Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago
Available as: 10 mg/ml

More from Histacin

Other strengths and forms by Jayson Pharmaceuticals Ltd.

Indications & Uses

Pharmacology

Chlorpheniramine Maleate belongs to the alkylamine group of antihistamines and is regarded as one of the most potent H1-receptor blockers available. It works by competitively blocking H1 receptors, and compared with promethazine, it generally produces less sedation.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Adults: the usual dose is 4 mg every 4 to 6 hours, up to a maximum of 24 mg a day. Children aged 6 to 12 years: 2 mg every 4 to 6 hours, up to a maximum of 12 mg a day. Children aged 2 to 5 years: 1 mg every 4 to 6 hours, up to a maximum of 6 mg a day. Children aged 1 to 2 years: 1 mg twice a day. Chlorpheniramine Maleate is not recommended for children under 1 year of age.

Side Effects

Antismin is generally well tolerated. Occasionally, it may cause drowsiness, dizziness, muscle weakness, or stomach upset.

Cautions & Contraindications

Warnings & Precautions

Antismin should be used with caution in patients with glaucoma or an enlarged prostate (prostatic hypertrophy). While taking chlorpheniramine, care should be taken when driving or operating machinery.

Contraindications

Chlorpheniramine should not be used in people who are allergic to it, or in newborn or premature babies.

Pregnancy & Breastfeeding

Chlorpheniramine maleate should be avoided by breastfeeding mothers and by pregnant women, particularly during the first trimester.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Overdose

An overdose of Chlorpheniramine Maleate can cause CNS depression, which includes sedation, apnea and CV collapse. It can also cause CNS stimulation, which includes insomnia, hallucination, tremors and convulsions. Other signs are tinnitus, blurred vision, dizziness, ataxia and hypotension.

Stimulation and atropine-like signs and symptoms are more likely in children. These include dry mouth, fixed dilated pupils, flushing, hyperthermia and Gl symptoms.

⚠️ In an emergency call 999 or go to the nearest hospital emergency department.

Storage

Keep Chlorpheniramine Maleate in a cool, dry place, below 25°C, and away from light. Keep it out of the reach of children.

Drug Interactions

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Moderate Noradrenaline
Moderate Kanamycin
Moderate Adrenaline

Common questions about Histacin 10 mg/ml

What is Histacin 10 mg/ml Injection?

Histacin 10 mg/ml Injection is a medicine that contains Chlorpheniramine Maleate. It is made by Jayson Pharmaceuticals Ltd. It belongs to the Sedating Anti-histamine group of medicines.

What is Histacin used for?

Histacin is used for: Allergic Rhinitis, Cough, Nausea and Vomiting, Urticaria, Edema.

What are the side effects of Histacin?

Antismin is generally well tolerated. Occasionally, it may cause drowsiness, dizziness, muscle weakness, or stomach upset.

Can I take Histacin during pregnancy or while breastfeeding?

Chlorpheniramine maleate should be avoided by breastfeeding mothers and by pregnant women, particularly during the first trimester. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

What happens if I take too much Histacin?

An overdose of Chlorpheniramine Maleate can cause CNS depression, which includes sedation, apnea and CV collapse. It can also cause CNS stimulation, which includes insomnia, hallucination, tremors and convulsions. In an emergency call 999 or go to the nearest hospital emergency department.

How should I store Histacin?

Keep Chlorpheniramine Maleate in a cool, dry place, below 25°C, and away from light. Keep it out of the reach of children.

Can I take other medicines with Histacin?

Some medicines can interact with Chlorpheniramine Maleate, for example: Noradrenaline, Kanamycin, Adrenaline. Tell your doctor or pharmacist about every medicine you take.

Do I need a prescription for Histacin?

Histacin is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 15 Aug 2026