Pricing
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Micagin is indicated for:
Pharmacology
Micafungin is a sterile, freeze-dried (lyophilized) product that is given as an intravenous (IV) infusion, and it contains Micafungin Sodium. The active ingredient is a semisynthetic lipopeptide of the echinocandin type. It works by blocking the synthesis of 1,3-β-D-glucan, which is an integral part of the fungal cell wall. Mammalian cells don't have this component.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
In children aged 4 months or older and in elderly patients, the Micafungin dose for treatment of invasive candidiasis is 100 mg/day when body weight is more than 40 kg, and 2 mg/kg/day when it is 40 kg or less. For treatment of oesophageal candidiasis (only for patients 16 years of age or older), the dose is 150 mg/day above 40 kg and 3 mg/kg/day at 40 kg or less. Prophylaxis of Candida infection uses 50 mg/day for more than 40 kg, and 1 mg/kg/day for 40 kg or less.
Children under 4 months of age, including neonates, get 4 to 10 mg/kg/day for treatment of invasive candidiasis and 2 mg/kg/day for prophylaxis of Candida infection. No loading dose is required.
Side Effects
The most common side effects of Micafungin Sodium are diarrhea, nausea, vomiting, pyrexia (fever), hypokalemia, thrombocytopenia and headache. Some people also get histamine-mediated symptoms, such as rash, pruritus, facial swelling and vasodilation.
Cautions & Contraindications
Warnings & Precautions
If anaphylaxis or an anaphylactoid reaction occurs, stop Micafungin Sodium and give appropriate treatment. Isolated cases of acute intravascular hemolysis, hemolytic anemia and hemoglobinuria have been reported. Patients who develop these problems need close monitoring, and the risk and benefit of continuing Micafungin Sodium therapy should be weighed. Close monitoring is also needed for patients whose liver function tests turn abnormal (such as hepatic dysfunction, hepatitis and hepatic failure), and again the risk and benefit of continuing Micafungin Sodium therapy should be evaluated. Patients with renal dysfunction and acute renal failure should also be monitored closely.
Contraindications
Micafungin Sodium must not be given to patients who are known to be hypersensitive to micafungin or to any other component of the preparation.
Pregnancy & Breastfeeding
No adequate and well-controlled studies of Micafungin have been done in pregnant women. So Micafungin should be used in pregnancy only if the possible benefit justifies the possible risk to the fetus.
It is not known whether Micafungin passes into human milk. Take care when Micafungin Sodium is given to a nursing mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Micafungin Sodium is highly protein bound, so it can't be removed by dialysis. No case of Micafungin Sodium overdose has been reported. In clinical trials, adult patients were given repeated daily doses of up to 8 mg/kg (a maximum total dose of 896 mg), and no dose-limiting toxicity was reported.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Before reconstitution, store Micafungin Sodium at a temperature not above 30°C. Keep it away from light and out of the reach of children.
After reconstitution, don't store the solution above 30°C. The diluted infusion should be protected from light, and it may be stored for up to 24 hours at room temperature.
Drug Interactions
Common questions about Micagin 50 mg
What is Micagin 50 mg IV Infusion?
Micagin 50 mg IV Infusion is a medicine that contains Micafungin Sodium. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Other Antifungal preparations group of medicines.
What is Micagin used for?
Micagin is used for: Fungal Infection.
What are the side effects of Micagin?
The most common side effects of Micafungin Sodium are diarrhea, nausea, vomiting, pyrexia (fever), hypokalemia, thrombocytopenia and headache. Some people also get histamine-mediated symptoms, such as rash, pruritus, facial swelling and vasodilation.
Can I take Micagin during pregnancy or while breastfeeding?
No adequate and well-controlled studies of Micafungin have been done in pregnant women. So Micafungin should be used in pregnancy only if the possible benefit justifies the possible risk to the fetus. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Micagin?
Micafungin Sodium is highly protein bound, so it can't be removed by dialysis. No case of Micafungin Sodium overdose has been reported. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Micagin?
Before reconstitution, store Micafungin Sodium at a temperature not above 30°C. Keep it away from light and out of the reach of children.
Can I take other medicines with Micagin?
Some medicines can interact with Micafungin Sodium, for example: Nifedipine, Itraconazole. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Micagin?
Micagin is a prescription (Rx) medicine. Take it as your doctor advises.