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Same active ingredient — pay up to 50% less
These brands contain the same active ingredient (Loperamide Hydrochloride). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Lopamid is indicated for:
Pharmacology
Loperamide Hydrochloride slows the movement of the intestine. It acts on the longitudinal and circular smooth muscle, interacting with the cholinergic and noncholinergic neuronal mechanisms that produce the peristaltic reflex, and this reduces peristaltic activity. It binds to the opiate receptor in the gut wall, which reduces propulsive peristalsis and increases intestinal transit time. It also increases the tone of the anal sphincter. This also inhibits electrolyte and fluid secretion in the intestine.
Loperamide Hydrochloride is given by mouth as a capsule. More than 65% is absorbed, at a modest rate, and peak serum levels of 2-3 µgm/litre are reached about 4 hours after the dose. The remaining 35% leaves the body unchanged in the faeces. The medicine goes through extensive presystemic first-pass metabolism in the gut wall and in the liver. Because loperamide has a high affinity for the gut wall and is metabolised before it reaches the circulation, it does not act centrally. This is also why only a very small amount reaches the systemic circulation.
As for elimination, 0.63-1.4% appears in the urine as unchanged drug, 58% is excreted in the bile and 15-23% appears in the faeces.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For acute diarrhoea, adults take 2 capsules of loperamide hydrochloride to start, then 1 capsule after every loose stool. The usual dose is 3 to 4 capsules a day, and the daily maximum should not go above 8 capsules. Children aged 9 to 12 years take 1 capsule after each loose stool until the diarrhoea is controlled, but not more than 6 capsules daily. Children aged 5 to 9 years take 1 capsule 4 times daily until the diarrhoea is controlled, and not more than 4 capsules daily. For chronic diarrhoea, adults take 2 to 4 capsules daily in divided doses, depending on severity. Children take 1 to 2 capsules daily, again depending on severity. The dose can also be whatever the physician directs.
Side Effects
Some people taking Loperamide Hydrochloride have reported abdominal pain and other stomach and bowel disturbances. Dry mouth, dizziness, tiredness and skin rashes have also been reported, among others.
Cautions & Contraindications
Warnings & Precautions
Loperamide Hydrochloride needs to be used with caution in people who have severe liver disturbance.
Contraindications
Loperamide Hydrochloride should not be given to anyone who is hypersensitive to the drug, or to patients who must avoid constipation. It should also not be used alone in acute dysentery, which shows up as blood in the stool and a raised body temperature.
Pregnancy & Breastfeeding
Nobody has established that Loperamide is safe in human pregnancy. As with other drugs, it isn't advisable to give Loperamide during pregnancy. Only an extremely small fraction of Loperamide Hydrochloride passes into human breast milk, but caution is still advised if it is to be given to a nursing mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Taking too much Loperamide Hydrochloride can cause constipation, nausea and CNS depression (a slowing of the central nervous system).
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Loperamide Hydrochloride, like all medicines, out of reach of children. Store it in a cool, dry place and protect it from light.
Common questions about Lopamid 2 mg
What is Lopamid 2 mg Capsule?
Lopamid 2 mg Capsule is a medicine that contains Loperamide Hydrochloride. It is made by The ACME Laboratories Ltd. It belongs to the Anti-diarrhoeal group of medicines.
What is Lopamid used for?
Lopamid is used for: Diarrhea, Inflammatory Bowel Disease.
What are the side effects of Lopamid?
Some people taking Loperamide Hydrochloride have reported abdominal pain and other stomach and bowel disturbances. Dry mouth, dizziness, tiredness and skin rashes have also been reported, among others.
Can I take Lopamid during pregnancy or while breastfeeding?
Nobody has established that Loperamide is safe in human pregnancy. As with other drugs, it isn't advisable to give Loperamide during pregnancy. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Lopamid?
Taking too much Loperamide Hydrochloride can cause constipation, nausea and CNS depression (a slowing of the central nervous system). In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Lopamid?
Keep Loperamide Hydrochloride, like all medicines, out of reach of children. Store it in a cool, dry place and protect it from light.
Is there a cheaper medicine with the same ingredient?
Loramide by Bristol Pharma Ltd. has the same ingredient and strength for ৳0.50 per unit, compared with ৳1.00 for Lopamid. Ask your doctor or pharmacist before switching.
Do I need a prescription for Lopamid?
Lopamid is a prescription (Rx) medicine. Take it as your doctor advises.