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2.5 gm/5 ml

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৳90.30 per pack

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M

Magsum

Rx

2.5 gm/5 ml • IM/IV Injection

Magnesium Sulfate • Renata PLC

Therapeutic class: Specific mineral preparations

🌐 বাংলায় দেখুন

From ৳90.30 1 x 5

Available as: 2.5 gm/5 ml · 1 x 5

Indications & Uses

Magnesium Sulfate injection is mainly used to treat hypomagnesaemia and other magnesium deficiency states. It is also used for irregular heart beats, and sometimes it may be given as a laxative. Eclamag injection is indicated for the same uses, namely hypomagnesaemia, magnesium deficiency states, irregular heart beats and, at times, as a laxative. Magnesium Sulfate has anticonvulsant properties when given parenterally. So it may be used to prevent or control seizures linked with acute uremia, hypothyroidism and eclampsia. It is also used in bronchial asthma and cardiovascular disorder.

Pharmacology

Magnesium is the second most plentiful cation in the fluid inside cells. Many enzyme systems need it to work, and it has an important part in the transmission of nerve signals and in how easily muscles are excited. When the body is short of magnesium, a number of structural and functional disturbances follow.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Adult dose, intramuscular: for severe hypomagnesemia, Magnesium Sulfate is given as 1 to 5 g (2 to 10 mL of 50% solution) daily in divided doses. The dose is repeated daily until serum levels have returned to normal. If the deficiency is not severe, 1 g (2 ml of 50% solution) can be given once or twice daily. Serum magnesium levels should guide how long the dosing continues.

Intravenous: 1 to 4 g of magnesium sulfate injection may be given in a 10% to 20% solution, but only with great caution. The rate should not go above 1.5 mL of 10% solution or equivalent per minute until relaxation is obtained. The usual dose range is 1 to 40 g daily.

Electrolyte replenisher: 1 to 2 g in 50% solution is given intramuscularly four times a day until serum magnesium is within normal limits.

Usual pediatric dose, intramuscular: 20 to 40 mg per kg of body weight in a 20% solution, repeated as necessary.

For eclampsia: the first dose is 1 to 2 g in 25% or 50% solution, given intramuscularly. After that, 1 g is given every 30 minutes until relief is obtained. Blood pressure should be monitored after each injection.

Use in children and adolescents: Magnesium Sulfate seems to be beneficial as adjuvant therapy in the treatment of moderate to severe asthma in children.

Side Effects

Giving too much magnesium sulfate can lead to hypermagnesaemia. The symptoms may include nausea, vomiting, flushing of the skin, thirst, drowsiness, confusion and muscle weakness. Low blood pressure can also occur, because the blood vessels in the limbs widen (peripheral vasodilatation), and other similar symptoms may appear too. Rare side effects are diarrhea, or skin irritation after soaking.

Cautions & Contraindications

Warnings & Precautions

Be careful when giving Magnesium Sulfate to patients with impaired renal function, or to those who are taking digitalis glycosides. When magnesium salts are given by injection (parenteral route), they may strengthen the effect of neuromuscular blocking agents and of central nervous system depressants. Keep a check on the patient's blood pressure, respiratory rate and urinary output. Also watch for signs of overdose, such as loss of the patellar reflex, weakness, nausea, a feeling of warmth, flushing of the skin, drowsiness, double vision and slurred speech.

Contraindications

Magnesium Sulfate should not be used if a person has heart block, which is a defect in the heart's electrical pathways that lowers how well the heart works. It is also contraindicated in severe damage to the muscular wall of the heart (the myocardium) and in significantly decreased kidney function.

Pregnancy & Breastfeeding

Magnesium Sulfate crosses the placenta, so care is needed when it is given to a pregnant woman, as with any other drug. It is not known whether Magnesium Sulfate passes into human milk. As with many other drugs, a nursing mother should also be given it with caution.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Overdose

Too much magnesium in the blood (hypermagnesemia) causes respiratory depression and loss of deep tendon reflexes, both due to neuromuscular blockade. Other symptoms are nausea, vomiting, flushing, thirst, hypotension, drowsiness, confusion, slurred speech, double vision, bradycardia and muscle weakness.

⚠️ In an emergency call 999 or go to the nearest hospital emergency department.

Storage

Store in a cool, dry place, away from light and out of children's reach.

Drug Interactions

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Moderate Nifedipine

Common questions about Magsum 2.5 gm/5 ml

What is Magsum 2.5 gm/5 ml IM/IV Injection?

Magsum 2.5 gm/5 ml IM/IV Injection is a medicine that contains Magnesium Sulfate. It is made by Renata PLC. It belongs to the Specific mineral preparations group of medicines.

What is Magsum used for?

Magnesium Sulfate injection is mainly used to treat hypomagnesaemia and other magnesium deficiency states. It is also used for irregular heart beats, and sometimes it may be given as a laxative.

What are the side effects of Magsum?

Giving too much magnesium sulfate can lead to hypermagnesaemia. The symptoms may include nausea, vomiting, flushing of the skin, thirst, drowsiness, confusion and muscle weakness.

Can I take Magsum during pregnancy or while breastfeeding?

Magnesium Sulfate crosses the placenta, so care is needed when it is given to a pregnant woman, as with any other drug. It is not known whether Magnesium Sulfate passes into human milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

What happens if I take too much Magsum?

Too much magnesium in the blood (hypermagnesemia) causes respiratory depression and loss of deep tendon reflexes, both due to neuromuscular blockade. Other symptoms are nausea, vomiting, flushing, thirst, hypotension, drowsiness, confusion, slurred speech, double vision, bradycardia and muscle weakness. In an emergency call 999 or go to the nearest hospital emergency department.

How should I store Magsum?