Informational only — Not medical advice. Always consult a licensed healthcare provider.

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More from Gynastin

Other strengths and forms by The ACME Laboratories Ltd.

Indications & Uses

Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin is used for vaginal trichomoniasis and vaginal leucorrhoea. It is also used for mixed vaginal infections, whether fungal or bacterial.

Pharmacology

Metronidazole is a nitroimidazole and works against many anaerobic bacteria and protozoa. Nystatin is a polyene antibiotic that acts against fungi. Neomycin is an aminoglycoside, and it kills bacteria (it is bactericidal), including some gram-positive and gram-negative organisms. Polymyxin B is active against gram-negative organisms, Pseudomonas aeruginosa among them.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Insert one suppository into the vagina at bedtime for 12 days, or follow the physician's directions if they differ.

Side Effects

Skin rash and urticaria may occur, but rarely.

Cautions & Contraindications

Warnings & Precautions

Take care if you have renal impairment.

Contraindications

Don't use this medicine if you are hypersensitive to Metronidazole, Neomycin Sulphate, Polymyxin B Sulphate or Nystatin.

Pregnancy & Breastfeeding

Take care when using this medicine in pregnancy and while breastfeeding.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Storage

Keep this medicine in a cool, dry place, away from light and out of children's reach.

Common questions about Gynastin

What is Gynastin Vaginal Suppository?

Gynastin Vaginal Suppository is a medicine that contains Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin. It is made by The ACME Laboratories Ltd. It belongs to the Drugs used in Vaginal and Vulval condition group of medicines.

What is Gynastin used for?

Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin is used for vaginal trichomoniasis and vaginal leucorrhoea. It is also used for mixed vaginal infections, whether fungal or bacterial.

What are the side effects of Gynastin?

Skin rash and urticaria may occur, but rarely.

Can I take Gynastin during pregnancy or while breastfeeding?

Take care when using this medicine in pregnancy and while breastfeeding. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

How should I store Gynastin?

Keep this medicine in a cool, dry place, away from light and out of children's reach.

Do I need a prescription for Gynastin?

Gynastin is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 18 Aug 2026