Pricing
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Insulet ASP is indicated for:
Pharmacology
Insulin Aspart mainly works by regulating how the body handles glucose. It binds to the insulin receptors on muscle and fat cells, and this lowers blood glucose in two ways: it helps the cells take up glucose, and at the same time it reduces the amount of glucose the liver puts out.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Insulin Aspart starts working faster and acts for a shorter time than soluble human insulin. Because of this, it should generally be given immediately before a meal. When necessary, it may be given soon after a meal.
The dosage is individual, and the physician decides it according to the patient's needs. Insulin Aspart should normally be used together with a long-acting insulin given at least once a day. The individual insulin requirement is usually between 0.5 and 1.0 IU/kg/day in adults and children over 2 years of age. In a meal-related treatment, 50 to 70% of this requirement may be provided by Insulin Aspart and the rest by the long-acting insulin. The dosage may also need adjusting if the patient does more physical activity or changes the usual diet. Exercise straight after a meal may increase the risk of hypoglycaemia.
Subcutaneous injection: it should be injected into the abdominal region, buttocks, thigh or upper arm. Its onset is more rapid and its activity shorter than human regular insulin, so inject it immediately (within 5 to 10 minutes) before a meal.
Continuous Subcutaneous Insulin Infusion (CSII) by external pump: Insulin Aspart can also be infused subcutaneously by an external insulin pump. The initial programming of the pump should be based on the total daily insulin dose of the previous regimen. Approximately 50% of the total dose is usually given as meal-related boluses of Insulin Aspart, and the remainder is given as a basal infusion. When it is used with an infusion pump, it should not be mixed with any other insulin.
Intravenous use: Insulin Aspart can be given intravenously under medical supervision for glycemic control. Blood glucose and potassium levels must be monitored closely to avoid hypoglycemia and hypokalemia. For intravenous use, the concentration should be from 0.05 IU/mL to 1.0 IU/mL insulin aspart in infusion systems using polypropylene infusion bags. It has been shown to be stable in infusion fluids such as 0.9% sodium chloride.
Side Effects
People using Insulin Aspart [Protamine Crystallised] may get hypoglycemia, allergic reactions, a reaction at the injection site, lipodystrophy, pruritus and rash.
Cautions & Contraindications
Warnings & Precautions
Dose adjustment and monitoring Anyone treated with insulin should have their blood glucose monitored. If the regimen of Insulin Aspart [Protamine Crystallised] needs to change, make the change carefully and only under medical supervision.
Pregnancy & Breastfeeding
Protamine Crystallised Insulin Aspart is in pregnancy category B. During breastfeeding there are no restrictions on using it, and insulin treatment of a nursing mother should not affect the baby. The dose may still need to be adjusted, though.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
No single dose of insulin can be called an overdose. But if the dose is too high for what the patient needs, hypoglycaemia can develop in stages. With Insulin Aspart [Protamine Crystallised], mild episodes can be treated by giving glucose or sugary products by mouth.
In a severe episode, where the patient has become unconscious, glucagon (0.5 to 1 mg) can be given intramuscularly or subcutaneously. If the patient doesn't respond to glucagon within 10 to 15 minutes, glucose must also be given intravenously. Once the patient regains consciousness, oral carbohydrate is recommended to prevent a relapse.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Drug Interactions
Common questions about Insulet ASP 100 IU/ml
What is Insulet ASP 100 IU/ml SC Injection?
Insulet ASP 100 IU/ml SC Injection is a medicine that contains Insulin Aspart [Protamine Crystallised]. It is made by Aristopharma Limited. It belongs to the Rapid Acting Insulin group of medicines.
What is Insulet ASP used for?
Insulet ASP is used for: Diabetes Mellitus.
What are the side effects of Insulet ASP?
People using Insulin Aspart [Protamine Crystallised] may get hypoglycemia, allergic reactions, a reaction at the injection site, lipodystrophy, pruritus and rash.
Can I take Insulet ASP during pregnancy or while breastfeeding?
Protamine Crystallised Insulin Aspart is in pregnancy category B. During breastfeeding there are no restrictions on using it, and insulin treatment of a nursing mother should not affect the baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Insulet ASP?
No single dose of insulin can be called an overdose. But if the dose is too high for what the patient needs, hypoglycaemia can develop in stages. In an emergency call 999 or go to the nearest hospital emergency department.
Can I take other medicines with Insulet ASP?
Some medicines can interact with Insulin Aspart [Protamine Crystallised], for example: Disopyramide, Pentoxifylline, Danazol, Fluoxetine, Clonidine Hydrochloride, Insulin (Human) 30/70. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Insulet ASP?
Insulet ASP is a prescription (Rx) medicine. Take it as your doctor advises.