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Other brands with the same active ingredient
These brands contain the same active ingredient (Donepezil Hydrochloride). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Memorin is indicated for:
Pharmacology
Donepezil Hydrochloride works on the brain by blocking an enzyme called acetylcholinesterase, whose normal job is to break down a chemical messenger called acetylcholine. The medicine attaches to this enzyme and switches it off for a while, so acetylcholine is not broken down as quickly. This allows acetylcholine levels to build up at the nerve junctions in the brain, helping nerve cells communicate more effectively.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
5 mg once daily by mouth at bedtime. This 5 mg/day dose should be continued for at least one month, allowing early clinical response to be assessed and steady-state concentrations of donepezil hydrochloride to be reached. After this one-month assessment at 5 mg/day, the dose can be increased to 10 mg/day, still taken once a day. Because food does not affect how much or how quickly donepezil is absorbed, it may be taken with or without food.
Side Effects
Generally well tolerated, though some patients may notice nausea, vomiting, or diarrhoea. These effects tend to be mild and short-lived, usually settling on their own as treatment continues, without needing a dose change. Less commonly, patients may experience insomnia, fatigue, loss of appetite, muscle cramps, or generalized seizures.
Cautions & Contraindications
Warnings & Precautions
Caution is advised in patients with sick sinus syndrome or other conduction disorders affecting the heart's upper chambers, as well as in those prone to peptic ulcers or living with asthma or other obstructive airway disease. Care should also be taken when anaesthesia is being planned.
Contraindications
Donepezil should not be used by anyone who is hypersensitive to donepezil hydrochloride or to piperidine derivatives.
Pregnancy & Breastfeeding
Pregnancy: There isn't enough well-controlled research on Donepezil's use in pregnant women. It should only be used during pregnancy if the expected benefit to the mother outweighs any possible risk to the unborn baby.
Breastfeeding: It is not known whether Donepezil Hydrochloride passes into human breast milk. It is not recommended for use in breastfeeding mothers.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Renal and hepatic impairment: Patients with kidney problems, or with mild to moderate liver impairment, can follow a similar dose schedule, because these conditions don't affect the clearance of Donepezil Hydrochloride.
Use in children: There are no adequate and well controlled trials on the safety and efficacy of Donepezil Hydrochloride in any illness that occurs in children. It is not recommended for use in children.
Overdose
An overdose of donepezil can cause nausea, vomiting and increased salivation. A very high dose may lead to a cholinergic crisis. This shows up as severe nausea, vomiting, salivation, slow heart rate (bradycardia), low blood pressure (hypotension), increasing muscle weakness, respiratory depression, collapse and convulsion.
As with any overdose, general supportive measures should be used. If a cholinergic crisis develops, the patient must be admitted to hospital.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Donepezil Hydrochloride below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Memorin 5 mg
What is Memorin 5 mg Tablet?
Memorin 5 mg Tablet is a medicine that contains Donepezil Hydrochloride. It is made by Beximco Pharmaceuticals Ltd. It belongs to the Drugs for Dementia group of medicines.
What is Memorin used for?
Memorin is used for: Alzheimer's Disease.
What are the side effects of Memorin?
Generally well tolerated, though some patients may notice nausea, vomiting, or diarrhoea. These effects tend to be mild and short-lived, usually settling on their own as treatment continues, without needing a dose change.
Can I take Memorin during pregnancy or while breastfeeding?
Pregnancy: There isn't enough well-controlled research on Donepezil's use in pregnant women. It should only be used during pregnancy if the expected benefit to the mother outweighs any possible risk to the unborn baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Memorin?
An overdose of donepezil can cause nausea, vomiting and increased salivation. A very high dose may lead to a cholinergic crisis. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Memorin?
Store Donepezil Hydrochloride below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Memorin?
Some medicines can interact with Donepezil Hydrochloride, for example: Atropine Sulphate, Carbamazepine, Dexamethasone, Cimetidine, Ketoconazole, Phenytoin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Memorin?
Memorin is a prescription (Rx) medicine. Take it as your doctor advises.