Pricing
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All price changes →Indications & Uses
Instasia is indicated for:
Pharmacology
When this gel is used as directed, numbness starts quickly (in about 30 seconds) and usually lasts 30 to 60 minutes. The three medicines in the combination (Benzocaine, Butamben and Tetracaine HCI) each add something different to this. Benzocaine acts fast but wears off soon. Tetracaine HCI is slow to start but works for much longer, and Butamben sits in between, bridging the two with its intermediate action.
All of these agents are believed to work by blocking nerve conduction, and the block is reversible. How fast and how long each one acts depends on how well the mucous membrane absorbs it. After the body has metabolised the medicine, it is excreted in the urine.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Squeeze the tube gently to dispense 200 mg of the gel, which is a bead about ¼ to ½ inches long. Spread it thinly and evenly over the area with a cotton swab. Applying more than 400 mg of gel is contraindicated.
The tissue doesn't need to be dried first. Apply the gel directly to the site where pain control is needed. Anesthesia starts within one minute and lasts for about thirty minutes.
Reduce the dose in the debilitated elderly, in acutely ill patients and in very young patients. An appropriate pediatric dosage has not been established for this topical gel.
Pediatric Use: The safety and effectiveness of this gel in pediatric patients have not been established.
Side Effects
Serious unpredictable reactions to this combination of Benzocaine, Butamben and Tetracaine Hydrochloride, including hypersensitivity and anaphylaxis, are extremely rare. Localized allergic reactions may occur after prolonged or repeated use of any aminobenzoate anesthetic. The most common adverse reaction caused by local anesthetics is contact dermatitis, which shows as erythema and pruritus and may progress to vesiculation and oozing. It happens most often in patients after prolonged self-medication, which is contraindicated. If rash, urticaria, edema or other signs of allergy develop during use, the medicine should be stopped. To lower the chance of a serious allergic reaction, this topical gel should not be applied for prolonged periods unless the patient is under continual supervision. Prolonged contact may also cause dehydration of the epithelium or an escharotic effect.
Cautions & Contraindications
Warnings & Precautions
Methemoglobinemia has been reported on rare occasions with products that contain benzocaine, so take care not to go over the maximum recommended dose. If a patient turns cyanotic, treat it appropriately to counteract the problem, for example with methylene blue if it is medically indicated.
Contraindications
This gel is for topical use only and must never be used for injection. Don't use it on the eyes. It shouldn't be put on large areas of denuded or inflamed tissue either, because too much of the medicine can then be absorbed into the body. Don't give this gel to patients who are hypersensitive to any of its ingredients, or to patients known to have cholinesterase deficiencies. Tolerance may vary with the status of the patient. Don't use the gel under dentures or cotton rolls. If the active ingredients stay trapped under a denture or a cotton roll, they could possibly cause an escharotic effect. As with any topical anesthetic, the usual routine precautions should be followed when using this gel.
Pregnancy & Breastfeeding
Nobody has established whether this gel (benzocaine, butamben and tetracaine hydrochloride) is safe for the development of the baby in the womb. So it should not be used in early pregnancy, unless a physician judges that the possible benefits outweigh the unknown risks. The usual precautions that apply to any topical anesthetic should also be followed when using this gel.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep the medicine in a cool, dry place and away from light. Make sure children can't reach it.
Common questions about Instasia 14%+2%+2%
What is Instasia 14%+2%+2% Topical Gel?
Instasia 14%+2%+2% Topical Gel is a medicine that contains Benzocaine + Butamben + Tetracaine Hydrochloride. It is made by Ziska Pharmaceuticals Ltd. It belongs to the Topical Local Anesthetics group of medicines.
What is Instasia used for?
Instasia is used for: Pain.
What are the side effects of Instasia?
Serious unpredictable reactions to this combination of Benzocaine, Butamben and Tetracaine Hydrochloride, including hypersensitivity and anaphylaxis, are extremely rare. Localized allergic reactions may occur after prolonged or repeated use of any aminobenzoate anesthetic.
Can I take Instasia during pregnancy or while breastfeeding?
Nobody has established whether this gel (benzocaine, butamben and tetracaine hydrochloride) is safe for the development of the baby in the womb. So it should not be used in early pregnancy, unless a physician judges that the possible benefits outweigh the unknown risks. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Instasia?
Keep the medicine in a cool, dry place and away from light. Make sure children can't reach it.
Do I need a prescription for Instasia?
Instasia is a prescription (Rx) medicine. Take it as your doctor advises.