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Indications & Uses
Betaxolol Hydrochloride ophthalmic solution lowers intraocular pressure, and it has been shown to work. Doctors prescribe it for ocular hypertension and for chronic open-angle glaucoma. You can use Betaxolol Hydrochloride on its own, or together with other medicine that lowers intraocular pressure.
Pharmacology
Betaxolol is a selective beta-1-adrenergic receptor blocking agent. It has no significant membrane stabilizing (local anesthetic) activity and no intrinsic sympathomimetic action. When it is instilled into the eye, Betaxolol lowers raised intraocular pressure and also normal intraocular pressure, whether or not the person has glaucoma. A sustained rise in intraocular pressure and poor ocular perfusion lead to optic nerve head damage and visual field loss.
The pressure-lowering effect of Betaxolol appears to come from a reduction in aqueous production, as shown by tonography and aqueous flurophotometry. Unlike miotics, Betaxolol ophthalmic solution does not cause miosis or accommodative spasm, which are frequently seen with those medicines.
The effect can generally be noticed within 30 minutes of topical use, and the maximal effect can usually be detected two hours after administration. A single dose reduces intraocular pressure (IOP) for 12 hours, and with twice daily use the IOP stays below 22 mm Hg in most patients.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
0.5% ophthalmic solution: The usual dose of Betaxolol Hydrochloride is 1 drop in the affected eye(s) twice daily. In some patients the fall in intraocular pressure can take a few weeks to settle. The pressure should be checked during the first month of treatment. After that, the doctor decides on an individual basis when it needs to be checked again.
0.25% ophthalmic solution: The recommended dose of Betaxolol Hydrochloride is one to two drops in the affected eye(s) twice daily.
Pediatric Use: Safety and effectiveness in pediatric patients have not been established.
Geriatric Use: No overall differences in safety or effectiveness have been seen between elderly and younger patients.
Side Effects
Ocular: Betaxolol Hydrochloride can cause short-lived discomfort in the eye, and occasional tearing has been reported. Decreased corneal sensitivity, erythema, an itching sensation, corneal punctuate staining, keratitis, edema and photophobia have also been reported, but these are rare. Systemic: Systemic reactions after using Betaxolol Hydrochloride ophthalmic solution 0.5% have been reported only rarely. They include the following. Cardiovascular: bradycardia, heart block, congestive heart failure. Respiratory: bronchospasm, respiratory failure. Others: hives, toxic epidermal necrolysis, hair loss and glossitis.
Cautions & Contraindications
Warnings & Precautions
In angle-closure glaucoma, the first aim of treatment is to re-open the angle by narrowing the pupil with a miotic. Betaxolol Hydrochloride has no effect on the pupil, so in angle-closure glaucoma it should be used together with a miotic to bring down the raised intraocular pressure. Beta-adrenergic blocking agents need to be given with caution to patients who are prone to spontaneous hypoglycemia, and to diabetic patients, because these agents may mask the signs and symptoms of acute hypoglycemia.
Contraindications
Don't use betaxolol if you are allergic to it or to any other component of the product. It should also not be used in people with sinus bradycardia, in those with atrioventricular block greater than first degree, or in those with cardiogenic shock. People with a history of overt cardiac failure should not use it either.
Pregnancy & Breastfeeding
No adequate and well controlled studies have been done in pregnant women. Betaxolol ophthalmic solution should be used during pregnancy only if the possible benefit justifies the possible risk.
It is not known whether betaxolol passes into human milk. The risk of hypoglycemia and bradycardia in a nursing infant has not been evaluated. Breastfeeding is not recommended during treatment.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
There is no information available on overdosage. If too much Betaxol ophthalmic solution gets into the eye(s), you can flush it out with warm tap water.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Betaxolol Hydrochloride at room temperature. Once you've opened the bottle, it's best not to use what's left after one month.
Common questions about Glucovis 0.25%
What is Glucovis 0.25% Ophthalmic Solution?
Glucovis 0.25% Ophthalmic Solution is a medicine that contains Betaxolol Hydrochloride. It is made by Beximco Pharmaceuticals Ltd. It belongs to the Drugs for miotics and glaucoma group of medicines.
What is Glucovis used for?
Betaxolol Hydrochloride ophthalmic solution lowers intraocular pressure, and it has been shown to work. Doctors prescribe it for ocular hypertension and for chronic open-angle glaucoma.
What are the side effects of Glucovis?
Ocular: Betaxolol Hydrochloride can cause short-lived discomfort in the eye, and occasional tearing has been reported. Decreased corneal sensitivity, erythema, an itching sensation, corneal punctuate staining, keratitis, edema and photophobia have also been reported, but these are rare.
Can I take Glucovis during pregnancy or while breastfeeding?
No adequate and well controlled studies have been done in pregnant women. Betaxolol ophthalmic solution should be used during pregnancy only if the possible benefit justifies the possible risk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Glucovis?
There is no information available on overdosage. If too much Betaxol ophthalmic solution gets into the eye(s), you can flush it out with warm tap water. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Glucovis?
Keep Betaxolol Hydrochloride at room temperature. Once you've opened the bottle, it's best not to use what's left after one month.
Do I need a prescription for Glucovis?
Glucovis is a prescription (Rx) medicine. Take it as your doctor advises.