Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Fosamin is indicated for:
Pharmacology
Fosfomycin Trometamol is a phosphonic acid derivative. It's a synthetic, broad spectrum, bactericidal antibiotic that you take by mouth. In the laboratory (in vitro), fosfomycin is active against a broad range of gram-positive and gram-negative aerobic microorganisms that are associated with uncomplicated urinary tract infections.
The bactericidal action of Fosfomycin comes from inactivating the enzyme enolpyruvyl transferase. This irreversibly blocks the condensation of uridine diphosphate N-acetylglucosamine with p-enolpyruvate, which is one of the first steps in bacterial cell wall synthesis.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For women aged 18 years and older with acute cystitis, the recommended dose of Fosfomycin is one sachet, taken with or without food. Don't give this medicine to children.
Preparation: first pour 100 ml of purified water into a glass. Then add the full contents of one Fosfomycin sachet to the water and stir until it dissolves completely. Drink the whole mixture straight away after preparing it.
Side Effects
In clinical trials of Fosfomycin Trometamol, the side effects reported most often, in more than 1% of the people studied and whether or not the medicine was the cause, were diarrhea 10.4%, headache 10.3%, vaginitis 7.6%, nausea 5.2%, rhinitis 4.5%, back pain 3.0%, dysmenorrhea 2.6%, pharyngitis 2.5%, dizziness 2.3%, abdominal pain 2.2%, pain 2.2%, dyspepsia 1.8%, asthenia 1.7% and rash 1.4%. Other events turned up in less than 1% of people in the trials, again regardless of whether the medicine was responsible. These were abnormal stools, anorexia, constipation, dry mouth, dysuria, ear disorder, fever, flatulence, flu syndrome, hematuria, infection, insomnia, lymphadenopathy, menstrual disorder, migraine, myalgia, nervousness, paresthesia, pruritus, SGPT increased, skin disorder, somnolence and vomiting.
Cautions & Contraindications
Warnings & Precautions
Clostridium difficile associated diarrhea (CDAD) has been reported with nearly all antibacterial agents, and Fosfomycin Trometamol is one of them. These medicines change the normal flora of the colon, and that can let C. difficile overgrow. Don't give more than one single dose of Fosfomycin Trometamol for a single episode of acute cystitis. In studies, repeated daily doses didn't improve the clinical success or microbiological eradication rates compared with single dose therapy, but they did increase the incidence of adverse events.
Contraindications
Fosfomycin trometamol should not be given to anyone who is known to be hypersensitive to the drug. It is also contraindicated in patients with severe renal insufficiency and in those undergoing haemodialysis.
Pregnancy & Breastfeeding
Fosfomycin trometamol is pregnancy category B. Doctors should not give it during pregnancy unless the benefit outweighs the risk. For breastfeeding, a decision has to be made either to stop breastfeeding or not to give the medicine, and this should take into account how important the medicine is for the mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Metoclopramide increases gastrointestinal motility, and when it is taken together with Fosfomycin Trometamol, it lowers the serum concentration of fosfomycin and also reduces how much is passed out in the urine. Other medicines that increase gastrointestinal motility may have a similar effect.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Fosfomycin Trometamol out of reach of children. Store it in a dry place, below 25°C and protected from light.
Drug Interactions
Common questions about Fosamin 3 gm
What is Fosamin 3 gm Oral Powder?
Fosamin 3 gm Oral Powder is a medicine that contains Fosfomycin Trometamol. It is made by Beximco Pharmaceuticals Ltd. It belongs to the Intracellular antibiotic group of medicines.
What is Fosamin used for?
Fosamin is used for: Urinary Tract Infection.
What are the side effects of Fosamin?
In clinical trials of Fosfomycin Trometamol, the side effects reported most often, in more than 1% of the people studied and whether or not the medicine was the cause, were diarrhea 10.4%, headache 10.3%, vaginitis 7.6%, nausea 5.2%, rhinitis 4.5%, back pain 3.0%, dysmenorrhea 2.6%, pharyngitis 2.5%, dizziness 2.3%, abdominal pain 2.2%, pain 2.2%, dyspepsia 1.8%, asthenia 1.7% and rash 1.4%. Other events turned up in less than 1% of people in the trials, again regardless of whether the medicine was responsible.
Can I take Fosamin during pregnancy or while breastfeeding?
Fosfomycin trometamol is pregnancy category B. Doctors should not give it during pregnancy unless the benefit outweighs the risk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Fosamin?
Metoclopramide increases gastrointestinal motility, and when it is taken together with Fosfomycin Trometamol, it lowers the serum concentration of fosfomycin and also reduces how much is passed out in the urine. Other medicines that increase gastrointestinal motility may have a similar effect. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Fosamin?
Keep Fosfomycin Trometamol out of reach of children. Store it in a dry place, below 25°C and protected from light.
Can I take other medicines with Fosamin?
Some medicines can interact with Fosfomycin Trometamol, for example: Metoclopramide. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Fosamin?
Fosamin is a prescription (Rx) medicine. Take it as your doctor advises.