Indications & Uses
Hydroxychloroquine Sulfate 300 is indicated for:
Pharmacology
Hydroxychloroquine Sulphate is a synthetic version of quinine. It works as an immunosuppressant by reducing the body's production of rheumatoid factor and acute phase reactants. The drug also builds up inside white blood cells, where it stabilizes lysosomal membranes and blocks the activity of several enzymes, including collagenase and the proteases responsible for cartilage breakdown. Against malaria, it acts by disrupting the cell walls of infected red blood cells, killing the parasites as they develop.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Hydroxychloroquine Sulphate tablets are taken by mouth, and it's best to take them with food to help avoid an upset stomach. For acute and chronic rheumatoid arthritis, the usual dose is 400 to 600 mg daily; once a good response is achieved, which is usually within 4 to 8 weeks, the dose can be reduced to 50%. For Systemic Lupus Erythematosus (SLE), the dose is 400 mg once or twice daily for several weeks or months depending on how the patient responds, with a maintenance dose of 200 to 400 mg daily. For malaria in adults, an initial dose of 800 mg is given, followed by 400 mg after 6 to 8 hours, and then 400 mg on each of the next two consecutive days. In children, a total dose equal to 25 mg/kg is given over 3 days as follows: the first dose is 10 mg base/kg, not exceeding a single dose of 620 mg base; the second dose is 5 mg base/kg, not exceeding a single dose of 310 mg base, given 6 hours after the first dose; the third dose is 5 mg base/kg given 18 hours after the second dose; and the fourth dose is 5 mg base/kg given 24 hours after the third dose.
Side Effects
Roxiquin is generally well tolerated. A few side effects may appear during the first several days, including nausea, vomiting, an upset stomach, loss of appetite, diarrhea, tiredness, weakness, headache, or visual disturbances.
Cautions & Contraindications
Warnings & Precautions
Children are especially sensitive to the effects of 4-aminoquinoline compounds, so patients should be strongly cautioned to keep this medicine well out of children's reach. An ophthalmologic examination is recommended every 12 months.
Contraindications
Hydroxychloroquine sulfate should not be used by anyone with a known allergy to hydroxychloroquine or to any of the other ingredients in this product.
Pregnancy & Breastfeeding
During pregnancy, use this drug only if clearly needed. Since small amounts pass into breast milk, consult your doctor before use.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Use in children and adolescents: the dose and administration section gives the details for this age group.
Overdose
An overdose of hydroxychloroquine sulphate can cause headache, drowsiness, visual disturbances, cardiovascular collapse and convulsions. These can be followed by sudden and early respiratory and cardiac arrest. Treatment is gastric lavage, continued until the stomach is completely emptied.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Hydroxychloroquine Sulphate below 30°C, away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Hydroxychloroquine Sulfate 300 300 mg
What is Hydroxychloroquine Sulfate 300 300 mg Tablet?
Hydroxychloroquine Sulfate 300 300 mg Tablet is a medicine that contains Hydroxychloroquine Sulphate. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Anti-malarial drugs group of medicines.
What is Hydroxychloroquine Sulfate 300 used for?
Hydroxychloroquine Sulfate 300 is used for: Rheumatoid Arthritis, Malaria.
What are the side effects of Hydroxychloroquine Sulfate 300?
Roxiquin is generally well tolerated. A few side effects may appear during the first several days, including nausea, vomiting, an upset stomach, loss of appetite, diarrhea, tiredness, weakness, headache, or visual disturbances.
Can I take Hydroxychloroquine Sulfate 300 during pregnancy or while breastfeeding?
During pregnancy, use this drug only if clearly needed. Since small amounts pass into breast milk, consult your doctor before use. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Hydroxychloroquine Sulfate 300?
An overdose of hydroxychloroquine sulphate can cause headache, drowsiness, visual disturbances, cardiovascular collapse and convulsions. These can be followed by sudden and early respiratory and cardiac arrest. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Hydroxychloroquine Sulfate 300?
Store Hydroxychloroquine Sulphate below 30°C, away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Hydroxychloroquine Sulfate 300?
Some medicines can interact with Hydroxychloroquine Sulphate, for example: Cyclosporine, Mefloquine, Digoxin, Methotrexate, Insulin (Human) 30/70, Aluminium Hydroxide + Magnesium Hydroxide. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Hydroxychloroquine Sulfate 300?
Hydroxychloroquine Sulfate 300 is a prescription (Rx) medicine. Take it as your doctor advises.