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Same active ingredient — pay up to 17% less
These brands contain the same active ingredient (Ledipasvir + Sofosbuvir). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Lesovir-C
Other strengths and forms by Beximco Pharmaceuticals Ltd.
Indications & Uses
Ledipasvir + Sofosbuvir is used to treat chronic hepatitis C (CHC) caused by genotype 1 infection in adults.
Pharmacology
Fixed-dose combination tablet, taken by mouth, containing ledipasvir and sofosbuvir. Ledipasvir works by inhibiting the HCV NS5A protein, while sofosbuvir is a nucleotide analog that inhibits the HCV NS5B polymerase. After an oral dose of this tablet, ledipasvir reaches its median peak blood concentration around 4 to 4.5 hours later.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Recommended dosage: one tablet (90 mg of Ledipasvir and 400 mg of Sofosbuvir) taken by mouth once daily, with or without food. Recommended treatment duration: 12 weeks for treatment-naive patients with or without cirrhosis, 12 weeks for treatment-experienced patients without cirrhosis, and 24 weeks for treatment-experienced patients with cirrhosis. No dosage recommendation can be made for patients with severe renal impairment or end-stage renal disease.
Side Effects
Fatigue, headache, nausea, diarrhoea and insomnia are the most commonly reported side effects with this tablet, each seen in 10% or more of patients (across all severity grades) taking it for 8, 12, or 24 weeks.
Cautions & Contraindications
Warnings & Precautions
Bradycardia with amiodarone coadministration: Patients taking amiodarone may experience serious symptomatic bradycardia, particularly if they are also on beta-blockers or have underlying cardiac conditions and/or advanced liver disease. Taking amiodarone together with this tablet is not recommended. For patients who have no other viable treatment option, cardiac monitoring is advised. Using this medicine with other drugs containing sofosbuvir is also not recommended.
Contraindications
This combination should not be used in patients who are known to be hypersensitive to ledipasvir, sofosbuvir, or any other ingredient in the product.
Pregnancy & Breastfeeding
Pregnancy Category B. Well-controlled human studies of Ledipasvir and Sofosbuvir in pregnancy are lacking, and animal data don't always predict how people will respond, so this combination should be used in pregnancy only if the expected benefit outweighs the possible risk to the baby. Whether Ledipasvir and Sofosbuvir or their breakdown products pass into breast milk is not known.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Pediatric Use: Safety and effectiveness of Ledipasvir and Sofosbuvir have not been established in pediatric patients.
Geriatric Use: Studies and other reported clinical experience have not shown any overall difference in safety or effectiveness between elderly patients and younger ones. So no dosage adjustment of Ledipasvir and Sofosbuvir is needed in geriatric patients.
Storage
Keep Ledipasvir + Sofosbuvir out of the reach of children. Store it in a cool, dry place and protect it from light.
Drug Interactions
Common questions about Lesovir-C 90 mg+400 mg
What is Lesovir-C 90 mg+400 mg Tablet?
Lesovir-C 90 mg+400 mg Tablet is a medicine that contains Ledipasvir + Sofosbuvir. It is made by Beximco Pharmaceuticals Ltd. It belongs to the Hepatic viral infections (Hepatitis C) group of medicines.
What is Lesovir-C used for?
Ledipasvir + Sofosbuvir is used to treat chronic hepatitis C (CHC) caused by genotype 1 infection in adults.
What are the side effects of Lesovir-C?
Fatigue, headache, nausea, diarrhoea and insomnia are the most commonly reported side effects with this tablet, each seen in 10% or more of patients (across all severity grades) taking it for 8, 12, or 24 weeks.
Can I take Lesovir-C during pregnancy or while breastfeeding?
Pregnancy Category B. Well-controlled human studies of Ledipasvir and Sofosbuvir in pregnancy are lacking, and animal data don't always predict how people will respond, so this combination should be used in pregnancy only if the expected benefit outweighs the possible risk to the baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Lesovir-C?
Keep Ledipasvir + Sofosbuvir out of the reach of children. Store it in a cool, dry place and protect it from light.
Can I take other medicines with Lesovir-C?
Some medicines can interact with Ledipasvir + Sofosbuvir, for example: Sofosbuvir, Rifampicin, Amiodarone Hydrochloride. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Dualvir by Aristopharma Limited has the same ingredient and strength for ৳1,000.00 per unit, compared with ৳1,200.00 for Lesovir-C. Ask your doctor or pharmacist before switching.
Do I need a prescription for Lesovir-C?
Lesovir-C is a prescription (Rx) medicine. Take it as your doctor advises.