Indications & Uses
Iprost is indicated for:
Pharmacology
Latanoprost is an analogue of prostaglandin F2α. It acts as a selective prostanoid FP receptor agonist and is believed to lower intraocular pressure (IOP) by increasing the outflow of aqueous humor. Studies in both animals and humans suggest that this effect works mainly by increasing uveoscleral outflow. Elevated IOP is a major risk factor for glaucomatous field loss: the higher the IOP, the greater the likelihood of optic nerve damage and visual field loss.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual dose of Latanoprost is 1 drop (1.5 mcg) in the affected eye or eyes, once a day in the evening.
Side Effects
Eyelash changes (increased length, thickness, pigmentation, and number of lashes), darkening of the eyelid skin, intraocular inflammation (iritis/uveitis), changes in iris pigmentation, and macular edema, including cystoid macular edema, have been reported. In 6 month, multicenter, double masked, active controlled trials of Remaprost, 5 to 15% of patients experienced ocular adverse events and signs and symptoms such as blurred vision, burning and stinging, conjunctival hyperemia, a foreign body sensation, itching, increased iris pigmentation, and punctate epithelial keratopathy. Local conjunctival hyperemia was also observed; however, fewer than 1% of patients treated with Remaprost had to stop therapy because they could not tolerate this hyperemia.
Cautions & Contraindications
Warnings & Precautions
Ophthalmic Solution may cause the iris to gradually turn a darker shade over time. This happens because the melanocytes (pigment-producing cells) in the iris's stromal layer start producing more melanin, not because the number of these cells increases. In clinical trials, this browning effect did not continue to worsen after treatment was stopped, but the change in eye colour itself appears to be permanent. Some patients also notice darkening of the eyelid skin, which tends to fade back to normal once treatment ends. Eyelashes may become longer, thicker, more numerous, more pigmented, or grow in an irregular direction; these lash changes are usually reversible after stopping the medicine. This medicine should be used cautiously in patients with a history of intraocular inflammation (iritis or uveitis), and it is generally best avoided in those with active inflammation in the eye. Remaprost should also be used with caution in patients whose posterior lens capsule is not intact, or who have known risk factors for macular edema.
Contraindications
Known hypersensitivity to latanoprost, benzalkonium chloride, or any other ingredient in this product.
Pregnancy & Breastfeeding
Latanoprost is listed as Pregnancy Category C. There are no adequate and well controlled studies in pregnant women, so we don't have solid evidence on its safety in pregnancy. Because of this, it should be used during pregnancy only when the possible benefit to the mother outweighs the possible risk to the baby.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Until you open the cap, keep the Latanoprost bottle in its box in a refrigerator (2°-8° C), away from light. Once it's opened, keep the bottle in its box in a cool place below 25° C. Use the contents within one month after the dropper is opened. Keep the medicine out of reach of children.
Drug Interactions
Common questions about Iprost 5 mg
What is Iprost 5 mg Eye Drops?
Iprost 5 mg Eye Drops is a medicine that contains Latanoprost. It is made by Apex Pharma Ltd. It belongs to the Drugs for miotics and glaucoma group of medicines.
What is Iprost used for?
Iprost is used for: Hypertension, Glaucoma.
What are the side effects of Iprost?
Eyelash changes (increased length, thickness, pigmentation, and number of lashes), darkening of the eyelid skin, intraocular inflammation (iritis/uveitis), changes in iris pigmentation, and macular edema, including cystoid macular edema, have been reported. In 6 month, multicenter, double masked, active controlled trials of Remaprost, 5 to 15% of patients experienced ocular adverse events and signs and symptoms such as blurred vision, burning and stinging, conjunctival hyperemia, a foreign body sensation, itching, increased iris pigmentation, and punctate epithelial keratopathy.
Can I take Iprost during pregnancy or while breastfeeding?
Latanoprost is listed as Pregnancy Category C. There are no adequate and well controlled studies in pregnant women, so we don't have solid evidence on its safety in pregnancy. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Iprost?
Until you open the cap, keep the Latanoprost bottle in its box in a refrigerator (2°-8° C), away from light. Once it's opened, keep the bottle in its box in a cool place below 25° C.
Can I take other medicines with Iprost?
Some medicines can interact with Latanoprost, for example: Latanoprost + Timolol. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Iprost?
Iprost is a prescription (Rx) medicine. Take it as your doctor advises.