More from Nikethamide
Other strengths and forms by Jayson Pharmaceuticals Ltd.
Indications & Uses
Nikethamide is indicated for:
Pharmacology
Nikethamide, also called nicotinic acid diethylamide, is a central and respiratory stimulant. It acts directly on the CNS to make breathing faster and deeper. It does not have any immediate effect on the cardiovascular system. The liver breaks it down extensively, and both the metabolites and a small amount of unchanged drug are passed out in the urine.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults may be given 2 to 10 mL of the usual 25% solution as a slow intravenous injection, repeated every 20 to 30 minutes if needed. Infants and children are especially prone to nikethamide's toxic effects.
Side Effects
Nikethamide can cause dyspnoea and other breathing problems, such as coughing and bronchospasm. Its other CNS side effects include convulsion, headache and dizziness. On the cardiovascular side, it can bring about iteration of blood pressure and cardiac arrhythmia. An overdose of Nikethamide may cause nausea, vomiting and diarrhoea.
Cautions & Contraindications
Warnings & Precautions
Nikethamide should not be used in less severe degrees of hypertension, or in people with impaired cardiac reserve or hepatic dysfunction.
Contraindications
Contraindicated in porphyria; epilepsy or other convulsive disorders; cerebral oedema; airways obstruction; cerebrovascular accident; severe hypertension; and ischemic heart disease.
Pregnancy & Breastfeeding
There are not enough well-controlled studies on the use of nikethamide in pregnant or breastfeeding women.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Nikethamide in a dry place below 25°C, and away from light.
Drug Interactions
Common questions about Nikethamide 500 mg
What is Nikethamide 500 mg Injection?
Nikethamide 500 mg Injection is a medicine that contains Nikethamide. It is made by Jayson Pharmaceuticals Ltd. It belongs to the Respiratory stimulants: analeptics group of medicines.
What is Nikethamide used for?
Nikethamide is used for: Depression.
What are the side effects of Nikethamide?
Nikethamide can cause dyspnoea and other breathing problems, such as coughing and bronchospasm. Its other CNS side effects include convulsion, headache and dizziness.
Can I take Nikethamide during pregnancy or while breastfeeding?
There are not enough well-controlled studies on the use of nikethamide in pregnant or breastfeeding women. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Nikethamide?
Keep Nikethamide in a dry place below 25°C, and away from light.
Can I take other medicines with Nikethamide?
Some medicines can interact with Nikethamide, for example: Bupropion Hydrochloride. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Nikethamide?
Nikethamide is a prescription (Rx) medicine. Take it as your doctor advises.