suggests that 50 mg and 100 mg doses may work better than 25 mg, but that 100 mg does not work better than 50 mg. Because people respond differently to Sumatriptan tablets, the dose should be chosen for each patient individually, weighing the possible benefit of a higher dose against the greater risk of side effects.
If the headache returns, or if the patient has only a partial response to the first dose, the dose may be repeated after 2 hours. The total daily dose should not exceed 200 mg. If a headache returns after initial treatment with Sumatriptan injection, additional single Sumatriptan tablets (up to 100 mg per day) may be given, with at least 2 hours between tablet doses. The safety of treating more than an average of 4 headaches in a 30-day period has not been established.
Use in children and adolescents: Sumatriptan is not recommended for patients under 18 years of age.
Dosage for other forms (1)
A single dose is 10 mg. The maximum dose in any 24-hour period is 30 mg. Doses should be separated by at least one hour, or as directed by the physician.
Side Effects
Common side effects of the nasal spray include an unusual or unpleasant taste in the mouth; pain, burning, numbness or tingling in the nose or throat; and a runny or blocked nose after use. Less commonly, people may experience anxiety, a burning sensation, discomfort in the nose and throat, a general feeling of being unwell or tired, and changes in vision.
Cautions & Contraindications
Warnings & Precautions
Myocardial ischemia, infarction and Prinzmetal's angina: patients with several cardiovascular risk factors should have a cardiac evaluation before use. Arrhythmias: stop Sumatrex if an arrhythmia develops. Chest, throat, neck or jaw pain, tightness, pressure or heaviness: these are generally not associated with myocardial ischemia, but patients at high risk should be evaluated for coronary artery disease. Cerebral hemorrhage, subarachnoid hemorrhage and stroke: stop Sumatrex if any of these occurs. Gastrointestinal ischemia and reactions, and peripheral vasospastic reactions: stop Sumatrex if these occur. Medication overuse headache: detoxification may be necessary. Serotonin syndrome: stop Sumatrex if it occurs. Increase in blood pressure: a hypertensive crisis can occur. Hypersensitivity reactions: angioedema and anaphylaxis can occur. Seizures: use with caution in patients with epilepsy or a lowered seizure threshold. Local irritation: burning and an abnormal taste can occur.
Contraindications
Sumatriptan must not be used by people with a history of coronary artery disease or coronary vasospasm. It is also not for those with Wolff-Parkinson-White syndrome or other cardiac accessory conduction pathway disorders, or a history of stroke, transient ischemic attack, or hemiplegic or basilar migraine. Peripheral vascular disease, ischemic bowel disease and uncontrolled hypertension rule it out too. Don't give it within 24 hours of another 5 HT1 agonist (for example, another triptan) or of an ergotamine containing medicine. It is also contraindicated with concurrent or recent use (in the past 2 weeks) of a monoamine oxidase A inhibitor. Hypersensitivity to sumatriptan is a contraindication as well, since angioedema and anaphylaxis have been seen. The last one is severe hepatic impairment.
Pregnancy & Breastfeeding
Pregnancy Category C: well-controlled studies in pregnant women are lacking. Sumatriptan does pass into breast milk after a subcutaneous dose, so a nursing mother can limit her infant's exposure by not breastfeeding for 12 hours after taking Sumatriptan Tablets.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
There is no specific data on what happens if someone takes too much of Suma 10 mg nasal spray.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Sumatriptan at a temperature between 20°C and 25°C. Don't keep it in the refrigerator or the freezer. Don't test it before you use it.
Drug Interactions
Common questions about Nomigra 50 mg
What is Nomigra 50 mg Tablet?
Nomigra 50 mg Tablet is a medicine that contains Sumatriptan. It is made by Ambee Pharmaceuticals Ltd. It belongs to the 5-HT Agonists group of medicines.
What is Nomigra used for?
Nomigra is used for: Migraine, Headache.
What are the side effects of Nomigra?
Common side effects of the nasal spray include an unusual or unpleasant taste in the mouth; pain, burning, numbness or tingling in the nose or throat; and a runny or blocked nose after use. Less commonly, people may experience anxiety, a burning sensation, discomfort in the nose and throat, a general feeling of being unwell or tired, and changes in vision.
Can I take Nomigra during pregnancy or while breastfeeding?
Pregnancy Category C: well-controlled studies in pregnant women are lacking. Sumatriptan does pass into breast milk after a subcutaneous dose, so a nursing mother can limit her infant's exposure by not breastfeeding for 12 hours after taking Sumatriptan Tablets. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Nomigra?
There is no specific data on what happens if someone takes too much of Suma 10 mg nasal spray. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Nomigra?
Keep Sumatriptan at a temperature between 20°C and 25°C. Don't keep it in the refrigerator or the freezer.
Can I take other medicines with Nomigra?
Some medicines can interact with Sumatriptan, for example: Noradrenaline. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Nomigra?
Nomigra is a prescription (Rx) medicine. Take it as your doctor advises.