More from Loxikam
Other strengths and forms by Opsonin Pharma Limited
Indications & Uses
Loxikam is indicated for:
Pharmacology
Meloxicam belongs to the oxicam group of non-steroidal anti-inflammatory drugs (NSAIDs) and provides anti-inflammatory, pain-relieving and fever-reducing effects. When taken by mouth, it is well absorbed, with an average bioavailability of 89%. At the standard doses of 7.5 mg and 15 mg, blood levels rise in proportion to the dose taken, averaging 0.4 to 1.0 mg/litre with 7.5 mg and 0.8 to 2.0 mg/litre with 15 mg. Once in the bloodstream, meloxicam binds very strongly (about 99%) to plasma proteins, mainly albumin. The body breaks it down extensively in the liver, mainly by oxidising the methyl group attached to its thiazolyl ring, and only about 3% of a dose leaves the body unchanged. The remainder is cleared roughly equally through the urine and the stool, and on average it takes about 20 hours for half of the drug to be eliminated from the body.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For Adults: Osteoarthritis: 7.5 mg per day, which can be raised to 15 mg per day if it doesn't provide enough improvement. Rheumatoid arthritis: 15 mg per day, though elderly patients should keep to 7.5 mg per day for long-term treatment. Ankylosing spondylitis: 15 mg per day, or 7.5 mg per day in elderly patients. The dose should not go above 15 mg/day, and the full daily amount is taken as a single dose. Adults at higher risk of adverse reactions should begin treatment at 7.5 mg/day, and dialysis patients with severe renal failure should not exceed 7.5 mg/day.
For Children: Meloxicam's pharmacokinetics in paediatric patients under 18 years of age have not been studied.
Side Effects
Nausea, vomiting, stomach pain, indigestion, constipation, and diarrhoea can all occur with this medicine. Rarely, it may cause stomach ulcers or gastrointestinal bleeding. Some people may develop a skin rash or hives, and swelling of the lower legs is also possible during treatment. In people who are allergic to aspirin or other NSAIDs, it has been known to trigger an asthma attack. Headache, dizziness, and drowsiness may also occur.
Cautions & Contraindications
Warnings & Precautions
Patients with known cardiovascular disease or CV risk factors, fluid retention or heart failure, or a history of GI bleeding or ulceration. Hepatic and renal impairment. Elderly patients. Pregnancy and lactation.
Contraindications
Meloxicam should not be used by anyone who is hypersensitive to it. It should also be avoided by patients who have developed asthma symptoms, nasal polyps, angioneurotic oedema, or urticaria after taking aspirin or other NSAIDs. It is likewise not recommended for patients with an active peptic ulcer within the past six months or a history of recurrent peptic ulcer disease, severe liver failure, severe kidney failure not managed by dialysis, gastrointestinal bleeding, cerebrovascular bleeding, or other bleeding disorders.
Pregnancy & Breastfeeding
Meloxicam is best avoided during pregnancy. It is also not known whether it passes into breast milk, so nursing mothers should not take it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Meloxicam tablets in a cool, dry place, away from light. Meloxicam suppositories should be stored below 25˚C and protected from light and moisture.
Drug Interactions
Common questions about Loxikam 100 mg
What is Loxikam 100 mg Bolus?
Loxikam 100 mg Bolus is a medicine that contains Meloxicam. It is made by Opsonin Pharma Limited. It belongs to the Drugs for Osteoarthritis group of medicines.
What is Loxikam used for?
Loxikam is used for: Osteoarthritis, Rheumatoid Arthritis.
What are the side effects of Loxikam?
Nausea, vomiting, stomach pain, indigestion, constipation, and diarrhoea can all occur with this medicine. Rarely, it may cause stomach ulcers or gastrointestinal bleeding.
Can I take Loxikam during pregnancy or while breastfeeding?
Meloxicam is best avoided during pregnancy. It is also not known whether it passes into breast milk, so nursing mothers should not take it. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Loxikam?
Keep Meloxicam tablets in a cool, dry place, away from light. Meloxicam suppositories should be stored below 25˚C and protected from light and moisture.
Can I take other medicines with Loxikam?
Some medicines can interact with Meloxicam, for example: Polymyxin B Sulfate, Heparin Sodium, Ticlopidine Hydrochloride, Methotrexate. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Loxikam?
Loxikam is a prescription (Rx) medicine. Take it as your doctor advises.