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Other strengths and forms by Incepta Pharmaceuticals Ltd.
Indications & Uses
Hyronate is indicated for:
Pharmacology
Sodium Hyaluronate is a viscous solution made from a high molecular weight fraction of purified natural sodium hyaluronate in buffered physiological sodium phosphate, with a pH of 6.8 to 7.5. Hyaluronic acid is an important component of the body's extracellular matrix and is found in particularly high concentration in cartilage and synovial fluid. Endogenous hyaluronic acid gives synovial fluid its viscosity and elasticity, which is fundamental to its lubricating and shock absorbing properties, and it is essential for the correct structure of proteoglycans in articular cartilage. In osteoarthritis, the amount of hyaluronic acid in synovial fluid and cartilage becomes insufficient and its quality changes. Administering hyaluronic acid directly into arthritic joints improves joint function.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage: Sodium Hyaluronate is given by intra-articular injection. A treatment cycle consists of five injections given at weekly intervals. Some patients may benefit from three injections given at weekly intervals. Inject the full 2 ml into one knee only. If both knees are being treated, use a separate injection for each knee. Treatment may be repeated, usually at an interval of 6 to 12 months.
Pediatrics: The safety and effectiveness of Sodium Hyaluronate have not been demonstrated in children.
Side Effects
Local reactions such as pain, swelling or fluid build-up, warmth, or redness at the injection site have been reported. These symptoms are usually temporary and clear up on their own within a few days when the affected joint is rested and ice is applied.
Cautions & Contraindications
Warnings & Precautions
Take care when injecting Hyalgun into patients who are allergic to avian proteins, feathers, or egg products. A strict aseptic technique must be followed during administration. If joint effusion is present, it should be removed before Hyalgun is injected. For 48 hours after the intra-articular injection, patients are advised to avoid strenuous activities and prolonged (more than 1 hour) weight-bearing activities such as jogging or tennis.
Contraindications
Sodium hyaluronate must not be used in people with a known allergy to hyaluronate preparations. Injections into a joint should also be avoided when there is a current or previous infection, or a skin condition, at or around the injection site, as this lowers the risk of septic arthritis (infection within the joint).
Pregnancy & Breastfeeding
Pregnancy and breastfeeding data for Sodium Hyaluronate are limited: its safety and effectiveness have not been formally established in pregnant women, and it is not known whether it passes into human breast milk. Safety and effectiveness in breastfeeding mothers have likewise not been established.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Sodium Hyaluronate injection in a cool, dry place, below 25° C, and away from light. Don't let it freeze.
Drug Interactions
Common questions about Hyronate 0.1%
What is Hyronate 0.1% Ophthalmic Solution?
Hyronate 0.1% Ophthalmic Solution is a medicine that contains Sodium Hyaluronate. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Drugs for Dry eyes group of medicines.
What is Hyronate used for?
Hyronate is used for: Pain, Osteoarthritis.
What are the side effects of Hyronate?
Local reactions such as pain, swelling or fluid build-up, warmth, or redness at the injection site have been reported. These symptoms are usually temporary and clear up on their own within a few days when the affected joint is rested and ice is applied.
Can I take Hyronate during pregnancy or while breastfeeding?
Pregnancy and breastfeeding data for Sodium Hyaluronate are limited: its safety and effectiveness have not been formally established in pregnant women, and it is not known whether it passes into human breast milk. Safety and effectiveness in breastfeeding mothers have likewise not been established. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Hyronate?
Keep Sodium Hyaluronate injection in a cool, dry place, below 25° C, and away from light. Don't let it freeze.
Can I take other medicines with Hyronate?
Some medicines can interact with Sodium Hyaluronate, for example: Hyaluronic Acid. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Hyronate?
Hyronate is a prescription (Rx) medicine. Take it as your doctor advises.