Pricing
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Other strengths and forms by Opsonin Pharma Limited
Indications & Uses
Lesterol is indicated for:
Pharmacology
Fluvastatin works by competitively blocking HMG-CoA reductase, the enzyme responsible for cholesterol production. This lowers plasma levels of total cholesterol, triglycerides, LDL, and VLDL, while raising HDL levels.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
General Dosing Information: Fluvastatin is taken by mouth in doses ranging from 20 mg to 80 mg per day, as a single dose, with or without food. Capsules should not be broken, crushed, chewed or opened before use, and two 40 mg Fluvastatin capsules should not be taken at the same time. Because a given dose reaches its full effect within about 4 weeks, lipid levels should be checked again at that point and the dose adjusted based on how the patient responds and on established treatment guidelines.
Adult Patients with Hypercholesterolemia (Heterozygous Familial and Nonfamilial) and Mixed Dyslipidemia: The recommended starting dose is one 40 mg Fluvastatin capsule in the evening, or one 40 mg capsule twice a day; two 40 mg capsules should not be taken at the same time. Alternatively, the recommended starting dose is one 80 mg dose taken once, at any time of day.
Pediatric Patients (10 to 16 years of age) with Heterozygous Familial Hypercholesterolemia: The recommended starting dose is one 20 mg Fluvastatin capsule. Any increase in dose, up to a maximum of 40 mg twice daily or 80 mg once daily, should be made at intervals of 6 weeks, with the dose tailored to the individual patient's treatment goals.
Side Effects
Most commonly, people taking this medicine (in 2% or more of cases, and more often than with a placebo) report headache, indigestion, muscle pain, stomach pain, and nausea.
Cautions & Contraindications
Warnings & Precautions
Skeletal muscle problems such as myopathy and rhabdomyolysis are more likely in people over 65, those with poorly controlled hypothyroidism or impaired kidney function, and those taking cyclosporine or gemfibrozil alongside this medicine. Patients should tell their doctor right away if they notice any signs of muscle problems, and treatment should be stopped if myopathy is diagnosed or suspected. This medicine can also affect the liver, sometimes causing a lasting rise in liver enzyme levels. Liver enzymes should be checked before starting treatment and monitored afterward as the doctor advises.
Contraindications
This medicine should not be used by anyone who is hypersensitive to any of its ingredients or who has active liver disease or unexplained, persistent elevations in liver enzyme (transaminase) levels. It is also not recommended for women who are pregnant or may become pregnant, or for nursing mothers.
Pregnancy & Breastfeeding
Pregnancy: Fluvastatin must not be used by women who are pregnant or who may become pregnant. During a normal pregnancy, blood cholesterol and triglyceride levels rise naturally, and cholesterol (or substances derived from it) is essential for the developing baby. Because of this, Fluvastatin can potentially harm the fetus if taken during pregnancy. Since hardening of the arteries (atherosclerosis) develops slowly over many years, briefly stopping cholesterol-lowering treatment during pregnancy is unlikely to affect the long-term management of high cholesterol. Fluvastatin should only be given to women of childbearing age if pregnancy is highly unlikely, and only after they have been made aware of the possible risks. If a patient becomes pregnant while taking this medicine, it should be stopped right away and she should be informed of the potential risk to her unborn child.
Breastfeeding: Fluvastatin passes into breast milk in animal studies, and because this class of medicines (HMG-CoA reductase inhibitors) can potentially cause serious side effects in nursing infants, mothers who need Fluvastatin treatment should not breastfeed.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Fluvastatin below 30°C, away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Lesterol 20 mg
What is Lesterol 20 mg Capsule?
Lesterol 20 mg Capsule is a medicine that contains Fluvastatin. It is made by Opsonin Pharma Limited. It belongs to the Other Anti-anginal & Anti-ischaemic drugs group of medicines.
What is Lesterol used for?
Lesterol is used for: Hyperlipidemia.
What are the side effects of Lesterol?
Most commonly, people taking this medicine (in 2% or more of cases, and more often than with a placebo) report headache, indigestion, muscle pain, stomach pain, and nausea.
Can I take Lesterol during pregnancy or while breastfeeding?
Pregnancy: Fluvastatin must not be used by women who are pregnant or who may become pregnant. During a normal pregnancy, blood cholesterol and triglyceride levels rise naturally, and cholesterol (or substances derived from it) is essential for the developing baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Lesterol?
Store Fluvastatin below 30°C, away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Lesterol?
Some medicines can interact with Fluvastatin, for example: Cyclosporine, Niacin, Fluconazole, Phenytoin, Glibenclamide, Warfarin Sodium. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Lesterol is already among the lowest-priced brands of Fluvastatin at this strength.
Do I need a prescription for Lesterol?
Lesterol is a prescription (Rx) medicine. Take it as your doctor advises.