Indications & Uses
Topical antiseptic used as first aid to help prevent infection in minor cuts, scrapes, and burns.
Pharmacology
In aqueous solutions, gentian violet (GV) dissociates into positive (GV+) and negative (Cl−) ions that penetrate through the wall and membrane of both gram-positive and gram-negative bacterial cells. The GV+ ion interacts with negatively charged components of bacterial cells, including the lipopolysaccharide on the cell wall, the peptidoglycan, and DNA. A similar process of cell penetration and DNA binding is thought to occur in fungal cells as well. Because gentian violet is a mutagen and mitotic poison, it consequently inhibits cell growth. A photodynamic action of gentian violet, apparently mediated by a free-radical mechanism, has also been described in bacteria and in the protozoan T. cruzi. Evidence further suggests that gentian violet dissipates the bacterial (and mitochondrial) membrane potential by inducing permeability, which is then followed by respiratory inhibition. This anti-mitochondrial activity may explain why gentian violet is effective against both bacteria and yeast while having relatively mild effects on mammalian cells.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Clean the affected area, then apply a small amount of this product 1 to 3 times a day. The area may be covered with a sterile bandage afterward.
Side Effects
Redness, irritation, swelling, or pain that persists, worsens, or is accompanied by signs of infection.
Cautions & Contraindications
Warnings & Precautions
Stop using it if the condition does not get better or gets worse. Do not use it for longer than 1 week.
Contraindications
Do not apply to open sores or ulcerated skin, as it may permanently stain (tattoo) the affected area.
Pregnancy & Breastfeeding
Pregnancy Category: Not classified. The FDA has not yet placed this drug into a specific pregnancy category.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Common questions about Gentian Violet 100 %
What is Gentian Violet 100 % Powder?
Gentian Violet 100 % Powder is a medicine that contains Gentian Violet. It is made by EDCL (Dhaka). It belongs to the Crystal violet/ Gentian violet preparations group of medicines.
What is Gentian Violet used for?
Topical antiseptic used as first aid to help prevent infection in minor cuts, scrapes, and burns.
What are the side effects of Gentian Violet?
Redness, irritation, swelling, or pain that persists, worsens, or is accompanied by signs of infection.
Can I take Gentian Violet during pregnancy or while breastfeeding?
Pregnancy Category: Not classified. The FDA has not yet placed this drug into a specific pregnancy category. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Do I need a prescription for Gentian Violet?
Gentian Violet is a prescription (Rx) medicine. Take it as your doctor advises.