GoodGut

Studies of probiotic activity in recent years show that probiotics work against gastrointestinal inflammation, both experimental and in humans (human inflammatory bowel disease). They do this through their effects on epithelial cell function, including the barrier function of the epithelial cells, cytokine secretion by the epithelium and antibacterial effects linked to colonization of the epithelial layer. Probiotic Combination lowers gastrointestinal pH by stimulating the lactic-acid-producing bacteria, and it acts directly against gastrointestinal pathogens. It also competes with pathogens for binding and receptor sites. There is emerging evidence, too, that probiotics induce regulatory T cells, which act as a brake on the effector T cells that would otherwise cause inflammation. Lactobacillus acidophilus and Bifidobacterium bifidum appear to increase the nonspecific immune phagocytic activity of circulating blood granulocytes. This effect may account, in part, for the stimulation of IgA responses in infants infected with rotavirus. Lactic acid bacteria, such as strains of Lactobacillus acidophilus and Lactobacillus bulgaricus, have also shown antioxidant ability. The mechanisms include chelation of metal ions (iron, copper), scavenging of reactive oxygen species and reducing activity.

Probiotics are unlikely to reach the fetus through the blood, so they are unlikely to cause harm in pregnancy. They are also unlikely to pass into breast milk.

Keep Probiotic Combination below 25ºC, in a dry place and away from direct sunlight. Keep it out of reach of children.