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Other brands with the same active ingredient
These brands contain the same active ingredient (Hydroxyzine Hydrochloride). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Pharmacology
Hydroxyzine hydrochloride is an anxiolytic antihistamine belonging to the piperazine class, and it works by blocking H1 receptors. It is not a cortical depressant; rather, its effect appears to come from suppressing activity in certain key regions of the subcortical central nervous system. Experimental studies have shown it to produce mild skeletal muscle relaxation. Its bronchodilator, antihistaminic, and pain-relieving effects have likewise been demonstrated experimentally and confirmed in clinical use. An antiemetic effect has also been shown, using both the apomorphine test and the veriloid test. Taken orally, hydroxyzine is absorbed quickly from the gastrointestinal tract, and its clinical effects are usually felt within 15 to 30 minutes.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For symptomatic relief of anxiety and tension: Adults, 50 to 100 mg 4 times daily. Children over 6 years, 50 to 100 mg (5 to 10 teaspoonfuls) daily in divided doses. Children under 6 years, 50 mg (5 teaspoonfuls) daily in divided doses.
Pruritus due to allergic conditions: Adults, 25 mg 3 to 4 times daily. Children over 6 years, 50 to 100 mg (5 to 10 teaspoonfuls) daily in divided doses. Children under 6 years, 50 mg (5 teaspoonfuls) daily in divided doses.
As a sedative, for premedication and following general anesthesia: Adults, 50 to 100 mg. Children, 0.6 mg per kg of body weight.
Side Effects
Side effects reported with the use of Urtizin Hhydrochloride are usually mild and short-lived. The more common ones include drowsiness, headache, and impaired coordination, along with antimuscarinic effects such as urinary retention, dry mouth, blurred vision, and gastrointestinal upset. Rare side effects associated with antihistamines include low blood pressure, palpitations, irregular heartbeat, extrapyramidal effects, dizziness, confusion, depression, sleep disturbances, tremor, convulsions, hypersensitivity reactions (including bronchospasm, angioedema, anaphylaxis, rashes, and photosensitivity reactions), blood disorders, liver dysfunction, and angle-closure glaucoma.
Cautions & Contraindications
Warnings & Precautions
The potentiating action of Urtizin must be considered when the drug is used in conjunction with central nervous system depressants such as narcotics, non-narcotic analgesics, and barbiturates. Therefore, when central nervous system depressants are administered concomitantly with Urtizin, their dosage should be reduced. Since drowsiness may occur with the use of Urtizin, patients should be warned of this possibility and cautioned against driving a car or operating dangerous machinery while taking Urtizin. Patients should be advised against the simultaneous use of other CNS depressant drugs and cautioned that the effect of alcohol may be increased.
Contraindications
Hydroxyzine should not be used by anyone who is hypersensitive to hydroxyzine itself or to any of the ingredients in its formulation.
Pregnancy & Breastfeeding
Hydroxyzine Hydrochloride has not been studied well enough in people to show that it is safe in early pregnancy. Until better data are available, it should not be used in early pregnancy. It is not known whether this medicine passes into breast milk. Many drugs do pass into breast milk, so Hydroxyzine Hydrochloride should not be given to mothers who are breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Use in renal impairment patient: Patients with renal impairment should be given half of the normal dose of Hydroxyzine Hydrochloride.
Use in the elderly patient: In elderly patients, start with half the recommended dose, because the action of the medicine is prolonged.
Overdose
Hypersedation is the most common sign of a Hydroxyzine Hydrochloride overdose. As with any overdose, other drugs may have been taken as well, so the doctor should bear that in mind.
If the patient hasn't vomited on their own, vomiting should be induced. Gastric lavage is also recommended straight away. The patient needs general supportive care, which means checking the vital signs often and watching them closely. Hypotension is unlikely, but if it happens it may be controlled with intravenous fluids and Levarterenol or Metaraminol. Epinephrine should not be used, because Hydroxyzine Hydrochloride counteracts its pressor action.
There is no specific antidote. Hemodialysis is unlikely to help in an overdose of Hydroxyzine Hydrochloride. But if other agents such as barbiturates were taken at the same time, hemodialysis may be indicated. There is also no practical method to measure the amount of Hydroxyzine Hydrochloride in body fluids or tissue after it has been taken or given.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Hydroxyzine Hydrochloride in a cool, dry place and away from light. Make sure children can't reach it.
Drug Interactions
Common questions about Hydrozin 25 25 mg
What is Hydrozin 25 25 mg Tablet?
Hydrozin 25 25 mg Tablet is a medicine that contains Hydroxyzine Hydrochloride. It is made by Albion Laboratories Ltd. It belongs to the Sedating Anti-histamine group of medicines.
What is Hydrozin 25 used for?
Hydrozin 25 is used for: Urticaria, Anxiety.
What are the side effects of Hydrozin 25?
Side effects reported with the use of Urtizin Hhydrochloride are usually mild and short-lived. The more common ones include drowsiness, headache, and impaired coordination, along with antimuscarinic effects such as urinary retention, dry mouth, blurred vision, and gastrointestinal upset.
Can I take Hydrozin 25 during pregnancy or while breastfeeding?
Hydroxyzine Hydrochloride has not been studied well enough in people to show that it is safe in early pregnancy. Until better data are available, it should not be used in early pregnancy. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Hydrozin 25?
Hypersedation is the most common sign of a Hydroxyzine Hydrochloride overdose. As with any overdose, other drugs may have been taken as well, so the doctor should bear that in mind. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Hydrozin 25?
Keep Hydroxyzine Hydrochloride in a cool, dry place and away from light. Make sure children can't reach it.
Can I take other medicines with Hydrozin 25?
Some medicines can interact with Hydroxyzine Hydrochloride, for example: Belladonna, Pethidine, Atropine Sulphate. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Hydrozin 25?
Hydrozin 25 is a prescription (Rx) medicine. Take it as your doctor advises.