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Other brands with the same active ingredient
These brands contain the same active ingredient (Zolpidem Tartrate). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Nidraj is indicated for:
Pharmacology
Zolpidem is a positive modulator at the GABA A receptor and is thought to produce its effects in the short-term treatment of transient insomnia by binding to the benzodiazepine site on GABA A receptors that contain the α1 subunit, which increases how often the chloride channel opens and thereby inhibits neuronal excitation. Zolpidem binds to GABA A receptors with greater affinity for the α1 subunit than for receptors containing the α2 or α3 subunit, and it shows no appreciable binding affinity for GABA A receptors containing the α5 subunit. This binding profile may account for the relative absence of muscle-relaxant effects seen in animal studies. Zolpidem also shows no appreciable binding affinity for dopaminergic D2, serotonergic 5HT2, adrenergic, histaminergic, or muscarinic receptors.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Zolpidem Tartrate Capsules come only in a 7.5 mg strength. If a patient needs 5 mg or 10 mg, use another zolpidem tartrate immediate-release product instead. Avoid using Zolpidem Tartrate Capsules in geriatric patients.
The recommended dosage is the lowest effective dose of zolpidem tartrate.
Females: The recommended starting dosage of zolpidem tartrate immediate-release is 5 mg once nightly. Use another zolpidem tartrate immediate-release product to start the dose in females.
Males: The recommended starting dosage of zolpidem tartrate immediate-release is either 5 mg of the immediate-release product, 7.5 mg as Zolpidem Tartrate Capsules, or 10 mg of the immediate-release product, once nightly. For the 5 mg and 10 mg doses, use another zolpidem tartrate immediate-release product.
In both males and females: If a 5 mg nightly dose of another zolpidem tartrate immediate-release product doesn't work, the dose may be increased to 7.5 mg once nightly as Zolpidem Tartrate Capsules, or to 10 mg once nightly of another zolpidem tartrate immediate-release product. The maximum recommended dosage of zolpidem tartrate immediate-release is 10 mg once nightly. Zolpidem Tartrate Capsules are for short-term use only.
Administer Zolpidem Tartrate Capsules orally, once per night, immediately before bedtime, with at least 7 to 8 hours left before the planned time of awakening.
Don't take Zolpidem Tartrate Capsules with a meal or straight after one. Swallow the capsule whole. Do not open, crush or chew it.
Lower doses of CNS depressants may be necessary when they are taken together with Zolpidem Tartrate Capsules.
Side Effects
Most people notice headache, drowsiness, dizziness, or diarrhea as the most common side effects. More serious reactions can also occur, and these are covered in detail elsewhere in this labeling: complex sleep behaviors, CNS-depressant effects with next-day impairment, severe anaphylactic and anaphylactoid reactions, abnormal thinking and behavior changes, and withdrawal effects.
Cautions & Contraindications
Warnings & Precautions
CNS-Depressant Effects: This medicine can impair alertness and motor coordination, including a risk of impairment the morning after use. This risk grows with higher doses and when combined with other CNS depressants or alcohol. Patients should be cautioned against driving or performing other activities requiring mental alertness the morning after taking it, and should be instructed on the correct way to use it. Need to Evaluate for Comorbid Diagnoses: If insomnia continues after 7 to 10 days of use, the patient should be reevaluated, since persistent insomnia may point to an underlying comorbid condition. Severe Anaphylactic/Anaphylactoid Reactions: Angioedema and anaphylactic or anaphylactoid reactions have been reported. The medicine should not be given again to a patient who has experienced such a reaction. Abnormal Thinking and Behavioral Changes: Abnormal thinking and behavioral changes, including reduced inhibition, bizarre behavior, agitation, and depersonalization, have been reported. Any new behavioral changes should be evaluated right away. Depression: Depression or suicidal thinking may worsen. The smallest number of capsules practical should be prescribed to reduce the chance of an intentional overdose. Respiratory Depression: The risk of respiratory depression should be weighed before prescribing this medicine to patients with compromised respiratory function. Precipitation of Hepatic Encephalopathy: Nitrest should be avoided in patients with severe liver impairment. Withdrawal Effects: Withdrawal symptoms may occur if the dose is reduced quickly or the medicine is stopped suddenly.
Contraindications
Zolpidem Tartrate Capsules should not be used by patients who are known to be hypersensitive to zolpidem, or who have experienced complex sleep behaviors after taking it. Reactions observed in such cases include anaphylaxis and angioedema.
Pregnancy & Breastfeeding
A pregnancy exposure registry tracks outcomes in women who take psychiatric medications, including zolpidem tartrate, during pregnancy. Limited published data show that zolpidem tartrate can pass into human breast milk, and some infants who were breastfed while their mothers used it have shown excess sedation as a result.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Children: Safety and effectiveness of Zolpidem Tartrate have not been established. In a study of pediatric patients with Attention-Deficit/Hyperactivity Disorder, hallucinations were seen often (incidence rate 7%), along with other psychiatric and/or nervous system adverse reactions.
Elderly patients: Zolpidem Tartrate Capsules are not indicated in geriatric patients. The 7.5 mg capsule should be avoided in this age group, because the dose can't be adjusted as needed with the strength that is available.
Storage
Store Zolpidem Tartrate below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Nidraj 10 mg
What is Nidraj 10 mg Tablet?
Nidraj 10 mg Tablet is a medicine that contains Zolpidem Tartrate. It is made by Alco Pharma Limited. It belongs to the Miscellaneous sedatives & hypnotics group of medicines.
What is Nidraj used for?
Nidraj is used for: Insomnia.
What are the side effects of Nidraj?
Most people notice headache, drowsiness, dizziness, or diarrhea as the most common side effects. More serious reactions can also occur, and these are covered in detail elsewhere in this labeling: complex sleep behaviors, CNS-depressant effects with next-day impairment, severe anaphylactic and anaphylactoid reactions, abnormal thinking and behavior changes, and withdrawal effects.
Can I take Nidraj during pregnancy or while breastfeeding?
A pregnancy exposure registry tracks outcomes in women who take psychiatric medications, including zolpidem tartrate, during pregnancy. Limited published data show that zolpidem tartrate can pass into human breast milk, and some infants who were breastfed while their mothers used it have shown excess sedation as a result. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Nidraj?
Store Zolpidem Tartrate below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Nidraj?
Some medicines can interact with Zolpidem Tartrate, for example: Dextromethorphan + Phenylephrine + Triprolidine, Chlorpromazine Hydrochloride, Imipramine Hydrochloride. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Nidraj?
Nidraj is a prescription (Rx) medicine. Take it as your doctor advises.