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Rx11% • Emulsion for infusion
Indications & Uses
This parenteral nutrition is for patients and children above 2 years of age when oral or enteral feeding is impossible, not enough or contraindicated.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Detailed dosing reference is not available yet. Please follow your prescription and consult your pharmacist.
Side Effects
Glucose with Vamin and Intralipid, given as an infusion, can cause a rise in body temperature (incidence <3%). Less often, people have shivering, chills, and nausea or vomiting (incidence <1%). Transient increases in liver enzymes have also been reported during intravenous nutrition. Reports of other undesirable effects linked to the components in this infusion are extremely rare. They include hypersensitivity reactions (anaphylactic reaction, skin rash, urticaria), respiratory symptoms (for example tachypnoea), and hypertension or hypotension. Haemolysis, reticulocytosis, abdominal pain, headache, nausea, vomiting, tiredness and priapism have also been reported.
Cautions & Contraindications
Warnings & Precautions
Check how well the body can clear fat. The way to do this is to measure serum triglycerides after a fat-free period of 5 to 6 hours. During the infusion, the serum triglyceride level should not go above 3 mmol/l. Choose the bag size with care, especially the volume and the quantitative composition. For children, adjust these volumes to their hydration and nutritional status. One reconstituted bag is for single use only. Correct any disturbance of electrolyte and fluid balance (e.g. abnormally high or low serum electrolyte levels) before starting the infusion. Special clinical monitoring is needed at the start of any intravenous infusion, and if any abnormal sign appears, the infusion must be stopped. Using any central vein carries an increased risk of infection, so keep strict aseptic precautions to avoid contamination while the catheter is inserted and handled. Give this solution with caution where lipid metabolism is impaired because of renal insufficiency, uncompensated diabetes mellitus, pancreatitis, impaired liver function, or hypothyroidism with hypertriglyceridemia or sepsis. If it is given to patients with these conditions, close monitoring of serum triglyceride concentrations is mandatory.
Contraindications
Glucose, Vamin Novum and Intralipid must not be used in people who are hypersensitive to egg, soya or peanut protein, or to any of the active substances or excipients. They are also contraindicated in severe hyperlipaemia, severe liver insufficiency, severe blood coagulation disorders and inborn errors of amino acid metabolism. Severe renal insufficiency is a contraindication too, unless haemofiltration or dialysis is available. The same applies to acute shock, to hyperglycemia that requires more than 6 units insulin/h, and to pathologically elevated serum levels of any of the included electrolytes. The general contra-indications to infusion therapy also apply: acute pulmonary oedema, hyper hydration, decompensated cardiac insufficiency and hypotonic dehydration. Haemophagocytotic syndrome is another contraindication. Unstable conditions rule out its use as well (e.g. severe post-traumatic conditions, uncompensated diabetes, acute myocardial infarction, metabolic acidosis, severe sepsis and hyperosmolar coma). It must not be given to infants under 2 years of age.
Overdose
Some people have felt nausea, vomiting and sweating when amino acids were infused faster than the recommended maximum rate. If the body can't clear fat properly, fat overload syndrome can develop. This can happen with an overdose, but it can also happen at the recommended infusion rates when the patient's condition changes suddenly, for example with impaired kidney function or an infection.
Fat overload syndrome shows up as hyperlipaemia, fever, fat infiltration, hepatomegaly, splenomegaly, anaemia, leucopenia, thrombocytopenia, blood coagulation disorders and coma. These changes are always reversible once the fat infusion is stopped.
If symptoms of overdose appear, the infusion should be slowed down or stopped. In some rare serious cases, haemodialysis, haemofiltration or haemo-diafiltration may be necessary.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store at 25°C and don't freeze it. Storing it this way is recommended.
Drug Interactions
Common questions about Kabiven Perifer 11%
What is Kabiven Perifer 11% Emulsion for infusion?
Kabiven Perifer 11% Emulsion for infusion is a medicine that contains Glucose 11% + Vamin 18 Novum + Intralipid 20%. It is made by Radiant Pharmaceuticals Ltd. It belongs to the Parenteral nutritional preparations group of medicines.
What is Kabiven Perifer used for?
This parenteral nutrition is for patients and children above 2 years of age when oral or enteral feeding is impossible, not enough or contraindicated.
What are the side effects of Kabiven Perifer?
Glucose with Vamin and Intralipid, given as an infusion, can cause a rise in body temperature (incidence <3%). Less often, people have shivering, chills, and nausea or vomiting (incidence <1%).
What happens if I take too much Kabiven Perifer?
Some people have felt nausea, vomiting and sweating when amino acids were infused faster than the recommended maximum rate. If the body can't clear fat properly, fat overload syndrome can develop. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Kabiven Perifer?
Store at 25°C and don't freeze it. Storing it this way is recommended.
Can I take other medicines with Kabiven Perifer?
Some medicines can interact with Glucose 11% + Vamin 18 Novum + Intralipid 20%, for example: Warfarin Sodium. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Kabiven Perifer?
Kabiven Perifer is a prescription (Rx) medicine. Take it as your doctor advises.