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Same active ingredient — pay up to 38% less
These brands contain the same active ingredient (Telmisartan). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Mitosan
Other strengths and forms by Nevian Lifescience PLC
Indications & Uses
Mitosan is indicated for:
Pharmacology
Telmisartan belongs to a class of medicines called angiotensin-II receptor blockers, and it works by interrupting one of the body's key blood pressure control systems. Normally, an enzyme called angiotensin-converting enzyme (ACE) converts angiotensin-I into angiotensin-II, a hormone that is the main driver of the renin-angiotensin system. Angiotensin-II raises blood pressure in several ways: it narrows blood vessels, triggers the adrenal glands to produce and release aldosterone, stimulates the heart, and causes the kidneys to hold on to more sodium.
Telmisartan does not stop angiotensin-II from being made. Instead, it works further downstream by selectively blocking the AT1 receptor, the site where angiotensin-II would normally attach to produce its effects on tissues such as vascular smooth muscle and the adrenal gland. By preventing angiotensin-II from binding to this receptor, telmisartan blocks its ability to constrict blood vessels and stimulate aldosterone release, regardless of how the angiotensin-II was produced in the first place.
Telmisartan is highly selective for the AT1 receptor, binding to it more than 3,000 times as strongly as to the related AT2 receptor. Unlike ACE inhibitors, telmisartan does not block the enzyme kininase-II (the same enzyme as ACE), so it does not interfere with the breakdown of bradykinin, a substance involved in other bodily responses. It also does not act on other hormone receptors or ion channels known to play a role in regulating the cardiovascular system.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage should be tailored to each patient. The usual starting dose of Telmisartan tablets is 40 mg once daily. Blood pressure response is dose related across the range of 20 to 80 mg. Most of the antihypertensive effect shows up within 2 weeks, and the maximal reduction is generally reached after 4 weeks. If additional blood pressure lowering is needed beyond what 80 mg of Telmisartan provides, a switch to combination therapy may be considered. No initial dosage adjustment is needed for elderly patients or for patients with renal impairment, including those on hemodialysis. Patients on dialysis may develop orthostatic hypotension, so their blood pressure should be monitored closely. Telmisartan tablets may be given together with other antihypertensive agents, and may be taken with or without food. Starting Telmisartan therapy is not recommended in patients aged 75 years or older or in those with hepatic impairment.
Pediatric use: the safety and effectiveness of Telmisartan in pediatric patients have not been established.
Geriatric use: no overall differences in effectiveness and safety were seen in these patients compared with younger patients.
Hepatic impairment: monitor carefully and increase the dose slowly in patients with biliary obstructive disorders or hepatic insufficiency.
Side Effects
In hypertensive patients, the most commonly reported side effects of Trusert tablets include sinus pain and congestion (sinusitis), back pain, and diarrhea, among others. In patients using it for CV (cardiovascular) risk reduction, the most commonly reported side effects of Trusert tablets include intermittent claudication and skin ulcer.
Cautions & Contraindications
Warnings & Precautions
Avoid use during pregnancy or breastfeeding due to risk to the baby. May cause low blood pressure. Monitor closely in patients with liver or kidney problems. Do not use together with an ACE inhibitor and another angiotensin receptor blocker.
Contraindications
Hypersensitivity to telmisartan or any other ingredient in this product.
Pregnancy & Breastfeeding
Telmisartan should not be used during pregnancy. It falls in Pregnancy Category C in the first trimester and Category D in the second and third trimesters. If you are breastfeeding, your doctor will need to decide whether to stop breastfeeding or stop the medicine, weighing how important telmisartan is for your own health.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
If someone takes too much Telmisartan, the most likely effects are low blood pressure (hypotension), dizziness and a fast heartbeat (tachycardia). A slow heartbeat (bradycardia), a rise in serum creatinine and acute renal failure could also occur, from parasympathetic (vagal) stimulation.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Telmisartan below 30°C. Keep it away from light and high humidity, and out of the reach of children.
Drug Interactions
Common questions about Mitosan 40 mg
What is Mitosan 40 mg Tablet?
Mitosan 40 mg Tablet is a medicine that contains Telmisartan. It is made by Nevian Lifescience PLC. It belongs to the Angiotensin-ll receptor blocker group of medicines.
What is Mitosan used for?
Mitosan is used for: Hypertension, Stroke, Type 2 Diabetes Mellitus, Diabetes Mellitus.
What are the side effects of Mitosan?
In hypertensive patients, the most commonly reported side effects of Trusert tablets include sinus pain and congestion (sinusitis), back pain, and diarrhea, among others. In patients using it for CV (cardiovascular) risk reduction, the most commonly reported side effects of Trusert tablets include intermittent claudication and skin ulcer.
Can I take Mitosan during pregnancy or while breastfeeding?
Telmisartan should not be used during pregnancy. It falls in Pregnancy Category C in the first trimester and Category D in the second and third trimesters. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Mitosan?
If someone takes too much Telmisartan, the most likely effects are low blood pressure (hypotension), dizziness and a fast heartbeat (tachycardia). A slow heartbeat (bradycardia), a rise in serum creatinine and acute renal failure could also occur, from parasympathetic (vagal) stimulation. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Mitosan?
Store Telmisartan below 30°C. Keep it away from light and high humidity, and out of the reach of children.
Can I take other medicines with Mitosan?
Some medicines can interact with Telmisartan, for example: Aliskiren, Amlodipine Besilate + Telmisartan. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Telmicard by Drug International Unani Ltd. has the same ingredient and strength for ৳8.00 per unit, compared with ৳13.00 for Mitosan. Ask your doctor or pharmacist before switching.
Do I need a prescription for Mitosan?
Mitosan is a prescription (Rx) medicine. Take it as your doctor advises.