Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago
Available as: 740 mg

Indications & Uses

Abametapir is a pediculicide, a medicine applied to the skin (topical) to treat head lice infestation in patients 6 months of age and older. It should be used as part of a complete lice management program, and the steps are these. Wash (with hot water) or dry-clean all recently worn clothing, hats, used bedding and towels. Wash personal care items such as combs, brushes and hair clips in hot water. Then use a fine-tooth comb or special nit comb to remove dead lice and nits.

Pharmacology

Abametapir (5, 5'-dimethyl 2, 2-bipyridinyl) is a metalloproteinase inhibitor. Metalloproteinases take part in physiological processes that are critical to egg development and to the survival of lice.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

LYBY is for use on the hair and scalp only. Don't take it by mouth, and don't use it in the eyes or in the vagina. Shake the bottle well before use.

Apply LYBY to dry hair. Use enough to coat the hair and scalp thoroughly, up to the full content of one bottle. Keep it away from the eyes. Massage it into the scalp and through all the hair, leave it on for 10 minutes, and then rinse off with warm water.

One application is a full course of treatment with LYBY. Throw away any product that is left over, and don't flush it down the sink or toilet.

Side Effects

The most common side effects of Abametapir are redness of the skin or scalp, rash, a burning feeling on the skin, skin irritation, vomiting, eye irritation, an itchy scalp, and changes in hair color.

Cautions & Contraindications

Warnings & Precautions

Risk of neonatal benzyl alcohol toxicity Abametapir contains benzyl alcohol, and exposure to benzyl alcohol through the body has been linked with serious adverse reactions and death in neonates and low birth-weight infants. Safety and effectiveness have not been established in children below 6 months of age. Abametapir is not recommended for children under 6 months because they may absorb more of it into the body. Risk of benzyl alcohol toxicity from accidental ingestion Abametapir should be given only under the direct supervision of an adult.

Pregnancy & Breastfeeding

Use in pregnancy and lactation: not established.

Use in children and adolescents: the safety of Abametapir has not been established in children below 6 months of age.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Overdose

If someone swallows Abametapir by accident, they should get medical advice straight away. Tell them to call their local poison control centre as well.

⚠️ In an emergency call 999 or go to the nearest hospital emergency department.

Storage

Keep Abametapir at 2° to 8° C, in a place that stays free from frost. Keep it away from light, and keep it out of the reach of children.

Common questions about Lyby Lotion 740 mg

What is Lyby Lotion 740 mg Lotion?

Lyby Lotion 740 mg Lotion is a medicine that contains Abametapir. It is made by Nuvista Pharma PLC.

What is Lyby Lotion used for?

Abametapir is a pediculicide, a medicine applied to the skin (topical) to treat head lice infestation in patients 6 months of age and older. It should be used as part of a complete lice management program, and the steps are these.

What are the side effects of Lyby Lotion?

The most common side effects of Abametapir are redness of the skin or scalp, rash, a burning feeling on the skin, skin irritation, vomiting, eye irritation, an itchy scalp, and changes in hair color.

Can I take Lyby Lotion during pregnancy or while breastfeeding?

Use in pregnancy and lactation: not established. Use in children and adolescents: the safety of Abametapir has not been established in children below 6 months of age. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

What happens if I take too much Lyby Lotion?

If someone swallows Abametapir by accident, they should get medical advice straight away. Tell them to call their local poison control centre as well. In an emergency call 999 or go to the nearest hospital emergency department.

How should I store Lyby Lotion?

Keep Abametapir at 2° to 8° C, in a place that stays free from frost. Keep it away from light, and keep it out of the reach of children.

Do I need a prescription for Lyby Lotion?

Lyby Lotion is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 15 Aug 2026