More from Kacibac
Other strengths and forms by Ziska Pharmaceuticals Ltd.
Indications & Uses
Kacibac is indicated for:
Pharmacology
Amikacin sulfate is a semi-synthetic aminoglycoside antibiotic. In laboratory testing, amikacin is active against pseudomonas species, Escherichia coli, Proteus species, Providencia species, Klebsiella-Enterobacter species, Acinetobacter species, and Citrobacter freundii. When strains of these organisms turn out to be resistant to other aminoglycosides, including gentamicin, tobramycin and kanamycin, many are still susceptible to amikacin. Amikacin sulfate is also active in vitro against penicillinase-producing and nonpenicillinase-producing Staphylococcus species, including methicillin-resistant strains.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage
Adults and children: 15 mg/kg/day given in two equally divided doses (equivalent to 500 mg twice daily in adults). The 100 mg strength is recommended for children so that the appropriate dose can be measured accurately.
Neonates and premature infants: An initial loading dose of 10 mg/kg, followed by 15 mg/kg/day in two equally divided doses.
Elderly: Amikacin is excreted by the renal route. Renal function should be assessed whenever possible, and the dosage adjusted as described under impaired renal function.
Life threatening infections and/or those caused by Pseudomonas: The adult dose may be increased to 500 mg every eight hours, but should neither exceed 1.5 g/day nor be given for longer than 10 days. A maximum total adult dose of 15 g should not be exceeded.
Urinary tract infections (other than pseudomonal infections): 7.5 mg/kg/day in two equally divided doses (equivalent to 250 mg twice daily in adults).
Impaired renal function: In patients with impaired renal function, the daily dose should be reduced and/or the interval between doses increased to avoid accumulation of the drug.
Side Effects
People who have been given Amikin (amikacin) have reported ringing in the ears (tinnitus), vertigo, and deafness that may be partial and reversible or may be irreversible. Other reported effects are skin rash, drug fever, headache, paraesthesia, nausea and vomiting.
Cautions & Contraindications
Warnings & Precautions
Because Amikin reaches high concentrations in the renal excretory system, patients should be kept well hydrated to help minimize chemical irritation of the renal tubules. If azotemia worsens, treatment should be discontinued. Monitoring renal function throughout treatment with aminoglycosides such as Amikin is especially important.
Contraindications
Amikacin Injection should not be used in patients who are known to be hypersensitive to Amikacin or to any of the other ingredients in the injection.
Pregnancy & Breastfeeding
Amikacin passes quickly through the placenta into the baby's circulation and surrounding fluid, and this carries a possible risk of hearing damage to the unborn child. It isn't known whether this medicine is safe to use while breastfeeding, as there isn't enough information available.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Pediatric Use: Kacin for injection hasn't been proven safe or effective in children or adolescents under 16 years.
Overdose
If someone takes too much Kacin, or has a toxic reaction to it, peritoneal dialysis or haemodialysis can help clear the medicine from the blood.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Amikacin below 30°C, away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Kacibac 500 mg
What is Kacibac 500 mg Injection?
Kacibac 500 mg Injection is a medicine that contains Amikacin. It is made by Ziska Pharmaceuticals Ltd. It belongs to the Aminoglycosides group of medicines.
What is Kacibac used for?
Kacibac is used for: Sepsis.
What are the side effects of Kacibac?
People who have been given Amikin (amikacin) have reported ringing in the ears (tinnitus), vertigo, and deafness that may be partial and reversible or may be irreversible. Other reported effects are skin rash, drug fever, headache, paraesthesia, nausea and vomiting.
Can I take Kacibac during pregnancy or while breastfeeding?
Amikacin passes quickly through the placenta into the baby's circulation and surrounding fluid, and this carries a possible risk of hearing damage to the unborn child. It isn't known whether this medicine is safe to use while breastfeeding, as there isn't enough information available. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Kacibac?
If someone takes too much Kacin, or has a toxic reaction to it, peritoneal dialysis or haemodialysis can help clear the medicine from the blood. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Kacibac?
Store Amikacin below 30°C, away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Kacibac?
Some medicines can interact with Amikacin, for example: Polymyxin B Sulfate, Carica Papaya Leaf Extract. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Kacibac?
Kacibac is a prescription (Rx) medicine. Take it as your doctor advises.