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Other brands with the same active ingredient
These brands contain the same active ingredient (Itopride Hydrochloride). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Itofix 50 is indicated for:
Pharmacology
Itopride Hydrochloride is a strong dopamine-2 antagonist and also an acetylcholine esterase inhibitor. It raises acetylcholine levels by blocking dopamine D2 receptors and by inhibiting acetylcholinesterase. With more acetylcholine available, Gl peristalsis increases and the pressure of the lower esophageal sphincter goes up. Gastric motility is stimulated, gastric emptying speeds up, and gastro-duodenal coordination improves.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual adult dose of Itopride Hydrochloride is 50 mg by mouth, three times daily. The dose may be reduced depending on the patient's age and symptoms. Itopride Hydrochloride should be taken before meals.
Use in the elderly
Elderly people often have reduced body function, so they are prone to adverse reactions and should be closely monitored. If adverse reactions appear, suitable steps should be taken, such as reducing the dose or stopping the medicine.
Use in pediatric population
The safety and efficacy of Itopride Hydrochloride in children and adolescents have not been established. For this reason, it is not recommended for anyone below 18 years of age.
Shock and anaphylactoid reactions
Shock and anaphylactoid reactions may occur, so the patient should be watched closely. If hypotension, dyspnoea, larynx edema, urticaria, pallor, diaphoresis etc. occur, stop the medicine and take appropriate measures.
Hepatic function disorder and Jaundice
Hepatic function disorder and jaundice may occur, with increased AST (GOT), ALT (GPT) and g-GTP etc. The patient should be closely observed. If any abnormalities occur, stop the medicine and take appropriate therapeutic measures.
Side Effects
Side-effect information is not available for this brand yet.
Cautions & Contraindications
Warnings & Precautions
Take care when using Itopride Hydrochloride, because it increases the action of acetylcholine. If a person's stomach and bowel symptoms have not improved, Itopride Hydrochloride should not be taken continuously for a long time. Precautions concerning use When the medicine is given to a patient in a press-through package (PTP), tell the patient to take the tablet out of the package before swallowing it. There are reports that people have swallowed the PTP sheet by accident, and its hard, sharp corners can puncture the lining of the food pipe (esophageal mucosa). In some cases this has gone on to perforation, which led to serious complications such as mediastinal sinusitis.
Contraindications
Itopride Hydrochloride must not be given to anyone who is hypersensitive to the active substance or to any of the excipients in the preparation. It should also not be used in patients for whom increased gastrointestinal motility could be harmful, for example those with gastrointestinal haemorrhage, mechanical obstruction or perforation.
Pregnancy & Breastfeeding
Nobody has verified whether Itopride Hydrochloride is safe in pregnancy. So it can be given to a pregnant woman, or to a woman who may be pregnant, only when the expected benefit clearly outweighs the possible risk.
Information on how much passes into mother's milk comes from animals only. There is not enough experience of using itopride during breast-feeding, so it is not recommended for women who are breast-feeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
If someone takes a very large overdose of Itopride Hydrochloride, the usual measures of gastric lavage and symptomatic treatment should be applied.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Itopride Hydrochloride below 30°C, in a cool and dry place, and away from light. Keep all the medicine out of the reach of children.
Common questions about Itofix 50 50 mg
What is Itofix 50 50 mg Tablet?
Itofix 50 50 mg Tablet is a medicine that contains Itopride Hydrochloride. It is made by Kumudini Pharma Ltd. It belongs to the Osmotic purgatives group of medicines.
What is Itofix 50 used for?
Itofix 50 is used for: Pain, Gastroesophageal Reflux Disease, Nausea and Vomiting.
Can I take Itofix 50 during pregnancy or while breastfeeding?
Nobody has verified whether Itopride Hydrochloride is safe in pregnancy. So it can be given to a pregnant woman, or to a woman who may be pregnant, only when the expected benefit clearly outweighs the possible risk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Itofix 50?
If someone takes a very large overdose of Itopride Hydrochloride, the usual measures of gastric lavage and symptomatic treatment should be applied. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Itofix 50?
Keep Itopride Hydrochloride below 30°C, in a cool and dry place, and away from light. Keep all the medicine out of the reach of children.
Do I need a prescription for Itofix 50?
Itofix 50 is a prescription (Rx) medicine. Take it as your doctor advises.