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Same active ingredient — pay up to 28% less
These brands contain the same active ingredient (Mizolastine). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Mastel is indicated for:
Pharmacology
Mizolastine is a non-sedating antihistamine that works by blocking histamine H1-receptors on effector cells in the GI tract, blood vessels, and respiratory tract. It also has mast-cell-stabilising properties.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and children over 12 years old usually take one 10 mg tablet a day. It is not recommended for children under 12 years old.
Side Effects
Rhinor MR is generally well tolerated when taken at the recommended dose. The side effects most often seen include dry mouth, diarrhoea, abdominal pain, nausea, drowsiness, headache, dizziness, elevated liver enzymes, low blood pressure, a fast heartbeat and palpitations. Bronchospasm and worsening of asthma have also been reported; however, since asthma is common among patients taking this medicine, it is not clear whether the medicine itself was actually responsible.
Cautions & Contraindications
Warnings & Precautions
Patients should be told that a small number of people may feel sedated while taking this medicine. Because of this, it's best to check how you personally respond before you drive or carry out any tasks that need concentration or coordination.
Contraindications
Mizolastine should not be used by patients with clinically significant heart disease, a history of symptomatic arrhythmias, known or suspected prolongation of the QT interval, electrolyte disturbances (especially low blood potassium), or clinically significant slow heart rate. It should also be avoided in patients taking other medicines that reduce its breakdown in the body, in those with significantly impaired liver function, and in anyone hypersensitive to the drug.
Pregnancy & Breastfeeding
The safety of Mizolastine for use in human pregnancy has not been established. Evaluation of experimental animal studies does not indicate direct or indirect harmful effects with respect to the development of the embryo or foetus, the course of gestation, or peri- and post-natal development. Even so, Mizolastine should be avoided during pregnancy, particularly in the 1st trimester. Mizolastine is also excreted into breast milk, so it is not recommended during breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
If someone takes too much mizolastine, the person should be watched for symptoms and have their heart monitored for at least 24 hours. This monitoring should include the QT interval and the cardiac rhythm. Standard measures should also be used to remove any drug that hasn't yet been absorbed.
Haemodialysis is not likely to help. Studies in patients with renal insufficiency suggest it does not increase clearance of the drug.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Mizolastine in a cool, dry place and protect it from light. Make sure it is kept out of the reach of children.
Drug Interactions
Common questions about Mastel 10 mg
What is Mastel 10 mg Tablet (Modified Release)?
Mastel 10 mg Tablet (Modified Release) is a medicine that contains Mizolastine. It is made by Advanced Chemical Industries PLC. It belongs to the Non-sedating antihistamines group of medicines.
What is Mastel used for?
Mastel is used for: Allergic Rhinitis, Fever, Urticaria.
What are the side effects of Mastel?
Rhinor MR is generally well tolerated when taken at the recommended dose. The side effects most often seen include dry mouth, diarrhoea, abdominal pain, nausea, drowsiness, headache, dizziness, elevated liver enzymes, low blood pressure, a fast heartbeat and palpitations.
Can I take Mastel during pregnancy or while breastfeeding?
The safety of Mizolastine for use in human pregnancy has not been established. Evaluation of experimental animal studies does not indicate direct or indirect harmful effects with respect to the development of the embryo or foetus, the course of gestation, or peri- and post-natal development. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Mastel?
If someone takes too much mizolastine, the person should be watched for symptoms and have their heart monitored for at least 24 hours. This monitoring should include the QT interval and the cardiac rhythm. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Mastel?
Keep Mizolastine in a cool, dry place and protect it from light. Make sure it is kept out of the reach of children.
Can I take other medicines with Mastel?
Some medicines can interact with Mizolastine, for example: Erythromycin, Ketoconazole, Cyclosporine, Amiodarone Hydrochloride, Flecainide Acetate. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Rhinor MR by Opsonin Pharma Limited has the same ingredient and strength for ৳5.03 per unit, compared with ৳7.00 for Mastel. Ask your doctor or pharmacist before switching.
Do I need a prescription for Mastel?
Mastel is a prescription (Rx) medicine. Take it as your doctor advises.