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Indications & Uses
Histason is indicated for:
Pharmacology
Chlorpheniramine Maleate belongs to the alkylamine group of antihistamines and is regarded as one of the most potent H1-receptor blockers available. It works by competitively blocking H1 receptors, and compared with promethazine, it generally produces less sedation.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults: the usual dose is 4 mg every 4 to 6 hours, up to a maximum of 24 mg a day. Children aged 6 to 12 years: 2 mg every 4 to 6 hours, up to a maximum of 12 mg a day. Children aged 2 to 5 years: 1 mg every 4 to 6 hours, up to a maximum of 6 mg a day. Children aged 1 to 2 years: 1 mg twice a day. Chlorpheniramine Maleate is not recommended for children under 1 year of age.
Side Effects
Antismin is generally well tolerated. Occasionally, it may cause drowsiness, dizziness, muscle weakness, or stomach upset.
Cautions & Contraindications
Warnings & Precautions
Antismin should be used with caution in patients with glaucoma or an enlarged prostate (prostatic hypertrophy). While taking chlorpheniramine, care should be taken when driving or operating machinery.
Contraindications
Chlorpheniramine should not be used in people who are allergic to it, or in newborn or premature babies.
Pregnancy & Breastfeeding
Chlorpheniramine maleate should be avoided by breastfeeding mothers and by pregnant women, particularly during the first trimester.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
An overdose of Chlorpheniramine Maleate can cause CNS depression, which includes sedation, apnea and CV collapse. It can also cause CNS stimulation, which includes insomnia, hallucination, tremors and convulsions. Other signs are tinnitus, blurred vision, dizziness, ataxia and hypotension.
Stimulation and atropine-like signs and symptoms are more likely in children. These include dry mouth, fixed dilated pupils, flushing, hyperthermia and Gl symptoms.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Chlorpheniramine Maleate in a cool, dry place, below 25°C, and away from light. Keep it out of the reach of children.
Drug Interactions
Common questions about Histason 2 mg/5 ml
What is Histason 2 mg/5 ml Syrup?
Histason 2 mg/5 ml Syrup is a medicine that contains Chlorpheniramine Maleate. It is made by Hudson Pharmaceuticals Ltd. It belongs to the Sedating Anti-histamine group of medicines.
What is Histason used for?
Histason is used for: Allergic Rhinitis, Cough, Nausea and Vomiting, Urticaria, Edema.
What are the side effects of Histason?
Antismin is generally well tolerated. Occasionally, it may cause drowsiness, dizziness, muscle weakness, or stomach upset.
Can I take Histason during pregnancy or while breastfeeding?
Chlorpheniramine maleate should be avoided by breastfeeding mothers and by pregnant women, particularly during the first trimester. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Histason?
An overdose of Chlorpheniramine Maleate can cause CNS depression, which includes sedation, apnea and CV collapse. It can also cause CNS stimulation, which includes insomnia, hallucination, tremors and convulsions. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Histason?
Keep Chlorpheniramine Maleate in a cool, dry place, below 25°C, and away from light. Keep it out of the reach of children.
Can I take other medicines with Histason?
Some medicines can interact with Chlorpheniramine Maleate, for example: Noradrenaline, Kanamycin, Adrenaline. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Histason?
Histason is a prescription (Rx) medicine. Take it as your doctor advises.